OR17. Clinical characteristics and risk factors of reduced ejection fraction in coronary artery disease patients undergoing percutaneous coronary intervention at sanglah hospital denpasar, bali, indonesia in 2021: a cross-sectional hospital-based study

Abstract

Aims This study was conducted to determine the clinical characteristics and risk factors of reduced ejection fraction (EF) in coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI). Methods and Results Analytical observational study with a cross-sectional study design was conducted. All patients diagnosed with CAD and had a history of PCI at Sanglah Hospital from December 2020 – June 2021 were enrolled. Univariate analysis was performed to demonstrate the baseline characteristics of the patients. Chi-Square analysis was performed to determine the association between variables. Kruskal-Wallis analysis was performed to determine the differences in clinical characteristics between groups of patients based on the EF. There were 196 patients included in this study. Most of the patients were male (n = 135, 68.9%), with median age of 59 (22-81). The median of the EF was 59.2% (22-81). The most common comorbid found in the patients was hypertension (n = 108, 55.1%). Chi-Square analysis showed a significant association between hyperuricemia (p = 0.019; PR = 1.815; 95%CI= 1.163-2.831), arrhythmias (p = 0.002; PR = 2.271; 95%CI=1.491-3.459), and cardiomegaly (p = 0.011; PR = 1.722; 95%CI=1.151-2.577) with the reduced EF. In logistic regression analysis, arrhythmia (p = 0.009; PR = 4.191; 95%CI=1.426-12.320) was significantly associated with reduced EF. Kruskal-Wallis analysis showed a significant difference in white blood cell (p = 0.021), neutrophil (p = 0.027), and serum glutamic pyruvic transaminase (p = 0.013) in patients based on the EF. Conclusion The comorbidity of CAD had a significant association with the reduced EF. Early intervention against this factor can improve the quality of management in the patient.

Analysis of Health-Seeking Behavior Factors in Coronary Heart Disease Patients

“…East Java ranks 4th with the most CHD sufferers in Indonesia. Data from the Indonesian Ministry of Health stated that the prevalence of coronary heart disease in East Java based on a doctor's diagnosis was 0.5% or around 144,279 sufferers (Upadhana et al, 2021). Based on the results of a preliminary study conducted by researchers at several Puskesmas in Gresik, coronary heart disease is included in the top 10 most diseases registered at the Puskesmas.…”

“…Distance and cost of health service providers, attitudes, perceptions and lack of knowledge are the main obstacles for patients in determining the right treatment. The doctor's diagnosis is 0.5% or around 144,279 sufferers (Upadhana et al, 2021). Based on the results of a preliminary study conducted by researchers at several health centres in Gresik.…”