Drug interactions related to self‐medication: a French pharmacovigilance database study

Vacher, Robin; Lagarce, Laurence; Ghamrawi, Sarah; Laugier-Castellan, Delphine; Vial, Thierry; Bagheri, Haleh; Babin, Marina; Briet, Marie

doi:10.1111/fcp.12546

Cited by 12 publications

(15 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In one study, 16.3% (No: 212) of self-medicating students developed side effects [13]. In another study, drug poisoning due to the simultaneous consumption of multiple drugs led to brain hemorrhage and ultimately death of an individual [12]. In this regard, arbitrary violation of the medications' instruction of use can be dangerous.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Nursing students’ perceived consequences of self-medication: a qualitative study

et al. 2020

View full text Add to dashboard Cite

Background: Self-medication associates with many problems and complications, and is considered as a global health issue. Regarding a lack of information about perception of nursing students, as a part of healthcare workers, in this issue, the current study was aimed to explore the perceived consequences of self-medication from the perspective of nursing students. Methods: This qualitative study was conducted using semi-structured individual face-to-face interviews. Purposeful sampling method was used for selection of participants. Twelve nursing students in the age range of 21-36 years were enrolled. Five participants were male and seven were female, seven master's degree and five were undergraduate of bachelor degree. Data were collected using semi-structured interviews and analyzed as content analyses. Results: Two categories and seven sub-categories were emerged from the data analysis. The main categories included; positive consequences and negative consequences, and subcategories included; time saving, cost savings, disease treatment, harming the health system, drug resistance, physical complications and death. Conclusion: The participants believed that self-medication has some positive and negative consequences in viewpoints of nursing students. Regarding, Self-medication that potentially has dangerous consequences, it is suggested the students will be educated and warned about the adverse effects of self-medication, and the nursing teachers should try to rectify students' misconceptions about self-medication.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The unreasonable use of medication can even lead to death. One study showed that, the simultaneous and arbitrary use of multiple medications causes some disorders in hemostasis, renal function, hemorrhagic stroke and death [12]. In another study, 32.3% of students, who had self-medication, developed side effects [13].…”

mentioning

confidence: 99%

Nursing students’ perceived consequences of self-medication: a qualitative study

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Reasons for missing a potential DDI may be a lack of knowledge about DDIs, a lack of appropriate CDSS in the information system they are using, or due to missing correct information about a patient's current medications, or due to different perceptions about responsibility or lack of time to check for interactions [27][28][29]. DDIs can also occur because of the patient's self-medication, such as Over the Counter (OTC) medications or herbal drugs that patients buy themselves, or because of medically unapproved re-use of prescription drugs or the consumption of dietary supplements [30]. There is a need to increase awareness among patients regarding DDIs, especially related to self-medication [30,31].…”

Section: Introductionmentioning

confidence: 99%

“…DDIs can also occur because of the patient's self-medication, such as Over the Counter (OTC) medications or herbal drugs that patients buy themselves, or because of medically unapproved re-use of prescription drugs or the consumption of dietary supplements [30]. There is a need to increase awareness among patients regarding DDIs, especially related to self-medication [30,31]. Written medication information to patients, such as a patient information leaflets (PIL) and online information sources, sometimes include DDI information [32].…”

Section: Introductionmentioning

confidence: 99%

Current Knowledge about Providing Drug–Drug Interaction Services for Patients—A Scoping Review

et al. 2021

View full text Add to dashboard Cite

Drug–drug interactions (DDIs) pose a major problem to patient safety. eHealth solutions have the potential to address this problem and generally improve medication management by providing digital services for health care professionals and patients. Clinical decision support systems (CDSS) to alert physicians or pharmacists about DDIs are common, and there is an extensive body of research about CDSS for professionals. Information about DDIs is commonly requested by patients, but little is known about providing similar support to patients. The aim of this scoping review was to explore and describe current knowledge about providing digital DDI services for patients. Using a broad search strategy and an established framework for scoping reviews, 19 papers were included. The results show that although some patients want to check for DDIs themselves, there are differences between patients, in terms of demands and ability. There are numerous DDI services available, but the existence of large variations regarding service quality implies potential safety issues. The review includes suggestions about design features but also indicates a substantial knowledge gap highlighting the need for further research about how to best design and provide digital DDI to patients without risking patient safety or having other unintended consequences.

show abstract

“…Prescribers often do not have access to all prescriptions made by other HCP due to lack of interoperability between different EHRs [35]. Patients also use OTC (over the counter drugs, available without prescription) and herbal remedies on their own, which are not on their medication list [36]. Besides the challenge of lack of overview of a patient's medication, prescribers' knowledge of clinically relevant DDI may vary and there is need for support systems to identify DDI and adjust inappropriate combinations [3,7,34].…”

Section: Introductionmentioning

confidence: 99%

Patients’ Use and Perceptions of a Drug-Drug Interaction Database: A Survey of Janusmed Interactions

Justad¹,

Askfors²,

Shemeikka³

et al. 2021

Pharmacy

View full text Add to dashboard Cite

Janusmed interactions is a drug-drug interactions (DDI) database available online for healthcare professionals (HCP) at all levels of the healthcare system including pharmacies. The database is aimed at HCP but is also open to the public for free, for those individuals who register for a personal account. The aim of this study was to investigate why and how patients use the database Janusmed interactions, how they perceive content and usability, and how they would react if they found an interaction. A web-based questionnaire was sent by email to all users who had registered for Janusmed interactions as a “patient” (n = 3219). A total of 406 patients completed the survey (response rate 12.6%). The study shows that there is an interest among patients to use a DDI database to check their own or a relative’s medication. The respondents found the database easy to use and perceive they understand the information aimed at HCP. Most patients stated they would talk to their HCP if they found an interaction and not adjust their treatment by themselves. However, the respondents in this study are actively searching for information and seem to have high health literacy. Thus, the findings are not generalizable for the general population.

show abstract

Drug interactions related to self‐medication: a French pharmacovigilance database study

Cited by 12 publications

References 21 publications

Nursing students’ perceived consequences of self-medication: a qualitative study

Nursing students’ perceived consequences of self-medication: a qualitative study

Current Knowledge about Providing Drug–Drug Interaction Services for Patients—A Scoping Review

Patients’ Use and Perceptions of a Drug-Drug Interaction Database: A Survey of Janusmed Interactions

Contact Info

Product

Resources

About