Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity

Kõll-Klais, Piret; Mändar, Reet; Leibur, Edvitar; Marcotte, Harold; Hammarström, Lennart; Mikelsaar, Marika

doi:10.1111/j.1399-302x.2005.00239.x

Cited by 248 publications

(229 citation statements)

References 45 publications

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“…Lactobacilli coaggregate with F. nucleatum at nearly 90%, thus modulating composition of oral biofilms. 11 Lactobacilli had been shown to be the strongest inhibitor of AActinimycetemcomitans, P gingivalis and P intermedia, potent microorganisms responsible for periodontal destruction. 20 Probiotic microorganisms do not act exclusively by affecting the microbiota, but also protect the oral cavity through the promotion of a beneficial host response.…”

Section: Discussionmentioning

confidence: 99%

Role of Probiotics on Oral Health - A Randomized, Double Blind, Placebo-Controlled Microbiological Study

Dhawan¹,

Dhawan²

2013

DENT

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The aim of this study was to investigate commercially available combined probiotic formulation for its effect on plaque, gingivitis and salivary Streptococcus mutans levels in subjects with chronic gingivitis. A total of 36 subjects were finally enrolled in a double blind placebo controlled randomized trial. Selected subjects were randomly divided in two groups; Group A (Control group) with 17 subjects, receiving placebo tablets twice daily and Group B (Probiotic group) with 19 subjects receiving probiotic tablets twice daily. The study consisted of two 2 weeks periods, a two week intervention period (T1-T2) and a two week post treatment period (T2-T3). Clinical parameters and bacterial counts of salivary Streptococcus mutans, were evaluated at the baseline (T1), at the completion (T2) of medication and 2 weeks after medication (T3). On comparative evaluation between the two groups, results indicated that Group-B (Probiotic group) exhibited statistically significant reduction in Plaque Index, Gingival index and Streptococcus mutans level than Group-A (Control group) over the entire span of the study. Our results indicated that probiotic could be useful in the improvement/ maintainance of oral health.

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Section: Discussionmentioning

confidence: 99%

Role of Probiotics on Oral Health - A Randomized, Double Blind, Placebo-Controlled Microbiological Study

Dhawan¹,

Dhawan²

2013

DENT

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“…27 Ishikawa et al observed in vitro inhibition of P. gingivalis, P. intermedia, and P. nigrescens by daily ingestion of L. salivarius in tablet form. 28 L. acidophilus contained in a tablet named Acilact was first clinically tested by pozharitskaia et al in 1994 and they found improved clinical parameters in periodontitis patients and shifts in local microflora towards gram positive cocci and lactobacilli. Later in the year 2002 Grudianov et al also carried out a clinical study where they obtained a probiotic mix in the tablet forms, viz Acilact and Bifidumbacterin and found normalization of micro flora and reduction of signs of gingivitis and periodontitis.…”

Section: Probiotics In Periodontal Disease -An Evidence Based Approachmentioning

confidence: 99%

Probiotics and Periodontal Disease - A Review

2015

IJDA

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ABSTRACT:Probiotics are live micro-organisms that when administered in adequate amounts confer health benefits upon the host. A few conventional foods containing probiotics are yogurt, fermented and unfermented milk, soy beverages etc. Most often, they come from two groups of bacteria, Lactobacillus or Bifi dobacterium.Evidence now suggests that probiotics may function not only by direct inhibition of pathogenic micro-organisms, but also by more subtle mechanisms including modulation of the mucosal immune system. Little attention has been paid to the identification of beneficialoral bacterial species. Probiotic technology represents a breakthrough approach to maintaining oral health by using natural beneficial bacteria to provide a natural defense against the pathogenic bacteria species. This review endeavours to introduce the concepts of probiotics in periodontics.

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“…Production of lactic acid (a short chain fatty acid) can penetrate the bacterial membrane and acidify the cytoplasm by inhibiting the proliferation of Porphyromonas gingivalis, Streptococcus mutans [22] and Prevotella intermedia [23]. Lactobacillus gasseri is a homofermentative bacteria (metabolism via glycolysis) that is able to produce large quantities of lactic acid.…”

Section: Local Mechanisms Of Probiotic Actionmentioning

confidence: 99%

Probiotics and Periodontal Diseases

Morales¹,

Bravo²,

Bedoya³

et al. 2017

Insights Into Various Aspects of Oral Health

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Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Probiotics have been used to directly modify the resident oral microbiome and proposed to modulate immune responses. In dentistry, probiotics have been employed as useful adjuncts for the reduction of caries development, suppressing oral Candida infection and controlling halitosis. Plaque-induced gingivitis is a gingival inflammation caused by the adherent bacterial biofilm around teeth. Gingivitis and periodontitis are considered to be a continuum of the same inflammatory process, although many gingivitis lesions do not progress to periodontitis. Periodontitis is an inflammatory process that affects the attachment structures of teeth. It constitutes a second cause of tooth loss worldwide. Conventional treatment modalities of periodontal disease include non-surgical and/or surgical management, with an emphasis on mechanical debridement. However, mechanical debridement as a sole therapy is not always effective to improve clinical parameters. A growing number of studies support probiotic therapy to prevent or treat gingivitis and periodontitis. Oral administration of probiotics is an effective adjunct in reducing pathogenic bacteria and improving clinical signs of disease. Probiotics may serve as adjunct or replacement therapy substitute antibiotics in managing human periodontal infections in future.

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Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity

Cited by 248 publications

References 45 publications

Role of Probiotics on Oral Health - A Randomized, Double Blind, Placebo-Controlled Microbiological Study

Role of Probiotics on Oral Health - A Randomized, Double Blind, Placebo-Controlled Microbiological Study

Probiotics and Periodontal Disease - A Review

Probiotics and Periodontal Diseases

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