Oral anticoagulant treatment – Evaluating the knowledge of patients admitted in physical medicine and rehabilitation units

Janoly‐Dumenil, Audrey; Bourne, Chris; Loiseau, K.; Luauté, Jacques; Sancho, P.O.; Ciancia, S.; Caillet, F.; Boisson, Dominique; Rioufol, Catherine; Plauchu, M; Rode, Gilles; Jacquin-Courtois, S.

doi:10.1016/j.rehab.2011.02.007

Cited by 17 publications

(17 citation statements)

References 27 publications

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“…Surprisingly, the majority of patients showed knowledge gaps when asked "What to do in case of a missed dose" (item 6), while around one-quarter of patients ignored what happens in case of underdosage or overdosage. A study investigating patient knowledge about warfarin found also that only half of the patients or fewer knew what happens in case of a missed dose, overdosage, or underdosage [30].…”

Section: Discussionmentioning

confidence: 99%

Patient Knowledge about Oral Anticoagulation Therapy Assessed during an Intermediate Medication Review in Swiss Community Pharmacies

et al. 2020

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Background: Therapy with oral anticoagulation (OAC) can be challenging, especially in high risk groups such as chronic patients. Gaps in patient knowledge about OAC are linked to reduced effectiveness and safety of treatment. The objectives of this study were i) to assess OAC knowledge gathered during an intermediate medication review (MR) in patients taking vitamin K antagonists (VKA) or non-vitamin K antagonist oral anticoagulants (NOAC); ii) to assess OAC knowledge two weeks after the MR, and iii) to evaluate patient satisfaction with the MR service in community pharmacies. Methods: Chronic OAC patients were invited for a regular MR service in Swiss community pharmacies, the so-called “Polymedication-Check” (PMC). OAC knowledge was assessed with seven newly generated items asked face-to-face during a PMC and by telephone two weeks later. Knowledge gaps, pharmacists’ spontaneous interventions, and patient satisfaction were documented by observing pharmacy students. Treatment groups were compared. Results: Of all patients (n = 81), the number of patients with one or more knowledge gaps decreased from 66% to 31.3% after PMC (p < 0.001). NOAC patients (n = 31) had more knowledge gaps than VKA patients (n = 50; p < 0.05). Most patients (98.6%) were satisfied with the counselling provided by the pharmacists. Conclusion: The majority of chronic OAC patients shows knowledge gaps. Although spontaneous, the provision of tailored education during a PMC increased patient OAC knowledge.

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Section: Discussionmentioning

confidence: 99%

Patient Knowledge about Oral Anticoagulation Therapy Assessed during an Intermediate Medication Review in Swiss Community Pharmacies

et al. 2020

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“…Patient education about the risks of SM when treated with anticoagulant is crucial. Despite efforts in this area, the knowledge of patients on anticoagulant drugs is still poor 21, thus favouring the occurrence of ADRs caused by DDI.…”

Section: Discussionmentioning

confidence: 99%

Drug interactions related to self‐medication: a French pharmacovigilance database study

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Ghamrawi

et al. 2020

Fundamemntal Clinical Pharma

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Self‐medication (SM) is a common practice perceived by patients as harmless which can, however, entail health risks. The aim of the study was to identify drug–drug interactions (DDIs) involving SM drugs leading to adverse drug reactions (ADRs) in the National French Pharmacovigilance Database. All ADR reports from 1 January 1985 to 31 July 312018, coded as ‘interaction’ and ‘self‐medication’, were selected and studied. Patient characteristics, the level and type of interaction, and the therapeutic classes of the drugs were examined. Adverse drug reactions were analysed and classified according to the system organ classes of the Medical Dictionary for Regulatory Activities. One hundred and three reports totalling 158 ADRs (71% severe cases) were included; 153 DDIs (59.5% pharmacodynamic) involving 234 drugs were identified. The latter included 119 SM drugs (51% available on prescription), mainly analgaesics, anti‐inflammatory drugs, dietary supplements and antibiotics. Haemostasis disorders and renal failure were the most frequently reported ADRs. The analysis of reference documents raised concerns on the lack of information provided by package leaflets. In conclusion, the present study highlights the risks of medically unapproved re‐use of prescription drugs or the consumption of dietary supplements without monitoring possible interactions and ADRs. Patient awareness could be improved by more regular updates of medication package inserts.

