Optimization of ultrasound-assisted extraction of turkish propolis and characterization of phenolic profile, antioxidant and antimicrobial activity

Bakkaloğlu, Zeynep; Arıcı, Muhammet; Karasu, Salih

doi:10.1590/fst.14520

Cited by 16 publications

(20 citation statements)

References 32 publications

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“…Also, propolis extract showed stronger antibacterial activity against the Gr+ bacteria (10 -26.5 mm) than the Gr-bacteria (6 -13.5 mm). Comparable results were found by Bakkaloglu et al (2021). They also reported that ethanol as an extraction solvent provided higher antimicrobial activity for the Turkish propolis extracts in comparison to propylene glycol, dimethyl sulfoxide, and distilled water.…”

Section: Antibacterial Effect Of Propolis Extractmentioning

confidence: 59%

“…Bioactivity of propolis depends on many factors such as geography, season, plant resource, composition and concentration of phenolic compounds, and extraction methodology (Toreti et al, 2013;Rivero-Cruz et al, 2020;Bakkaloglu et al, 2021). It has been noted that Turkish propolis in particular with the presence of wide range of flavonoids (Coskun et al, 2018) and phenolics (Bakkaloglu et al, 2021) has an elevated antioxidant and antimicrobial activity (Ristivojevic et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial and Antioxidant Activities of Commercialized Turkish Propolis Extract, and Application to Beef Meatballs

Gedikoğlu

2022

Turkish JAF Sci.Tech.

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Propolis is a resinous substance produced by bees that is rich with phenolic and flavonoid compounds. Extract of propolis has a high antioxidant and antimicrobial properties due to the presence of these compounds. Therefore, the main objectives of this study were to examine the antibacterial and the antioxidant activities of standardized, commercial water extract of propolis in vivo assays, and to assess its impact on preservation of raw beef meatballs aerobically packaged and stored at 4ºC for 7 days. The results showed that the propolis extract demonstrated the highest antibacterial activity against Staphylococcus epidermidis in vivo test. Furthermore, meatballs prepared with the propolis extract had an extended shelf life about a week in comparison to the regular meatballs. Besides, the propolis extract was a very effective natural antioxidant agent for controlling the oxidative changes in meatballs. The propolis treatment provided 64.6% reduction in the malondialdehyde formation at the final day of storage. Color lightness and yellowness values of meatballs were not affected by the propolis treatment, only difference was observed in redness values. The pH of the meatballs prepared with the propolis extract almost stayed constant during storage, while the pH of the control meatball samples increased. In summary, propolis extract exhibited a strong antimicrobial and antioxidant activity in vivo assays and in a meat product. Accordingly, it should be used in meat product formulations to enhance preservation of meat products.

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Section: Antibacterial Effect Of Propolis Extractmentioning

confidence: 59%

Section: Introductionmentioning

confidence: 99%

Antimicrobial and Antioxidant Activities of Commercialized Turkish Propolis Extract, and Application to Beef Meatballs

Gedikoğlu

2022

Turkish JAF Sci.Tech.

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“…The use of experimental design and, more specifically, response surface methodology is becoming increasingly common in the optimization of polyphenol extraction from natural products, and propolis is one of them [16][17][18].These chemometric tools are used by establishing a mathematical model that evaluates multiple parameters and their interactions using quantitative data, effectively optimizing complex extraction procedures, and thus reducing the number of experimental trials required [18,19].In this same approach, a Box-Behnken design (BBD)was applied to optimize extraction yield, total polyphenols and flavonoids, and antioxidant activity by using DPPH-IC 50 and FRAP-EC 50 tests from Moroccan propolis.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Optimization of Extraction Yield, Phenolic Compounds and Antioxidant Activity of Moroccan Propolis Extracts: Improvement of Ultrasound-Assisted Technique Using Response Surface Methodology

