Oral focal mucinosis in an adolescent: a case report

Epulis like tumour is a common presentation in the oral cavity and histopathologic revelations range from fibrous hyperplasia to pyogenic granuloma. Oral focal mucinosis is a histopathologic diagnosis based on the presence of myxoid areas. It is a rare presentation in the oral cavity. Etiology is unknown, however the pathogenesis is related to the increased secretion of hyaluronic acid by the fibroblast or myxoid degeneration of connective tissue. Here we report a case of 35 year old woman presenting with a gingival growth in the lower front tooth region and the lesion was clinically diagnosed as fibroma and on histopathologic analysis diagnosed as Oral Focal Mucinosis. We present this case as it is commonly seen on the gingiva and palate and emphasize that histopathologic study is essential to confirm the clinical suspicion. This case contributes to the knowledge of the existing literature and also discusses the histopathologic differential diagnosis of Oral Focal Mucinosis.

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“…OFM affects females more than males and is seen in adults. Some authors have shown its occurrence even in young age as well [8,9] .…”

Section: Discussionmentioning

confidence: 99%

Oral Focal Mucinosis- Presenting as conventional epulis with unconventional histopathology- Revealed by Special stains

Sreelatha¹,

Thomas²,

Varshini³

et al. 2017

Int J Dentistry Res

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“…While the OFM lesion contains a wellcircumscribed, localized area of myxoid connective tissue comprising of ovoid and stellate fibroblasts in an acidophilic stroma. Fibroblasts contain a small amount of cytoplasm and may have been delicate fibrillate processes extending into the surrounding matrix (Lee et al 2012). …”

Section: Discussionmentioning

confidence: 99%

Oral focal mucinosis of gingiva - a rare case report and review of literature

Dabbiru

Naik

Moturi

et al. 2017

IJDR

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Oral focal mucinosis (OFM) is a rare soft-tissue lesion of unknown etiology. Clinically it appears as asymptomatic round lesions and histologically, characterized by focal myxoid degeneration of connective tissue with presence of stellate shaped fibroblasts which were also evident in the present case. This case report stresses on the fact that diagnosis of OFM is almost impossible hence diagnosis should be confirmed by histopathological examination following incisional or excisional biopsy. Through this article we present a rare case of one such lesion on the gingiva and enumerate the most characteristic and myxomatous lesions. Thus though rare, OFM must be considered in the differential diagnosis of soft tissue overgrowths in oral cavity. Here, we describe the clinical and histopathological presentation and subsequent management of OFM in a female patient.

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“…OFM commonly occurs during the fourth to fifth decade of life, and females are more frequently affected than males, with a ratio of almost 2:1 (5) .This lesion appears as an asymptomatic elevated swelling, with the same color of the surrounding normal mucosa, and the mucosa directly overlying bone appears to be the particularly vulnerable (6) . OFM is 1cm or less in diameter (3)(4)(5) . Rarely, the lesion may become secondarily ulcerated (8) .…”

Section: Introductionmentioning

confidence: 99%

Large oral focal mucinosis: a case report

Silva

Monteiro

Norões

et al. 2014

J. Bras. Patol. Med. Lab.

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The aim of this article is to report the case of a 23-year-old female patient that sought dental service for examination of an asymptomatic slow-growing large lump in the mandibular gingiva causing displacement of the right first molar. Excisional biopsy, histopathological analysis, Alcian blue/periodic acid-Schiff (PAS) staining and immunohistochemistry analysis for S-100 were performed. The diagnosis established was oral focal mucinosis. After three years, the patient is still under follow-up, without any recurrences. Although cases of oral focal mucinosis of this particular size are rare, this entity should be considered in the differential diagnosis of oral lesions located in the gingiva.

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Oral focal mucinosis in an adolescent: a case report

Cited by 25 publications

References 8 publications

Oral Focal Mucinosis- Presenting as conventional epulis with unconventional histopathology- Revealed by Special stains

Oral Focal Mucinosis- Presenting as conventional epulis with unconventional histopathology- Revealed by Special stains

Oral focal mucinosis of gingiva - a rare case report and review of literature

Large oral focal mucinosis: a case report

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