Oral and Maxillofacial Fungal Infections

Manfredi, Maddalena; Polonelli, Luciano; Giovati, Laura; Alnuaimi, Ali; McCullough, Michael

doi:10.1007/978-3-319-72303-7_1

Cited by 6 publications

(4 citation statements)

References 213 publications

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“…Diagnosis of OC is mainly based on clinical sign and symptoms in association with medical history of the patient: however, in immunocompromised patients, where fungal infections tend to recur and become chronic, the microbiological evaluation of the Candida spp involved, as well as their susceptibility to antifungal treatment, may be of help in the management of these infections, avoiding the emergence of resistant strains (22).…”

Section: Opportunistic Fungal Infectionsmentioning

confidence: 99%

Oral infections in oral cancer survivors: A mini-review

Pispero

Lombardi²,

Manfrēdi³

et al. 2022

Front. Oral. Health

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The oral cancer survivors are a group of special individuals whose disease affect anatomical structures with a key role in identity and communication and a fundamental role in basic human functions such as speaking, eating, swallowing and breathing. Thus, quality of life of these individuals can be impaired by the consequences of disease and treatments, in particular surgery and radiotherapy. Among others, infectious conditions of any nature, bacterial, viral, fungal, are a frequent finding among oral cancer survivors. In fact, the peculiar systemic and local conditions of these subjects are known to significantly modify the microbiota, which, besides facilitating opportunistic infections, can affect the cancer microenvironment, as well as alter the effects of the anti-cancer therapies. Similarly, mouth infections can also affect the prognosis of oral cancer survivors. Among the opportunistic infections, fungal are the most common infections affecting these subjects, since neutropenia resulting from cancer, as well as chemotherapy and/or radiotherapy treatments, promote the shift from the carrier state of Candida species, to pathogen state. Treatment of oral candidiasis can be difficult in oral cancer survivors, and good evidence supports clotrimazole as the most effective for prevention, and fluconazole as the one with the best risk-benefit profile. Probiotics, although promising, need better evidence to be considered an effective treatment or preventive measure.

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Section: Opportunistic Fungal Infectionsmentioning

confidence: 99%

Oral infections in oral cancer survivors: A mini-review

Pispero

Lombardi²,

Manfrēdi³

et al. 2022

Front. Oral. Health

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“…The mechanism by which conventional cigarette smoking induces oral candidiasis is not yet fully understood, but a plausible theory has emerged suggesting that smoking causes reduced saliva flow, and thus a decrease in oral pH, which favours the colonization and growth of Candida. Manfredi et al suggested that cigarette smoking may cause a decrease in immunoglobulin A (IgA) in saliva and inhibit neutrophil activity, promotthe oral colonization of Candida [73].…”

Section: Bms (Burning Mouth Syndrome)mentioning

confidence: 99%

“…Absorption disorders and states of eating disorders are also important in cases of the development of candidiasis; in particular, a diet rich in carbohydrates contributes to its development, and deficiencies of iron, zinc, magnesium, selenium, folic acid and vitamins (A, B6, B12 and C) induce the development of this disease [73].…”

Section: Bms (Burning Mouth Syndrome)mentioning

confidence: 99%

The most common oral cavity ailments in geriatric patients

Bijowski¹,

Dąbrowska²,

Onopiuk³

et al. 2021

Med Og Nauk Zdr.

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Introduction. Demographic forecasts for the Polish population indicate that in 2030 in Poland, that the elderly will constitute approximately 24% of the population. Functional dentition and providing physiological and social benefis are part of the physical and mental well-being of an elderly patient with missing dentition and general diseases. Objective. The aim of the study is to discusses the most common ailments encountered in geriatric patients treated by dentists. Etiology, characteristics and treatment options for the described ailments are taken into account. In dental treated patients age over 60, the most common problems encountered are: stomatopathies, xerostomia and burning mouth syndrome (BMS). Stomatopathies werethe most common in diabetic patients, and in patients using removable or fixed prosthetic restorations. Materials and method. Analysis of the assumed aims of the paper was carried out based on the available literature. Particular attention was paid to the most common complaints in elderly patients. Conclusions. All the above-listed oral cavity health conditions affect the well-being, i.e. physical and mental health of a patient. Local pathological states, such as prosthetic stomatopathies, pass mainly by eliminating the cause of contact inflammation. Other ailments: periodontitis, BMS or xerostomia, are closely related to the general condition of the patient. Changes in the oral cavity depend on the intensity and stabilization of the general disease. His is the reason that a very important role is played by the attending physicians: diabetologists, neurologists or psychiatrists. The cooperation of a dentist with a general practitioner can significantly improve the health of geriatric patients.

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“…As lesões são geralmente múltiplas, simétricas, e podem apresentar uma variedade de formas, incluindo máculas, pápulas, ou placas brancas. Muitas vezes, essas lesões são acompanhadas por outros sintomas sistêmicos da sífilis, incluindo febre e mal-estar (MANFREDI et al, 2019).…”

Section: Introductionunclassified

Sífilis: compreensão e manejo das manifestações orais

Dedino,

Fernandes,

Zardeto

et al. 2023

Cad. Pedagógico

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Este trabalho tem como objetivo realizar uma revisão da literatura a fim de elucidar as complexidades da sífilis, suas vias de transmissão, manifestações clínicas variadas em cada estágio da doença, destacando a importância de um diagnóstico preciso para um manejo clínico eficaz das lesões orais que podem ocorrer. A sífilis é uma doença sexualmente transmissível grave causada pelo Treponema pallidum, que pode apresentar sintomas diversificados e evoluir em estágios distintos: primário, secundário, latente e terciário. As manifestações clínicas variam consideravelmente, com o estágio inicial marcado por uma úlcera indolor conhecida como "cancro duro", e o estágio secundário apresentando lesões mucocutâneas e sintomas sistêmicos. É crucial destacar que a doença tem uma taxa crescente de incidência global, o que é alarmante considerando sua transmissão vertical que pode resultar em natimortos e mortes neonatais. No Brasil, as estatísticas mostram uma tendência de aumento dos casos, elevando a importância do diagnóstico precoce e gestão eficaz, particularmente através do reconhecimento de manifestações orais comuns nos estágios iniciais da doença. Essas manifestações podem ser um indicativo crucial de infecção, ressaltando o papel vital dos dentistas no processo de diagnóstico. Os profissionais de saúde precisam estar cientes das variadas apresentações clínicas da sífilis para facilitar o diagnóstico precoce e o manejo eficiente, particularmente em relação às lesões orais que podem ocorrer em diversos estágios da doença. A consciência e educação sobre a prevenção da sífilis também são essenciais, dados os desafios apresentados pelo aumento da incidência e da complexidade da doença.

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Oral and Maxillofacial Fungal Infections

Cited by 6 publications

References 213 publications

Oral infections in oral cancer survivors: A mini-review

Oral infections in oral cancer survivors: A mini-review

The most common oral cavity ailments in geriatric patients

Sífilis: compreensão e manejo das manifestações orais

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