Oral malignant melanoma diagnosed in an Iranian population over an 11-year period

Jahanbani, Jahanfar; Forouzandeh, Aghdas; Sadri, Donya; Mirlashari, Jila

doi:10.1007/s10006-008-0127-3

Cited by 4 publications

(6 citation statements)

References 14 publications

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“…Oral melanomas are more commonly found in the maxilla, especially in the palate and gums [1, 4-6, 14-16]. The mandible is only involved in 20% of cases [5, 17].…”

Section: Review and Discussionmentioning

confidence: 99%

“…Unlike cutaneous melanoma, the pathogenesis and etiogenesis of mucosal melanoma are not yet clear or defined [1, 8, 15, 17, 19]. Sun exposure is not related to the etiology of oral melanoma, but is clearly linked to cutaneous melanoma.…”

Section: Review and Discussionmentioning

confidence: 99%

“…Racial, cultural and geographic factors may also predispose individuals to the disease [20]. Japanese, African, American and Hispanic individuals are more commonly affected by oral melanoma, with a greater predilection for the male gender [1, 5, 21, 22]. However, Pour et al [6] (2009) reported a greater prevalence of oral melanoma among women.…”

Section: Review and Discussionmentioning

confidence: 99%

“…Melanoma originates from the malignant transformation of melanocytes [1]. Oral melanoma is not as common as cutaneous melanoma and has the worst prognosis among malignant tumors [2, 3].…”

Section: Introductionmentioning

confidence: 99%

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Oral and Cutaneous Melanoma: Similarities and Differences

et al. 2010

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“…Oral melanomas are more commonly found in the maxilla, especially in the palate and gums [1, 4-6, 14-16]. The mandible is only involved in 20% of cases [5, 17].…”

Section: Review and Discussionmentioning

confidence: 99%

Section: Review and Discussionmentioning

confidence: 99%

Section: Review and Discussionmentioning

confidence: 99%

“…Melanoma originates from the malignant transformation of melanocytes [1]. Oral melanoma is not as common as cutaneous melanoma and has the worst prognosis among malignant tumors [2, 3].…”

Section: Introductionmentioning

confidence: 99%

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Oral and Cutaneous Melanoma: Similarities and Differences

et al. 2010

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“…It is estimated to represent 1-2% of all oral malignancies and accounts for about 0,1-8% of all melanomas. 6,7,15 Mean age of onset is 55-60, 6,7 however there have been reports of onset in prepubertal children. 16 Unlike cutaneous melanoma, oral melanoma is very frequent in Japan, Uganda and India.…”

Section: Oral Mucosal Melanomamentioning

confidence: 99%

Dermoscopy of pigmented oral lesions

Olszewska

Banka²,

Górska³

et al. 2008

J Dermatol Case Rep

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Dermoscopy is a noninvasive diagnostic technique that permits the visualization of morphologic features that are not visible to the naked eye. It is currently widely used for examination of pigmented skin lesions and early detection of cutaneous melanoma. Dermoscopy of mucous membranes is significantly less investigated and less popular among clinicians.This article reviews current knowledge about characteristic dermoscopy features of pigmented lesions of the oral mucous membranes and lips. It has to emphasized that a major advantage of dermoscopy is the capability to exclude melanoma and avoid unnecessary excisional biopsies and extensive surgery, often resulting in significant disfigurement of face and oral cavity.It has to be pointed out that there is a necessity to intensify research, which would result in clear-cut dermoscopy criteria for mucosal melanoma and the need for constructing thin, flexible dermoscopes suitable for investigation of oral mucous membranes. Dermoscopy is a noninvasive diagnostic technique that permits the visualization of morphologic features that are not visible to the naked eye. It is currently widely used for examination of pigmented skin lesions and early detection of cutaneous melanoma. 1,2 Despite increasing popularity in examination of skin lesion, the methods remains unpopular in investigating pigmented lesions oral mucous membranes and lips. Dermoscopy of pigmented oral lesionsPigmented mucosal lesions represent a group of rare entities differing in etiopathogenesis, histology, dermoscopy and clinical course. Solitary pigmented lesions of melanocytic origin are uncommon in the oral mucosa. These lesions include the oral and labial melanotic macules, oral melanocytic nevi, oral melanoacanthomas and oral melanomas. 3 As shown by Buchner et al 4 oral and labial melanotic macules are the most common melanocytic lesions. The relative frequency of oral melanoma accounts for 0.6% of the entire melanocytic group of oral pigmented lesions (Table 1). Despite low frequency, early detection of melanoma is the main aim of dermoscopic examinations of the oral mucous membranes and the lip. An additional benefit of dermoscopy is exclusion of melanoma of the oral mucous membranes or the lip in doubtful cases, what may save patients the discomfort of extensive and unnecessary surgery.In this paper, we review current knowledge about dermoscopy of pigmented lesions localized on the mucous membranes of the oral cavity and the semi-mucosa of lips. Table 1 Relative frequency of oral solitary melanocytic lesions. 4

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Report of a rare and aggressive case of oral malignant melanoma

Ahmadi‐Motamayel

Falsafi

Baghaei

2012

Oral Maxillofac Surg

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BackgroundOral melanoma is a very rare malignancy with unknown etiology. Its higher incidence is between 41 and 60 years of age. A high localization of oral melanoma was found in the maxilla. Gender distribution was reported as 1:1. Oral melanoma represents 0.2% to 8% of the all the total cases of melanoma of the body.Case reportIn this article we report an aggressive case of oral melanoma in a 71-year-old male with chief complaint of black swelling of the gingiva, paresthesia, and denture ill fitting.DiscussionMost oral melanomas are asymptomatic and painless in early stages and unfortunately diagnosis delayed until symptoms occurred. Early detection of suspected melanotic lesions by patient, dentist, and physician is very important.

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Oral malignant melanoma diagnosed in an Iranian population over an 11-year period

Abstract: The palate was the most common location for oral malignant melanoma. Thus, all melanocytic lesions in the palate should be viewed with caution, and biopsy is recommended to rule out melanoma.

Cited by 4 publications

References 14 publications

Oral and Cutaneous Melanoma: Similarities and Differences

Oral and Cutaneous Melanoma: Similarities and Differences

Dermoscopy of pigmented oral lesions

Report of a rare and aggressive case of oral malignant melanoma

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