“…To date, a number of new biomedical applications have been achieved by using MCAs. [30][31][32][33][34][35] Pharmacokinetics is an important parameter used to study the movement of foreign substances (mostly the drugs) into, through and out of the organism, which includes the processes of liberation, absorption, distribution, metabolization and excretion. Recently, Xiao et al utilized MSOT to investigate the pharmacokinetics of HypoxiSense 680 (HS680), a commercially available and tumor-targeted MCA, in a mouse xenograft model of breast cancer (Fig.…”