Optimizing correction of coma aberration in keratoconus with a novel soft contact lens

Suzaki, Asaki; Koh, Shizuka; Maeda, Naoyuki; Asonuma, Sanae; Santodomingo-Rubido, Jacinto; Oie, Yoshinori; Soma, Takeshi; Fujikado, Takashi; Nishida, Kohji

doi:10.1016/j.clae.2020.12.071

Cited by 4 publications

(6 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All anterior corneal wavefront values showed improvement in the central area of 4.5 mm along with a significant visual recovery in our patients, despite increased peripheral aberrations at 7.00 mm. The improvements in anterior corneal aberrations achieved with CSKL fitting were quite remarkable and comparable to previous studies [8,21,24] . At 4.5 mm, all corneal aberrations, including LOAs and HOAs, showed significant reductions.…”

Section: Discussionsupporting

confidence: 87%

“…Our results suggest that CSKL fitting improved visual acuity in the majority of our study population by controlling HOAs in the central optical zones. Several studies have shown that soft CLs can be beneficial in correcting HOAs in severely aberrated eyes and provide visual benefits over their use in normal eyes [8,[21][22] . To our knowledge, this is the first study to investigate the role of pupil size on the occurrence of photic discomfort rates with CSKL in KC patients.…”

Section: Discussionmentioning

confidence: 99%

“…However, several studies showed that residual HOAs persist even with RGP CLs oneye, which are typically attributed to the posterior corneal surface [6][7] . In recent years, the custom-made soft keratoconus lenses (CSKLs) have been proposed as a practical and comfortable solution for correcting ocular HOAs in eyes with irregular corneas [8][9][10] . HydroCone or Toris K lenses are specially designed soft silicone hydrogel toric lenses for KC, with front toric surface and spherical back optic zones.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Efficacy of custom-made soft keratoconus lenses on corneal aberrations and photic phenomena in patients with keratoconus: a corneal topography imaging based study

Penbe¹,

Arsan²,

Kurna³

2023

Int J Ophthalmol

View full text Add to dashboard Cite

AIM: To evaluate the efficacy of custom-made soft keratoconus (KC) lenses on corneal aberrations and photic phenomena in two different optical zones in patients with KC. METHODS: Sixty eyes of 42 patients with KC were examined at baseline and after fitting HydroCone (Toris K) soft silicone hydrogel lenses. Best spectacle-corrected visual acuity (BSCVA) and contact lens-corrected visual acuity (CLCVA) were recorded. Lower- and higher-order corneal aberrations (LOAs and HOAs) were measured with and without Toris K lenses and compared in central 4.5 mm and 7 mm zones. Mesopic pupil diameter and subjective photic phenomena were also assessed. RESULTS: Mean CLCVA was significantly improved compared to BSCVA (P<0.0001). Corneal curvature and refractive measurements were found to be significantly reduced by the use of Toris K lenses, except for posterior corneal curvature values. In the 4.5 mm central optical zone, all wavefront aberrations decreased significantly after lens fitting (P<0.0001). In contrast, in the 7 mm (peripheral) optical zone, values for HOAs, spherical and residual aberrations, and optical path differences were increased, while LOAs, trefoil, and quadrifoil coefficients were decreased. The rate of photic phenomena was significantly higher in participants with a pupil size >6.00 mm (85.7%). CONCLUSION: Toris K lenses provide good visual results and a significant reduction in central corneal aberrations in patients with KC but could cause an increase in peripheral aberrations. This practical and nonsurgical approach appears to be an effective method for the visual management of KC.

show abstract

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy of custom-made soft keratoconus lenses on corneal aberrations and photic phenomena in patients with keratoconus: a corneal topography imaging based study

Penbe¹,

Arsan²,

Kurna³

2023

Int J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Lens centration is a major factor that affects the clinical performance of aberration-controlled contact lenses, with visual performance decreasing when the decentration exceeds 0.5 mm [334]. More recently, a different approach has been proposed that utilises a standardised soft lens fitting set with several different vertically asymmetric powers and axes, in a similar manner to soft toric contact lens fitting [333,335]. Using this approach, a prototype soft contact lens design successfully corrected vertical coma and improved quality of vision in keratoconus patients [333].…”

Section: Soft Contact Lensesmentioning

confidence: 99%

“…Using this approach, a prototype soft contact lens design successfully corrected vertical coma and improved quality of vision in keratoconus patients [333]. Further enhancements to this approach included optimisation of the optic zone relative to the pupil centre, which resulted in further improvements of the correction of coma aberrations and overall visual performance [335]. Reverse geometry soft contact lens designs have also been used for keratoconus correction [251,321,331,336].…”

Section: Soft Contact Lensesmentioning

confidence: 99%

Keratoconus: An updated review

Santodomingo-Rubido

Carracedo

Suzaki

et al. 2022

Contact Lens and Anterior Eye

Self Cite

215

112

View full text Add to dashboard Cite

Keratoconus is a bilateral and asymmetric disease which results in progressive thinning and steeping of the cornea leading to irregular astigmatism and decreased visual acuity. Traditionally, the condition has been described as a noninflammatory disease; however, more recently it has been associated with ocular inflammation. Keratoconus normally develops in the second and third decades of life and progresses until the fourth decade. The condition affects all ethnicities and both sexes. The prevalence and incidence rates of keratoconus have been estimated to be between 0.2 and 4,790 per 100,000 persons and 1.5 and 25 cases per 100,000 persons/year, respectively, with highest rates typically occurring in 20-to 30-year-olds and Middle Eastern and Asian ethnicities. Progressive stromal thinning, rupture of the anterior limiting membrane, and subsequent ectasia of the central/paracentral cornea are the most commonly observed histopathological findings. A family history of keratoconus, eye rubbing, eczema, asthma, and allergy are risk factors for developing keratoconus. Detecting keratoconus in its earliest stages remains a challenge. Corneal topography is the primary diagnostic tool for keratoconus detection. In incipient cases, however, the use of a single parameter to diagnose keratoconus is insufficient, and in addition to corneal topography, corneal pachymetry and higher order aberration data are now commonly used. Keratoconus severity and progression may be classified based on morphological features and disease evolution, ocular signs, and index-based systems. Keratoconus treatment varies depending on disease severity and progression. Mild cases are typically treated with spectacles, moderate cases with contact lenses, while severe cases that cannot be managed with scleral contact lenses may require corneal surgery. Mild to moderate cases of progressive keratoconus may also be treated surgically, most commonly with corneal crosslinking. This article provides an updated review on the definition, epidemiology, histopathology, aetiology and pathogenesis, clinical features, detection, classification, and management and treatment strategies for keratoconus.

show abstract