Oral Graft-Versus-Host Disease

Schubert, Mark M.; Corrêa, Maria Elvira Pizzigatti

doi:10.1016/j.cden.2007.10.004

Cited by 136 publications

(159 citation statements)

References 128 publications

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“…It has been suggested that infl ammation and scarring of the masticatory muscles and the oral mucosa may restrict the oral opening to such an extent that it limits the patient's ability to perform oral hygiene procedures adequately. 4,14 However, in our study patients with GVHD did not report more problems with tooth brushing than HSCT patients without GVHD (Table 6), although there was a near-signifi cant difference towards more severe oral mucosal pain in patients with GVHD after an allogeneic transplantation (Table 6). This observation corroborates studies reporting that GVHD may be associated with higher mucosal sensitivity and painful oral lesions.…”

Section: History Of Gvhd (N = 32)mentioning

confidence: 46%

Xerostomia and chronic oral complications among patients treated with haematopoietic stem cell transplantation

Brand¹,

Bots

Raber-Durlacher

2009

Br Dent J

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Section: History Of Gvhd (N = 32)mentioning

confidence: 46%

Xerostomia and chronic oral complications among patients treated with haematopoietic stem cell transplantation

Brand¹,

Bots

Raber-Durlacher

2009

Br Dent J

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“…Patient parameters that may influence mucositis incidence and severity include age and gender (primarily dependent upon cancer treatment protocol) 57 ; comorbid diseases such as the acquired immunodeficiency syndrome, diabetes, and renal disease; preexisting periodontal disease 58,59 ; genetic factors 60 ; nutritional status; oral microflora; and use of alcohol and/or tobacco. In addition, the use of dental appliances and failure to floss teeth daily have been shown to result in an earlier (although not statistically significant) onset of mucositis.…”

Section: Oral Complications Of Cancer and Cancer Therapymentioning

confidence: 99%

Oral complications of cancer and cancer therapy

Epstein

Thariat

Bensadoun

et al. 2012

CA A Cancer J Clinicians

412

356

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Answer questions and earn CME/CNEOral complications resulting from cancer and cancer therapies cause acute and late toxicities that may be underreported, underrecognized, and undertreated. Recent advances in cancer treatment have led to changes in the incidence, nature, and severity of oral complications. As the number of survivors increases, it is becoming increasingly recognized that the aggressive management of oral toxicities is needed to ensure optimal long‐term oral health and general well‐being. Advances in care have had an impact on previously recognized oral complications and are leading to newly recognized adverse effects. Here, the authors briefly review advances in cancer therapy, including recent advances in surgery, oral care, radiation therapy, hematopoietic cell transplantation, and medical oncology; describe how these advances affect oral health; and discuss the frequent and/or severe oral health complications associated with cancer and cancer treatment and their effect upon long‐term health. Although some of the acute oral toxicities of cancer therapies may be reduced, they remain essentially unavoidable. The significant impact of long‐term complications requires increased awareness and recognition to promote prevention and appropriate intervention. It is therefore important for the primary oncologist to be aware of these complications so that appropriate measures can be implemented in a timely manner. Prevention and management is best provided via multidisciplinary health care teams, which must be integrated and communicate effectively in order to provide the best patient care in a coordinated manner at the appropriate time. CA Cancer J Clin 2012. © 2012 American Cancer Society.

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“…A literatura oferece diversas opções para o tratamento tópico, 11,[81][82][83][84][85][86][87][88][89][90][91][92][93][94] que estão listadas nas Tabelas 9 e 11.…”

Section: Medidas De Prevenção Para O Desenvolvimento E Exacerbação Daunclassified

Diretrizes para o diagnóstico, classificação, profilaxia e tratamento da doença enxerto contra hospedeiro crônica

Bouzas¹,

Silva²,

Tavares³

et al. 2010

Rev. Bras. Hematol. Hemoter.

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Oral Graft-Versus-Host Disease

Cited by 136 publications

References 128 publications

Xerostomia and chronic oral complications among patients treated with haematopoietic stem cell transplantation

Xerostomia and chronic oral complications among patients treated with haematopoietic stem cell transplantation

Oral complications of cancer and cancer therapy

Diretrizes para o diagnóstico, classificação, profilaxia e tratamento da doença enxerto contra hospedeiro crônica

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