Optimization the Effects of Physicochemical Parameters on the Degradation of Cephalexin in Sono-Fenton Reactor by Using Box-Behnken Response Surface Methodology

Al-Musawi, Tariq J.; Kamani, Hossein; Bazrafshan, Edris; Panahi, Ayat Hossein; Silva, Marcela Fernandes; Abi, Gholamreza

doi:10.1007/s10562-019-02713-x

Cited by 64 publications

(13 citation statements)

References 46 publications

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“…Many optimization processes have been introduced previously, including maximum central composite, Doehlert, and Box-Behnken design. However, in most cases, the Box-Behnken has achieved perfectly three levels optimized per factor with fewer experimental data points, and output efficiency has been shown to fit extremely well as compared with experimental results (Ferreira et al 2007;Al-Musawi et al 2019). The operating variables were assessed by analysis of variance (ANOVA), and various variables can be understood from the 3D surface plot.…”

Section: Introductionmentioning

confidence: 99%

Glyphosate adsorption by Eucalyptus camaldulensis bark-mediated char and optimization through response surface modeling

2019

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In this study, orthophosphoric acid-modified activated char was prepared from Eucalyptus camaldulensis bark (EBAC), and used for removing traces of [N-(phosphonomethyl)glycine] (glyphosate) herbicide from aqueous solution. The adsorption capacity was characterized by zero-point-charge pH, surface analysis, and Fourier transform infrared spectroscopy. Batch mode experiments were conducted to observe the effects of selected variables, namely dose, contact time, pH, temperature, and initial concentration, on adsorption capacity. Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich isotherm models were generated to describe the mechanisms involved in the multilayer adsorption process. The results show that high temperature enhanced the adsorption capacity of EBAC, with a temperature of 373 K yielding adsorption capacity (q max) and Freundlich parameter (K F) of 66.76 mg g −1 and 9.64 (mg g −1) (L mg −1) −n , respectively. The thermodynamics study revealed entropy and enthalpy of −5281.3 J mol −1 and −20.416 J mol −1 , respectively. Finally, glyphosate adsorption was optimized by the Box-Behnken model, and optimal conditions were recorded as initial concentration of 20.28 mg L −1 , pH 10.18, adsorbent dose of 199.92 mg/50 mL, temperature of 303.23 K, and contact time of 78.42 min, with removal efficiency of 98%. Therefore, it can be suggested that EBAC could be used as an efficient, low-cost adsorbent for removal of glyphosate from aqueous solutions.

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Section: Introductionmentioning

confidence: 99%

Glyphosate adsorption by Eucalyptus camaldulensis bark-mediated char and optimization through response surface modeling

2019

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“…The F-values > 0.001 (975.81, 6.47 and 62.10) and p-values < 0.05 obtained for D % MB , k app MB and I uLog EC responses confirming the qualification of the model to predict the decolorization of MB (D % MB and k app MB ) and the inactivation of E. coli K12 (I uLog EC ) by the Fenton reaction. In addition, the validity of the model is confirmed by the p-value of the lack of fit with values greater than the lowest limit of fit as recommended (>0.05) [32]. As a result, the models developed in this work for predicting the D % MB , k app MB and I uLog EC by the Fenton process were considered adequate.…”

Section: Models and Regression Analysismentioning

confidence: 56%

Optimization of Fenton Technology for Recalcitrant Compounds and Bacteria Inactivation

2020

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In this work, the Fenton technology was applied to decolorize methylene blue (MB) and to inactivate Escherichia coli K12, used as recalcitrant compound and bacteria models respectively, in order to provide an approach into single and combinative effects of the main process variables influencing the Fenton technology. First, Box–Behnken design (BBD) was applied to evaluate and optimize the individual and interactive effects of three process parameters, namely Fe2+ concentration (6.0 × 10−4, 8.0 × 10−4 and 1.0 × 10−3 mol/L), molar ratio between H2O2 and Fe2+ (1:1, 2:1 and 3:1) and pH (3.0, 4.0 and 5.0) for Fenton technology. The responses studied in these models were the degree of MB decolorization (D%MB), rate constant of MB decolorization (kappMB) and E. coli K12 inactivation in uLog units (IuLogEC). According to the results of analysis of variances all of the proposed models were adequate with a high regression coefficient (R2 from 0.9911 to 0.9994). BBD results suggest that [H2O2]/[Fe2+] values had a significant effect only on D%MB response, [Fe2+] had a significant effect on all the responses, whereas pH had a significant effect on D%MB and IuLogEC. The optimum conditions obtained from response surface methodology for D%MB ([H2O2]/[Fe2+] = 2.9, [Fe2+] = 1.0 × 10−3 mol/L and pH = 3.2), kappMB ([H2O2]/[Fe2+] = 1.7, [Fe2+] = 1.0 × 10−3 mol/L and PH = 3.7) and IuLogEC ([H2O2]/[Fe2+] = 2.9, [Fe2+] = 7.6 × 10−4 mol/L and pH= 3.2) were in good agreement with the values predicted by the model.

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“…3 a, ionic forms of CPX (at pH 3.0 and 9.0), favor its removal, while a more stable nature (zwitterionic form) could imply less reactivity and an eventual lower oxidation. The primary attacks of HO• to CPX molecule could occur on three sites: 1) the β-lactam ring, which is a highly reactive site because the ring is very strained and the carbonyl-nitrogen bond is very labile (hydroxylation reaction); 2) the aromatic ring, which typically experiences electrophilic substitutions; 3) and in the secondary amide moiety, whose reactivity towards oxidants can be favored through the inductive and resonant effects generated by the substituents (oxidative reaction), besides, by the charge level in the medium [34] , [35] , [36] .…”

Section: Resultsmentioning

confidence: 99%

Elimination of cephalexin and doxycycline under low frequency ultrasound

Sierra

Zúñiga-Benítez

Peñuela

2021

Ultrasonics Sonochemistry

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Optimization the Effects of Physicochemical Parameters on the Degradation of Cephalexin in Sono-Fenton Reactor by Using Box-Behnken Response Surface Methodology

Cited by 64 publications

References 46 publications

Glyphosate adsorption by Eucalyptus camaldulensis bark-mediated char and optimization through response surface modeling

Glyphosate adsorption by Eucalyptus camaldulensis bark-mediated char and optimization through response surface modeling

Optimization of Fenton Technology for Recalcitrant Compounds and Bacteria Inactivation

Elimination of cephalexin and doxycycline under low frequency ultrasound

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