Oral Manifestations of Chronic Renal Failure Complicating a Systemic Genetic Disease: Diagnostic Dilemma. Case Report and Literature Review

Benmoussa, L.; Renoux, M; Radoï, Loredana

doi:10.1016/j.joms.2015.05.029

Cited by 12 publications

(17 citation statements)

References 32 publications

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“…also found a high percentage of pulp calcifications [17]. Alterations in trabecular pattern were found in 51.81% of our patients and this result is comparable with the cases published by De Lacerda and Benmoussa [18,19]. 9 patients from our study presented brown tumors.…”

Section: Table 1 the Etiology Of Renal Diseasesupporting

confidence: 91%

Oral and Maxillofacial Manifestations of Mineral and Bone Disorders Associated with Chronic Renal Failure

Doscas¹,

Bălan²,

Ciofu³

et al. 2017

Rev. Chim.

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Chronic kidney disease (CKD) is a multifactorial syndrome and a global health concern. As renal function declines, there is a progressive deterioration of mineral homeostasis. Starting from stage 3 of CKD oral manifestations of mineral disorders can occasionally appear and become more frequent and evident in stage 5. We retrospectively analysed 43 patients diagnosed with end stage renal failure undergoing dialysis, hospitalized in our clinic for different oral and maxillofacial pathologies. The mean dialysis period was 5.43 years. Radiographic alterations afecting the jaws were found in all patients. The most common feature was partial or total loss of lamina dura, followed by alterations of the bony trabeculae. 9 patients presented brown tumors which are considered the final stage of secondary hyperparathyroidism associated with renal failure.

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Section: Table 1 the Etiology Of Renal Diseasesupporting

confidence: 91%

Oral and Maxillofacial Manifestations of Mineral and Bone Disorders Associated with Chronic Renal Failure

Doscas¹,

Bălan²,

Ciofu³

et al. 2017

Rev. Chim.

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“…8,10,[25][26][27][28][29][30][31] Oral manifestations of hyperoxaluria are rare. Among the main complications: hypodontia and microdontia, dental pain, 26,30 root resorption, 31 periodontal diseases 8,10 and bone alterations such as radiolucencies in the F I G U R E 4 A conformation of the hands-particular jaws 32 are described. 22 These alterations are due to both the primary disease and to secondary parathyroidism due to the chronic renal failure, as well as to the transplantation sequelae and protracted pharmacological treatments.…”

Section: Discussionmentioning

confidence: 99%

Primary hyperoxaluria: Orthodontic management in a pediatric patient: A case report

Cazzolla

Zhurakivska

Ciavarella

et al. 2018

Special Care in Dentistry

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“…Subperiosteal bone resorption of the middle phalanges of the fingers has been recognized as the first radiographic finding of bone loss resulting from hyperparathyroidism and the marked increase in PTH levels [5,8,9,[18][19][20][21]. The PCI uses hand and wrist radiographs to evaluate the cortical morphology of the middle phalanges of patients with chronic kidney disease and secondary hyperparathyroidism, and consists of three levels of severity (P1, P2, P3) which correlate directly with increases in hormone levels [7].…”

Section: Discussionmentioning

confidence: 99%

“…The middle phalanges of the middle and index fingers are the first bone sites to undergo the osteoporotic processes resulting from SHPT [9,[13][14][15][16][17][18][19][20]. Recently, a marked correlation was demonstrated between PTH levels and the state of resorption of the middle phalanges of the middle and index fingers of the right and left hands, by means of applying the Phalangeal Cortical Index (PCI) to hand and wrist radiographs [7,8].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of renal osteodystrophy in the dental clinic by assessment of mandibular and phalangeal cortical indices

et al. 2017

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Objectives Secondary hyperparathyroidism (SHPT) is a disease that affects patients with chronic kidney disease, and is characterized by mineral disturbance and bone loss, known as renal osteodystrophy. The aim of this study was to assess the validity of using intraoral phosphor storage plates to take radiographs of the middle phalanges to evaluate bone loss resulting from SHPT during follow-up of these patients. Methods The sample consisted of 24 patients with chronic kidney disease, 12 with parathyroid hormone (PTH) levels C500 pg/ml, and 12 with PTH levels \500 pg/ml, who underwent hemodialysis weekly. For each patient, a panoramic radiograph and digital radiographs of the ring, index, and middle fingers of both hands were taken. The Mandibular Cortical Index (MCI) and the Trabecular Bone Pattern Index (TBP) were applied to the panoramic radiographs, while the Phalangeal Cortical Index (PCI) was applied to the digital radiographs of the phalanges. Three evaluators performed all analyses. Results Significant correlations were found between the PTH levels and the MCI (p = 0.023), the PCI (p = 0.039) and the TBP index (p = 0.032). These parameters were also significantly interrelated (MCI 9 PCI = 0.001; MCI 9 TBP = 0.004 and PCI 9 TBP = 0.009). The PCI was shown to have the highest correlation with PTH levels. Conclusion In patients with chronic renal disease, it is clinically relevant to use panoramic and digital radiographs using intraoral storage plates to assess a number of quantitative parameters that can be linked to PTH levels.

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Oral Manifestations of Chronic Renal Failure Complicating a Systemic Genetic Disease: Diagnostic Dilemma. Case Report and Literature Review

Cited by 12 publications

References 32 publications

Oral and Maxillofacial Manifestations of Mineral and Bone Disorders Associated with Chronic Renal Failure

Oral and Maxillofacial Manifestations of Mineral and Bone Disorders Associated with Chronic Renal Failure

Primary hyperoxaluria: Orthodontic management in a pediatric patient: A case report

Evaluation of renal osteodystrophy in the dental clinic by assessment of mandibular and phalangeal cortical indices

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