Oral Clefts in the American Indian

Niswander, Jerry D.; Adams, Morton S.

doi:10.2307/4593135

Cited by 23 publications

(12 citation statements)

References 2 publications

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“…These studies show that the British Columbia Indian has a high frequency of oral clefts. This agrees better with Tretsven's findings, than does that (Niswander and Adams, 1967) for the other American Indian groups.…”

Section: Discussionsupporting

confidence: 86%

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Incidence of cleft lip and palate in British Columbia Indians.

Lowry¹,

Renwick²

1969

Journal of Medical Genetics

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Section: Discussionsupporting

confidence: 86%

“…Recently Niswander and Adams (1967) reported a rate of only 1-97 per thousand live births in American Indians. Their study, however, covered a short period of three years and had only one source of ascertainment.…”

Section: Discussionmentioning

confidence: 99%

Incidence of cleft lip and palate in British Columbia Indians.

Lowry¹,

Renwick²

1969

Journal of Medical Genetics

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“…2 A study in California from 1983 to 1992 indentified a cleft lip with or without cleft palate prevalence rate of 1.99 per 1000, including both live and stillbirths from a population-based registry. 3 A survey of 46 designated hospitals in the United States found a cleft lip with or without cleft palate rate of 1.38 per 1000 live births for the years 1963 to 1966, 4 and a statewide review in Montana reported a rate of 3.62 total clefts per 1000 births from 1955 to 1961. 5 Investigations into the rate of orofacial clefts among different ethnic groups have demonstrated less variation in the rate of isolated cleft palate when compared with cleft lip with or without cleft palate, a finding reproduced in this study.…”

Section: The Birth Prevalence Of Cleft Lip and Palate In Canadian Abomentioning

confidence: 99%

“…3 This type of research is limited by the underestimation of the surveillance systems. 4 Despite this, the data collected from the surveillance systems, while not accounting for each country in its entirety, still remain the best available estimate. Another limitation to this type of research is a general lack of uniform collection procedures.…”

Section: Updating the Epidemiology Of Isolated Cleft Palatementioning

confidence: 99%

“…1 Despite the indigenous peoples of North America having some of the highest rates of orofacial clefts in the world, there are few studies on this population, and most of them are limited by small sample sizes. [2][3][4][5] We present a registry-based study to establish an accurate birth prevalence of orofacial clefts in a sample of indigenous peoples of North America.…”

Section: The Birth Prevalence Of Cleft Lip and Palate In Canadian Abomentioning

confidence: 99%

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The Birth Prevalence of Cleft Lip and Palate in Canadian Aboriginal Peoples

Vrouwe¹,

Lowry²,

Olson³

et al. 2013

Plastic and Reconstructive Surgery

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Classification and birth prevalence of orofacial clefts

1998

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To determine the proportion and birth prevalence of "typical" orofacial clefts (cleft lip (CL), cleft palate (CP), cleft lip and palate (CLP)) and "atypical" clefts (median, transversal, or oblique facial clefts) and the conditions in which they occur, we analyzed a population-based sample of 4,433 cases ascertained from 2,509,881 California births. We classified cases into: isolated cleft anomalies, sequences of the primary defect, chromosomal aberrations, monogenic syndromes, results of known teratogens, associations, multiple congenital anomaly (MCA) of unknown etiology, or conjoined twins. The birth prevalence of isolated CL+/-P was 0.77 per 1,000 births (CL 0.29/1,000, CLP 0.48/1,000) and of isolated CP, 0.31 per 1,000 births. Non-Hispanic Whites had the greatest prevalence of isolated clefts, Asians slightly lower prevalences, and Blacks the lowest. Asians had the lowest prevalence of Robin sequence and nonHispanic Whites the highest, twice that of Hispanics. Hispanics, followed by Asians, had the highest prevalence of CL+/-P with MCA; non-Hispanic Whites had the lowest. Asians had the lowest prevalence of CP; in Whites and Hispanics it was almost twice as high. Blacks had the highest CL:CLP ratio, followed by non-Hispanic Whites and Asians; Hispanics had the lowest. Isolated anomalies constituted 61.67% of clefts. In the total sample there were 3.9% sequences, 8.79% chromosomal aberrations, 6.02% monogenic syndromes, 0.2% known teratogens, 0.79% associations, 18.55% MCA of unknown etiology, and 0.1% in conjoined twins. This study supports evaluation of each child on a "case" level, and provides a framework for genetic counseling and other studies focused on causes and prevention of these serious anomalies.

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Oral Clefts in the American Indian

Cited by 23 publications

References 2 publications

Incidence of cleft lip and palate in British Columbia Indians.

Incidence of cleft lip and palate in British Columbia Indians.

The Birth Prevalence of Cleft Lip and Palate in Canadian Aboriginal Peoples

Classification and birth prevalence of orofacial clefts

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