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“…[17,23,24] Gras-Champel ve ark. 'nın OAT alan hastaların bilgi dü-zeylerinin düşük olduğuna vurgu yaptıkları çalışmada hastaların %88'inin INR kontrollerine uydukları bildirilmiştir.…”

Section: Discussionunclassified

Assessment of emergency department patients' knowledge on oral anticoagulation therapy

et al. 2011

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SUMMARY Objectives The aim of this study was to assess current knowledge of patients receving oral anticoagulant therapy (OAT). Methods Patients ÖZET AmaçBu çalışmanın amacı, herhangi bir nedenle oral antikoagülan tedavi (OAT) alan hastaların tedavileriyle ilgili bilgilerinin ve ilişkili faktör-lerin değerlendirilmesidir. Gereç ve YöntemBu anket çalışmasında, erişkin acil servise başvuran ve OAT aldığı saptanan hastalardan ankete katılmayı kabul edenlere çalışmacılar tarafından hazırlanan anket uygulandı. Demografik özellikler, ilaç bilgisi ve OAT tedavisiyle ilgili bilgilendirilme durumları incelendi. OAT bilgisine etkili faktörlerin karşılaştırılmasında ki-kare testi kullanıldı. BulgularÇalışmaya katılan 122 hastanın yaş ortalaması 64±14, %37.7'si erkek, %51.6'sı >65 yaş, %33.6'sı hiç öğrenim görmemişti. Hastaların %61.5'i (n=75) OAT ile kanama riski olduğunu, %70.5'inin (n=86) düzenli kan tetkiki yaptırması gerektiğini bildiği saptandı. Çalışma grubunun %15.6'sı (n=19) OAT'nin diğer ilaçlarla, %10.7'si (n=13) yiyeceklerle etkileşimi olduğunu biliyordu. Hastaların %64.8'i (n=79) daha önce OAT konusunda bilgilendirildiğini bildirdi. OAT' yi reçete eden hekim hastaların %27'sinde (n=33) bilgi kaynağı olarak saptandı. Altmış beş yaş ve altı ile 65 yaş üstü hastalar arasında kanama riski (p=0.002) bilgisinde fark bulundu. Öğrenim görmüş olan ve olmayan hastalar arasında kanama riski (p=0.011), ilaç etkileşimi (p=0.049) ve diyet etkileşimi (p=0.034) bilgisinde fark saptandı. Daha önce OAT konusunda bilgilendirilmiş hastalar ile bilgilendirilmemiş hastalar arasın-da kanama riski (p<0.001), tetkik gerekliliği (p<0.001) bilgisi arasında fark bulunmasına rağmen ilaç etkileşimi (p=0.095) ve yiyecek etkileşimi (p=0.54) bilgisi arasında fark bulunmadı. SonuçOral antikoagülan tedavi başarısızlığının komplikasyonları göz önü-ne alındığında OAT bilgi ve bilgilendirilme düzeyleri düşük bulunmuştur. Hekim ve hastaların OAT bilgi düzeylerinin arttırılması gerektiğini düşünüyoruz.

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Oral anticoagulant treatment – Evaluating the knowledge of patients admitted in physical medicine and rehabilitation units

Abstract: These results suggest that specific drug therapy management sessions should be developed as part of PM&R's therapeutic education programs for patients.

Cited by 17 publications

References 27 publications

Patient Knowledge about Oral Anticoagulation Therapy Assessed during an Intermediate Medication Review in Swiss Community Pharmacies

Patient Knowledge about Oral Anticoagulation Therapy Assessed during an Intermediate Medication Review in Swiss Community Pharmacies

Drug interactions related to self‐medication: a French pharmacovigilance database study

Assessment of emergency department patients' knowledge on oral anticoagulation therapy

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