Oral Manifestations of Celiac Disease

Pastore, Luca; Carroccio, Antonio; Compilato, Domenico; Panzarella, Vera; Serpico, Rosario; Muzio, Lorenzo Lo

doi:10.1097/mcg.0b013e318074dd98

Cited by 105 publications

(121 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Costacurta et al observed a more frequent occurrence of caries in patients with this disease [16]. Nevertheless, in the literature an opposite view is more frequent [8,14,17,35,36]. It may be the effect of better control over a diet, and a smaller number of snacks [36], as well as better oral cavity hygiene [13].…”

mentioning

confidence: 99%

Celiac Disease and Its Impact on the Oral Health Status – Review of the Literature

B¹,

Herman²,

Kowalczyk−Zając³

et al. 2014

Adv Clin Exp Med

View full text Add to dashboard Cite

The paper presents the most recent reports on celiac disease, especially its manifestations within the oral cavity. Particular attention should be paid to typical dental enamel defects with a various degree of advancement: discolorations, horizontal groves and pits, and even significant structural destruction causing the change of the dental crown. Symmetric location of defects within all dentition sections, and within the same anatomic groups of teeth (the most frequently: incisors and first permanent molars), is specific for celiac disease. The changes described above may be the only manifestation of celiac disease; therefore, in the case of their occurrence further studies towards gluten intolerance are recommended even when other symptoms are not present. In celiac patients, recurrent aphthae and other disorders of the oral mucosa such as ulceration, erythema, atrophic glossitis, as well as dryness and a burning sensation (particularly of the tongue) may be present, which may be caused by malnutrition. Delayed tooth eruption may also be a consequence of alimentary deficiency in celiac disease (Adv Clin Exp Med 2014, 23, 5, 675-681).

show abstract

mentioning

confidence: 99%

Celiac Disease and Its Impact on the Oral Health Status – Review of the Literature

B¹,

Herman²,

Kowalczyk−Zając³

et al. 2014

Adv Clin Exp Med

View full text Add to dashboard Cite

show abstract

“…The overall prevalence of systemic dental enamel defects in CD patients with mixed or permanent dentition ranges from 9.5% to 95.9% (mean 51.1%); the prevalence in the deciduous dentition is 5.8% to 13.3% (mean 9.6%) 9 . An Italian study which assessed 166 patients between 2 and 17 years of age, reported the prevalence of RAU as 69% in CD patients versus 43% in the control group which was statistically significant.…”

Section: Epidemiologymentioning

confidence: 99%

Coeliac disease in children – an update for general dental practitioners

et al. 2016

View full text Add to dashboard Cite

Coeliac disease (CD) is an immune-mediated systemic disorder caused by ingestion of gluten found in wheat, rye and barley. It affects around 1% of children but 90% of cases are considered to remain undiagnosed. CD classically presents with gastrointestinal manifestations including diarrhoea, bloating, weight loss and abdominal pain, but extra-intestinal features (including oral and dental manifestations) are increasingly being reported. Dental and oral manifestations such as dental enamel defects, delayed eruption of teeth, recurrent aphthous ulcers are well recognized manifestations of CD. In patients with yet undiagnosed CD, these can sometimes be the only presenting features. Dentists have regular contact with well children, and therefore the visit to the dentist is an opportunity to suspect CD. When CD is suspected, Dental practitioners can liaise with the General Medical Practitioner to organise screening for coeliac disease. Positive serology will prompt onward referral to a paediatric gastroenterologist to confirm the diagnosis. The recent European Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) guidelines have streamlined the diagnostic pathway for faster diagnosis of CD. Management involves strict adherence to a gluten free diet, which should lead to resolution of symptoms, recovery of intestinal mucosa and prevention of long-term complications associated with it. This article aims to describe CD, inform of recent changes to the diagnostic pathway and highlight the dental manifestations of the condition to equip Dental practitioners to aid early diagnosis and initiation of treatment for children with CD.

show abstract

“…Nutritional disturbances due to malabsorption are also considered to play a role [47]. The overall prevalence of dental enamel defects in celiac disease patients with a primary dentition is 5.8% to 13.3%, while that in celiac disease patients with a permanent dentition ranges from 9.5% to 95.9% [44]. This difference between dentitions can be attributed to the fact that the permanent teeth develop during the early months of life, after the introduction of gluten in the diet, while primary teeth develop before birth.…”

Section: Enamel Defectsmentioning

confidence: 99%

“…The precise mechanism underlying the development of enamel defects in celiac disease patients remains unclear, although several hypotheses have been suggested. The most wellaccepted mechanism is immune-mediated damage [44], followed by stimulation of lymphocytes in the oral cavity by gluten [45]. Munoz et al reported that anti-gliadin antibodies, which are present in celiac disease patients, may react with enamel matrix proteins (amelogenin and ameloblastin) [46].…”

Section: Enamel Defectsmentioning

confidence: 99%

“…Federico et al [59] studied the effects of a gluten-free diet on growth factors in patients with celiac disease and found that multiple alterations in the growth axis observed during the active phase of the disease disappeared during the gluten-free diet [59]. With regard to caries, the frequency is lower in celiac disease patients than in healthy individuals, probably because of better diet control in the former [31,44,54,60]. In contrast to these findings, some studies have reported a higher frequency of caries in the permanent dentition of celiac disease patients [30,38,39].…”

Section: Other Oral Manifestationsmentioning

confidence: 99%

See 1 more Smart Citation