Oral colonization by <i>Candida</i> spp. among AIDS household contacts

Milan, Eveline Pı́polo; Kallás, Esper G.; Costa, P. R. de O.; Matta, Daniel Archimedes da; Colombo, Arnaldo Lopes

doi:10.1111/j.1439-0507.2001.00652.x

Cited by 7 publications

(3 citation statements)

References 16 publications

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“…Candida spp. have been isolated from 40 to 60% of healthy mouths, whereas oral candidiasis is more common in immunodeficient individuals, those with severe underlying diseases, and upper denture wearers [3,4]. …”

Section: Introductionmentioning

confidence: 99%

Candida species distribution, genotyping and virulence factors of Candida albicans isolated from the oral cavity of kidney transplant recipients of two geographic regions of Brazil

et al. 2014

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BackgroundCandida albicans is a diploid yeast that in some circumstances may cause oral or oropharyngeal infections. This investigation aimed to study the prevalence of Candida spp. and to analyze the ABC genotypes of 76 clinical isolates of C. albicans obtained from the oral cavity of kidney transplant patients from two distinct geographic regions of Brazil.MethodsWe typed 48 strains with ABC genotyping and Microsatelitte using primer M13 and tested three virulence factors in vitro: phospholipase activity, morphogenesis and the ability to evade from polymorphonuclear neutrophils phagocytosis.ResultsC. albicans was the most prevalent species (86.4%), followed by C. tropicalis (4.5%). C. albicans genotype A was the most prevalent (58 isolates; 76.4%), followed by genotype C (15 isolates; 19.7%) and genotype B (3 isolates; 3.9%). When Microsatellite technique with primer M13 was applied, 80% of the isolates from the South were placed within the same cluster. The majority of Genotype C strains were grouped together within two different clusters. Genotype C was considered more resistant to PMNs attack than genotypes A and B. Strains isolated from the South of Brazil showed also better ability to combat PMNs phagocytosis.ConclusionsWe found a high rate of C. albicans genotype C strains isolated from the oral cavity of this group of patients. This study characterized oral C. albicans strains isolated from kidney transplant recipients and will contribute to a better understanding of the pathogenesis of oral candidiasis.

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Section: Introductionmentioning

confidence: 99%

Candida species distribution, genotyping and virulence factors of Candida albicans isolated from the oral cavity of kidney transplant recipients of two geographic regions of Brazil

et al. 2014

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“…Further epidemiological studies for his environment, such as neighbors, classmates and relatives might be requested. Recently Milan and collaborators (12) reported that Candida spp. colonization was 33% of the AIDS household contacts in contrast with 14% of the HIV-negative control (11,12).…”

Section: Resultsmentioning

confidence: 99%

“…Recently Milan and collaborators (12) reported that Candida spp. colonization was 33% of the AIDS household contacts in contrast with 14% of the HIV-negative control (11,12). C. albicans was the most frequently isolated species.…”

Section: Resultsmentioning

confidence: 99%

Candida dubliniensis in a Brazilian family with an HIV 1- infected child: identification, antifungal susceptibility, drug accumulation and sterol composition

Melo¹,

Taguchi²,

Culhari³

et al. 2006

Braz. J. Microbiol.

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This study investigated the prevalence of C. dubliniensis in a Brazilian family with an HIV -infected child. A total of 42 oral isolates were obtained from eight family members. The identification of C. dubliniensis was performed by polymerase chain reactions (PCR) using primers against a specific sequence of the C. dubliniensis cytochrome b gene. Only the HIV-infected child and his grandmother were colonized by C. dubliniensis. In this study C. dubliniensis isolated from the HIV-infected child exhibited high susceptibility for azoles tested with MICs of 0.125 and 0.5 µg/mL for voriconazole and fluconazole, respectively. Accumulation of [ 3 H] fluconazole in C. dubliniensis isolated from the HIV-infected child was slightly reduced in comparison to the reference susceptible strain. C. dubliniensis isolates had significantly lower ergosterol levels in comparison to C. albicans reference strains.

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The Oral Cavity and Lips

Scully

2004

Rook's Textbook of Dermatology

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Oral colonization by Candida spp. among AIDS household contacts

Cited by 7 publications

References 16 publications

Candida species distribution, genotyping and virulence factors of Candida albicans isolated from the oral cavity of kidney transplant recipients of two geographic regions of Brazil

Candida species distribution, genotyping and virulence factors of Candida albicans isolated from the oral cavity of kidney transplant recipients of two geographic regions of Brazil

Candida dubliniensis in a Brazilian family with an HIV 1- infected child: identification, antifungal susceptibility, drug accumulation and sterol composition

The Oral Cavity and Lips

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