Optimization of the preparation of a poly(aspartic acid) superabsorbent resin with response surface methodology

Zhao, Ying; Li, Fang; Tan, Tianwei

doi:10.1002/app.23991

Cited by 5 publications

(7 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The method of steepest ascent (descent) is a procedure for moving sequentially along the path of steepest ascent (descent), that is, along the path of the maximum increase (decrease) in the response [18]. For a first-order model in PB design, the contours of the response surface are a series of parallel lines.…”

Section: Methodsmentioning

confidence: 99%

Optimization of Fermentation Conditions and Rheological Properties of Exopolysaccharide Produced by Deep-Sea Bacterium Zunongwangia profunda SM-A87

Liu

Qiao

et al. 2011

PLoS ONE

View full text Add to dashboard Cite

Zunongwangia profunda SM-A87 isolated from deep-sea sediment can secrete large quantity of exopolysaccharide (EPS). Response surface methodology was applied to optimize the culture conditions for EPS production. Single-factor experiment showed that lactose was the best carbon source. Based on the Plackett–Burman design, lactose, peptone and temperature were selected as significant variables, which were further optimized by the steepest ascent (descent) method and central composite design. The optimal culture conditions for EPS production and broth viscosity were determined as 32.21 g/L lactose, 8.87 g/L peptone and an incubation temperature of 9.8°C. Under these conditions, the maximum EPS yield and broth viscosity were 8.90 g/L and 6551 mPa•s, respectively, which is the first report of such high yield of EPS from a marine bacterium. The aqueous solution of the EPS displayed high viscosity, interesting shearing thinning property and great tolerance to high temperature, a wide range of pH, and high salinity.

show abstract

Section: Methodsmentioning

confidence: 99%

Optimization of Fermentation Conditions and Rheological Properties of Exopolysaccharide Produced by Deep-Sea Bacterium Zunongwangia profunda SM-A87

Liu

Qiao

et al. 2011

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…It was then [72,73] and (b) R ¼ hexamethyene chain. [74][75][76][77][78][79] cured with PEG-diepoxide (30-50 mol%) at various temperatures (60-1008C) and time (1-20 hr) to yield polyaspartate SAP hydrogels. Lower curing temperature and time, as well as the lower MW PEG-diepoxide, resulted in the hydrogels with higher swelling capacities (400-1100 g/g in distilled water, 40-70 g/g in 0.9% NaCl).…”

Section: Homo Poly(amino Acid) Super-swelling Hydrogelsmentioning

confidence: 99%

“…[71][72][73] Tan et al focused on the preparation and characterization of PASP-based super-swelling hydrogels via a diamine-crosslinking reaction. [74][75][76][77][78][79] Their synthetic approach is shown in Fig. 10(b).…”

Section: Homo Poly(amino Acid) Super-swelling Hydrogelsmentioning

confidence: 99%

“…[74] Response surface methodology (RSM), a mathematical and statistical technique widely used to reflect the effects of several variables and to optimize different biotechnological processes, was employed for optimizing the preparation of the PASP superswelling hydrogel. [75] The technique included the Plackett-Burman (P-B) design, the path of steepest accent, and central composite design (CCD), predicted accurately the maximum point of the swelling ratio. Under the optimal conditions (i.e.…”

Section: Homo Poly(amino Acid) Super-swelling Hydrogelsmentioning

confidence: 99%

See 1 more Smart Citation

Protein‐ and homo poly(amino acid)‐based hydrogels with super‐swelling properties

Zohuriaan‐Mehr

Pourjavadi

Satha

et al. 2009

Polymers for Advanced Techs

115

View full text Add to dashboard Cite

The use of super-swelling polymers is steadily increasing and the applications in industry are continuing to grow. With the authorization of the superabsorbents in food packaging by the Food and Drug Administration recently, demand may soon take off in the market. However, the increase in prices of petroleum products in recent years may be a drawback for these acrylic-based materials. Thus, there is now a need to develop natural-based super-swelling hydrogels which are more economical and environment friendly. In addition, the super-swelling gels are promising novel functions in the biomedical and pharmaceutical applications. This review is aimed to highlight research and trends in protein-and homo poly(amino acid)-based super-swelling hydrogels. Thus, the proteinaceous hydrogels, including chemically modified soy-, fish-and collagen-based proteins, are discussed. The protein-polysaccharide, protein-synthetics, and the inorganic composites are also investigated as hybrid materials. Finally, the super-swelling hydrogels based on homo polypeptides, i.e. poly(aspartic acid), poly(glutamic acid), and poly(e-L-lysine) are reviewed.

show abstract

“…Owing to the fact that the initial estimates of experiment conditions are usually far from the actual optimum, a method is needed to move rapidly to the general proximity of the optimum condition. The method of steepest ascent (descent) is a procedure for moving sequentially along the path of steepest ascent (descent), that is, along the path of the maximum increase (decrease) in the response [10].…”

Section: Methodsmentioning

confidence: 99%

Factorial design analysis and optimisation of chitosan‐based nanogels as controlled release system for gentamicin

Zabihian

Salouti

Hamidi

2017

IET nanobiotechnol.

View full text Add to dashboard Cite

The aim of this study was preparation and optimisation of a controlled-release delivery system to decrease the dosedependent side effects of gentamicin. Hydrogel nanoparticles composed of a polycationic polymer (chitosan) and an inorganic polyanion (sodium tripolyphosphate) were fabricated in the presence of gentamicin. An experimental design was drawn upon to determine the optimum condition of nanoparticle preparation. Various features of the nanoparticles including drug loading parameters, particle size distribution, zeta potential and in vitro drug release profile were evaluated. Ultimately, the antimicrobial activity of the gentamicin-loaded nanoparticles was analysed by determination of the minimum inhibitory concentration (MIC) and the potency test. As a result, the nanocarriers with an average size of about 250 nm (unloaded) and 493 nm (gentamicinloaded) were obtained with unimodal distribution and a notable polydispersity index (≤0.3). The drug loading efficiency was between 28 and 32%. The gradual and sustained releases (∼90%) of gentamicin were achieved in 24 h. The MIC and potency test showed no significant decrease in the antibacterial activity of gentamicin-loaded nanoparticles. The outcomes demonstrated that the optimised chitosan nanogels prepared in this study can be considered as a suitable carrier for a controlled release system.

show abstract

Optimization of the preparation of a poly(aspartic acid) superabsorbent resin with response surface methodology

Cited by 5 publications

References 65 publications

Optimization of Fermentation Conditions and Rheological Properties of Exopolysaccharide Produced by Deep-Sea Bacterium Zunongwangia profunda SM-A87

Optimization of Fermentation Conditions and Rheological Properties of Exopolysaccharide Produced by Deep-Sea Bacterium Zunongwangia profunda SM-A87

Protein‐ and homo poly(amino acid)‐based hydrogels with super‐swelling properties

Factorial design analysis and optimisation of chitosan‐based nanogels as controlled release system for gentamicin

Contact Info

Product

Resources

About