The Effect of Celiac Disease on the Oral Cavity: A Review )

Al-Homaidhi, Majedah A.

doi:10.15406/jdhodt.2018.09.00327

Cited by 1 publication

(1 citation statement)

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“…The cause of RAS is not clear [1,3]. It is seen in otherwise healthy people, but also in various infectious and non-infectious diseases, including celiac disease (CD) [1,[6][7][8][9][10][11][12][13][14][15]. In addition, RAS is associated with genetic predisposition, iron and vitamin B12 deficiency, local mechanical injuries, stress, and hormonal imbalance [16,17,18].…”

Section: Introductionmentioning

confidence: 99%

Recurrent aphthous stomatitis as the only clinical sign of celiac disease in obese adolescent - case report and literature review

et al. 2020

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Introduction. Recurrent aphthous stomatitis (RAS) is a relatively common oral mucosal lesion of unclear etiology. It occurs in otherwise healthy people, but also in various infectious and non-infectious diseases, including celiac disease (CD). We present an obese adolescent with RAS as the only clinical sign of CD. Case outline. Adolescent aged 15 2/12 years come with very pronounced RAS in the last 5 months. He had no other difficulties. Obese from the age of 12. Other data without peculiarities. On admission, 165 cm tall (P25), obese (BMI 27 kg/m2), in the final stage of puberty, with stretch marks in the distal areas of the abdomen, thighs and gluteus and very pronounced pain-sensitive aphthae in the buccal and labial mucosa accompanied by swelling of the lips and perioral region. Except for lower serum iron levels (8 ?mol/l), routine laboratory blood tests were within the reference range. The serological test for CD was positive (antibodies to tissue transglutaminase IgA 78.5 U/ml, anti-endomysial antibodies IgA positive). Endoiscopy revealed reflux esophagitis, without any other pathological findings. Stereomicroscopic and pathohistological analysis of the duodenal mucosa samples showed mild destructive enteropathy (Marsh IIIa). Pathohistological examination of the gastric mucosa revealed grade I-II lymphocytic gastritis. The urease test for Helicobacter pylori was negative. A gluten-free diet resulted in the withdrawal of aphthous stomatitis and no recurrence later. Conclusion. Within the differential-diagnostic analysis of the RAS causes CB should be considered as well. Additionally, obesity does not exclude the presence of the CB.

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