Optimization of ultrasound-assisted extraction of natural antioxidants from Piper betle using response surface methodology

Ali, Ameena; Lim, Xiao Y.; Chong, Chien Hwa; Mah, Siau Hui; Chua, Bee Lin

doi:10.1016/j.lwt.2017.11.033

Cited by 81 publications

(62 citation statements)

References 32 publications

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“…Therefore, a study that is based on a Box-Behnken design was carried out to determine the optimal conditions for the extraction method and to evaluate the importance of each factor and the relationships between them [31,32]. The results were treated with a response surface method; a technique that generates a mathematical model where the response of the system can be observed in terms of the factors that are involved and the interactions between them [23,33].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Ultrasound Assisted Extraction as an Alternative Method for the Extraction of Anthocyanins and Total Phenolic Compounds from Maqui Berries (Aristotelia chilensis (Mol.) Stuntz)

et al. 2019

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Research interest regarding maqui (Aristotelia chilensis) has increased over the last years due to its potential health benefits as one of the most antioxidant-rich berries. Ultrasound-assisted extraction (UAE) is an advanced green, fast, and ecological extraction technique for the production of high quality extracts from natural products, so it has been proposed in this work as an ideal alternative extraction technique for obtaining extracts of high bioactivity from maqui berries. In order to determine the optimal conditions, the extraction variables (percentage of methanol, pH, temperature, ratio “sample mass/volume of solvent”, amplitude, and cycle) were analyzed by a Box-Behnken design, in conjunction with the response surface method. The statistical analysis revealed that the temperature and the percentage of methanol were the most influential variables on the extraction of the total phenolic compounds and total anthocyanins, respectively. The optimal extraction time was determined at 15 min for total phenolic compounds, while it was only 5 min for anthocyanins. The developed methods showed a high precision level with a coefficient of variation of less than 5%. Finally, the new methods were successfully applied to several real samples. Subsequently, the results were compared to those that were obtained in previous experiments by means of microwave assisted extraction (MAE). Similar extraction yields were obtained for phenolic compounds under optimized conditions. However, UAE proved to be slightly more efficient than MAE in the extraction of anthocyanins.

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Section: Introductionmentioning

confidence: 99%

Assessment of Ultrasound Assisted Extraction as an Alternative Method for the Extraction of Anthocyanins and Total Phenolic Compounds from Maqui Berries (Aristotelia chilensis (Mol.) Stuntz)

et al. 2019

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“…Response surface methodology (RSM) is a statistical model that has been widely used and implemented on experimental works to provide the optimal experimental factor using multiple extraction parameters (Ali, Lim, Chong, Mah, & Chua, ; Ferreira et al, ). Extraction yield is affected by multiple independent variables such as plant material to solvent ratio, solvent, time, temperature, pressure, and other parameters during the extraction process.…”

Section: Introductionmentioning

confidence: 99%

Optimization of the exhaustive hydrodistillation method in the recovery of essential oil from fresh and cured betel leaves (Piper betleL.) using the Box–Behnken design

Madhumita

Guha

Nag

2019

J Food Process Preserv

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The optimization of extraction by the Box–Behnken design of response surface methodology, chemical composition, antioxidant activity (AA), and total phenolic content (TPC) of fresh and cured betel leaf essential oil (BLEO) was reported. A quadratic polynomial equation developed by multiple regression analysis revealed that the models were highly significant with R2 = .98 and p < .0001. At optimal extraction conditions of extraction time (140 min), extraction temperature (100°C) and leaf to water ratio (1:1.5 g/L), 0.35% and 0.48% of fresh and cured BLEO yield were obtained. Thirty‐three and thirty volatile compounds were identified from fresh and cured BLEO by gas chromatography‐mass spectroscopy, accounting for 96.4% and 93.96% of the total oils, respectively. Eugenol, estragole, linalool, α‐copene, and anethole with different percentages were accounted to be major components. Fresh BLEO exhibited strong antioxidant effects on DPPH and TPC than cured leaf EO. Both the EOs explored that AA had a positive correlation with their phenolic contents. Practical applicationsThe present study explores the effect of optimized exhaustive hydrodistillate condition on the analysis of chemical composition and AA of essential oil (EO). The findings of optimized extraction embodied in the present research can be scaled up for commercial and industrial purposes. Both fresh and cured BLEO may be used in the food industry as a natural food preservative and flavoring agent. It can be also used for various herbal, medicinal, and therapeutic products. The main identified compounds such as eugenol, estragole, and linalool are the most valuable for food and pharmaceutical industries. Eugenol was found to be the highest amount in the extracted EO that can be used as a local anesthetic in dentistry as an ingredient in dental cement for temporary fillings.

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“…bubbles are induced by sound waves, with frequencies above 20 kHz, which cause mechanical 1 vibrations into the plant matrix. These mechanical vibrations, can rupture cell wall tissues 2 ameliorating the penetration of the solvent into the matrix and achieving higher amounts of 3 tannins extracted (Ali et al, 2018).…”

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confidence: 99%

Tannins extraction: A key point for their valorization and cleaner production

Hoyos-Martínez

Merle

Labidi

et al. 2019

Journal of Cleaner Production

145

114

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Tannins are phenolic compounds with considerable abundance in nature. They have attracted significant attention lately owing to their huge variety of potential applications. Accordingly, the tannin-related activity in terms of research has undergone a great boost, especially as green feedstock for materials in several fields. Nevertheless, the extraction process remains as the main bottleneck for their valorization, due to their heterogeneous nature. In the present review, a comprehensive study of the main types of tannins extraction techniques was carried out based on the works from the last 20 years. The literature review was carried through analysis of an initial sample of works followed by snowballing process, obtaining the main extraction parameters of each method. Thereby, the different tannins extraction methods were assessed and their major strengths and weaknesses elucidated. Moreover, a direct comparison between the different techniques was done, leading to the main prospectives for the efficient and clean tannins extraction and production.

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Optimization of ultrasound-assisted extraction of natural antioxidants from Piper betle using response surface methodology

Cited by 81 publications

References 32 publications

Assessment of Ultrasound Assisted Extraction as an Alternative Method for the Extraction of Anthocyanins and Total Phenolic Compounds from Maqui Berries (Aristotelia chilensis (Mol.) Stuntz)

Assessment of Ultrasound Assisted Extraction as an Alternative Method for the Extraction of Anthocyanins and Total Phenolic Compounds from Maqui Berries (Aristotelia chilensis (Mol.) Stuntz)

Optimization of the exhaustive hydrodistillation method in the recovery of essential oil from fresh and cured betel leaves (Piper betleL.) using the Box–Behnken design

Tannins extraction: A key point for their valorization and cleaner production

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