et al. 2022

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Propolis has given rise to refreshing interest in recent years in the field of conventional medicine. Its extraction represents an important process that requires optimal conditions, which strongly affect the yield of extraction, total polyphenols, flavonoid content, and radical scavenging capacity markers. The objective of the present study was to optimize the ultrasound-assisted extraction conditions of Moroccan propolis. The studied responses were the extraction yield, total polyphenols, flavonoid contents (TPC, TFC), and antioxidant activity of the extract evaluated by DPPH-IC50 and FRAP-EC50 assays. The response surface methodology (RSM) and specifically the Box–Behnken design (BBD) were used, taking into account three variables: sonication time (min), solvent/propolis ratio (mL/g), and ethanol concentration (%). After the realization of experiments and data analysis, optimal response values were 15.39%, 192 mg GAE/g of propolis,45.15 mg QEq/g, 29.8 µg/mL, and 128.3 µmol Fe2+/g for extraction yield, TPC, TFC, DPPH-IC50, and FRAP-EC50, respectively. Besides, optimal ultrasound extraction conditions were 15 min for sonication time, 30 mL/g for solvent/propolis ratio, and 40% for ethanol concentration. All obtained experimental values were in good agreement with the predicted values, suggesting that using an experimental design in the ultrasound-assisted extraction process and optimization was prudently chosen.

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“…As metodologias convencionais (sólido-líquido) ainda são muito populares, mesmo com as desvantagens de possuírem baixo ren-dimento, serem demoradas, e modificarem as amostras após extração, devido a degradação ocasionada por oxidação, hidrólise e ionização. Dentre as mais comuns, podem ser citadas maceração, processamento de alta pressão, ultrassom, irradiação gama, fluido supercrítico, Soxhlet e micro-ondas (53,64).…”

Section: Resultsunclassified

“…Bakkaloglu e cols. (2021) estudaram os efeitos do uso de maceração dinâmica e extração por ultrassom, obtendo uma melhor extração de compostos fenólicos e capacidade antioxidante pelo método de ultrassom (64).…”

Section: Resultsunclassified

Fatores De Heterogeneidade Do Potencial Antioxidante Da Própolis Da Abelha Apis Mellifera: Uma Revisão

Cruz¹,

Martins²,

Ferreira³

et al. 2022

Infarma

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As abelhas produzem a própolis a partir de materiais balsâmicos coletados das plantas. Trata-se de um produto natural com diversas funções dentro da colmeia. Atualmente, a ciência já comprovou várias ações biológicas desse material, tal como antioxidante. Porém, ainda há desafios no que concerne a padronização de técnicas de coleta, preparo da amostra, análises, controle de qualidade, dentre outros, dificultando o uso da própolis pela indústria. Essa revisão investigou os possíveis fatores de heterogeneidade do potencial antioxidante da própolis, considerando todo o processo de obtenção, desde origem das colmeias até formas de extração da própolis de abelha Apis mellifera. A busca desta revisão foi realizada nas seguintes bases de dados e ferramentas de busca: SciELO, Google Acadêmico, PubMed, MEDLINE, Catálogo de Dissertações e Teses da CAPES, BVS, CRD, Embase, Science Direct, Scopus e Cochrane Library. Foram incluídas publicações em português, inglês e espanhol (2011 a 2021). Foram obtidos 173 trabalhos que comprovaram importante atividade antioxidante do extrato de própolis de A. melífera. Porém, os resultados numéricos de potencial antioxidante diferiram muito entre si. Os principais fatores de heterogeneidade encontrados nas metodologias foram: local e época de coleta (sazonalidade), raça da abelha, tipo de própolis ou sua fonte botânica, e preparo do extrato (solvente, tempo e metodologia de extração).

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Optimization of ultrasound-assisted extraction of turkish propolis and characterization of phenolic profile, antioxidant and antimicrobial activity

Cited by 16 publications

References 32 publications

Antimicrobial and Antioxidant Activities of Commercialized Turkish Propolis Extract, and Application to Beef Meatballs

Antimicrobial and Antioxidant Activities of Commercialized Turkish Propolis Extract, and Application to Beef Meatballs

Simultaneous Optimization of Extraction Yield, Phenolic Compounds and Antioxidant Activity of Moroccan Propolis Extracts: Improvement of Ultrasound-Assisted Technique Using Response Surface Methodology

Fatores De Heterogeneidade Do Potencial Antioxidante Da Própolis Da Abelha Apis Mellifera: Uma Revisão

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