Malaria is a parasitic infectious disease of Plasmodium genus, which has become a momentous public health issue. According to the data of World Health Organization (WHO), in 2017, about 87 countries and areas suffered from such a global infectious disease (indigenous malaria), and nearly fifty percent of the global population was at risk for malaria infection; 219 million cases of malaria were reported, causing 435,000 fatalities (children aged under 5 years accounted for 61% [266 000]) all over the world. Although the incidence of malaria globally declined in recent decades, the rate of change seemed to be stalled during -2017 (World Malaria Report, 2018.The Plasmodium infection, especially Plasmodium falciparum, exhibits diversiform clinical manifestations; therefore, it cannot be easily diagnosed and mostly relies on laboratory examinations (Mace, Arguin, Lucchi, & Tan, 2019). Identification of typical symptoms may facilitate accurate diagnosis of malaria, including fever, headache, chills/shivering, sweating, fatigue/weakness, myalgia, and arthralgia (Mace et al., 2019). Cerebral malaria or other organ dysfunction is commonly regarded as an indicator of the severity of malaria, which often occurs in cases of Plasmodium falciparum infection (Elnour, Alagib, Bansal, Farag, & Malik, 2019).Although typical symptoms have been well recognized, some cases with atypical or rare signs of malaria may be neglected by health professionals, which may delay the diagnosis and