Oral Kaposi's sarcoma in a non-HIV homosexual White male

Kua, Hock; Merchant, W.; Waugh, Michael

doi:10.1258/0956462042395104

Cited by 15 publications

(23 citation statements)

References 4 publications

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“…In another study, 17 Taiwanese patients were reported to have classic KS with lesions in the lower extremities but no immunodeficiency status [5]. KS in HIV‐negative homosexual men has also been described [6,7], and in a retrospective study of 28 men with HIV‐negative KS, the prognosis was good [7]. However, a few cases in HIV‐negative patients manifested as disseminated KS [8–10].…”

Section: Discussionmentioning

confidence: 99%

HIV‐negative disseminated Kaposi's sarcoma in a Taiwanese patient

Huang

Chang

Maa

et al. 2011

The Kaohsiung J of Med Scie

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Kaposi's sarcoma is a common malignancy associated with HIV/AIDS. Herein, we describe the case of a 26-year-old man who presented with bilateral neck and inguinal lymphadenopathy, a massive tumor on the gum, and a nodule over the left eye. A series of tests, including tumor biopsies, were performed, and disseminated Kaposi's sarcoma with human herpesvirus 8 infection was diagnosed. To test for HIV, we used enzyme-linked immunosorbent assay and real-time polymerase chain reaction, but the results were negative. The patient was treated by biweekly intravenous infusion of pegylated liposomal doxorubicin (25 mg/m(2)), and this treatment resulted in a partial response.

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Section: Discussionmentioning

confidence: 99%

HIV‐negative disseminated Kaposi's sarcoma in a Taiwanese patient

Huang

Chang

Maa

et al. 2011

The Kaohsiung J of Med Scie

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“…Its clinical presentation resembles classic KS, with cutaneous involvement, which most commonly occur on the lower limbs but also arms, genitals, and trunk. KS in the HIV‐negative MSM population runs an indolent course similar to classic KS; it is usually chronic, persisting over many years, and presenting as nodules or plaques on the lower extremities . This recently recognized subtype has been termed “nonepidemic KS.”…”

Section: Nonepidemic Ksmentioning

confidence: 99%

“…Three of the patients had KS lesions limited to the legs only, and two patients presented with a single KS lesion on the penis . In 2004, Kua et al reported the case of a 53‐year‐old homosexual man with KS of the buccal mucosa . The patient was observed over a 6‐year period without evidence of HIV, and no other cause of immunodeficiency was identified …”

Section: Nonepidemic Ksmentioning

confidence: 99%

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Epidemiology of Kaposi sarcoma: review and description of the nonepidemic variant

Vangipuram

Tyring

2018

Int J Dermatology

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Kaposi sarcoma (KS) is a rare angioproliferative tumor whose etiology is associated with human herpesvirus 8 (HHV 8). KS lesions typically involve the skin or mucosal surfaces and are characterized by purplish, red-blue, or brown-black macules, papules, and nodules which are prone to bleeding and ulceration. Definitive diagnosis requires biopsy revealing characteristic angioproliferative features. There are four widely recognized types of KS, which are histologically indistinguishable but differ in epidemiology and prognosis. These include classic, endemic, iatrogenic, and epidemic. KS has been increasingly recognized in a new subgroup of patients: men who have sex with men (MSM) but who are HIV-seronegative human immuodeficiency virus-seronegative and have no identifiable immunodeficiency. This fifth variant of KS, termed nonepidemic KS, resembles classic KS in presentation and prognosis. In this literature review, we report the characteristics of nonepidemic KS based on all published cases and highlight the need for clinicians to recognize this new clinical variant.

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“…186 Recrudescent or new KS after HAART may be a sign of IRIS, as may a flare of cutaneous and/or visceral KS. 16 Conjunctival, oral, 187,188 and genital KS can be striking (Figs 11 and 12). Although primary penile KS is uncommon in HIV-negative men, one should consider this possibility when treating nonspecific penile lesions.…”

Section: Clinical Featuresmentioning

confidence: 99%