Oral Health Behaviors, Periodontal Disease, and Pathogens in Preeclampsia: A Case‐Control Study in Korea

Ha, Jong-Chul; Oh, Kyung Joon; Yang, Hye Jin; Jun, Jin Yong; Jin, Bo-Hyoung; Paik, Dai‐Il; Bae, Kyun‐Seop

doi:10.1902/jop.2011.110035

Cited by 21 publications

(21 citation statements)

References 34 publications

(88 reference statements)

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“…Prepregnancy BMI is cited in the literature as a risk factor for preeclampsia 23,41‐44 . This association is also encountered in the present study and underscores the need for females to adjust their weight before becoming pregnant and thereafter control their weight during pregnancy.…”

Section: Discussionsupporting

confidence: 76%

Periodontitis as a Risk Factor for Preeclampsia

Silva

Coutinho

Piscoya

et al. 2012

Journal of Periodontology

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Section: Discussionsupporting

confidence: 76%

Periodontitis as a Risk Factor for Preeclampsia

Silva

Coutinho

Piscoya

et al. 2012

Journal of Periodontology

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“…Only two studies [63], [64] gained the maximum score in the Selection outcome; nine studies [15], [19], [24], [25], [26], [52], [63], [64], [65] had the maximum score in the Comparability outcome; and all studies had a partial score in the Exposure outcome.…”

Section: Resultsmentioning

confidence: 95%

Relationship between Periodontitis and Pre-Eclampsia: A Meta-Analysis

et al. 2013

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BackgroundStudies have suggested controversial results regarding a possible association between pre-eclampsia (PE) and periodontal disease (PD) and no meta-analysis has been performed to clarify this issue.MethodsA literature search of electronic databases was performed for articles published through March 24, 2013, followed by a manual search of several dental and medical journals. The meta-analysis was conducted according to the recommendations of the Cochrane Collaboration and PRISMA. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Heterogeneity was assessed with the χ2-based Cochran Q test and I2 statistic. The level of significance was set at P <0.05.ResultsFifteen studies were included, including three cohort and 12 case-control studies. A positive association was found between PE and PD (OR 2.17, 95% CI 1.38–3.41, P = 0.0008). However, a high and significant heterogeneity was found (χ2 = 62.42, P<0.00001, I2 = 75%). In most cases, subgroup analysis had low power to detect significant differences between PE and non-PE groups.ConclusionBased on the findings of the meta-analysis, PD appears to be a possible risk factor for PE. However, given the important differences in the definitions and diagnoses of PD and PE among the studies, as well as their lack of good methodological quality, future trials are needed to confirm the results of the present meta-analysis.

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“…The individuals with periodontitis were divided into those with generalized and those with localized periodontitis. Generalized periodontitis was defined as four or more interproximal sites with AL ≥4.0 mm not on the same tooth, and localized periodontitis was defined as two or three interproximal sites with AL ≥4.0 mm not on the same tooth 33 …”

Section: Methodsmentioning

confidence: 99%