Optimization of spin-valve parameters for magnetic bead trapping and manipulation

Altman, Wendy R.; Moreland, John; Russek, Stephen E.; Bright, Victor M.

doi:10.1016/j.jmmm.2010.05.043

Cited by 7 publications

(3 citation statements)

References 16 publications

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“…The solution has been to array GMR sensors in conjunction with microfluidic channels, to thereby increase the sensing area in contact with suspensions of magnetic beads by restricting the suspension fluid to a region near the detection volume of the sensors. Work by Altman et al [4], based on earlier work by Mirowski et al [5], and work by Millen et al [6], showed that magnetic beads in diameter can be detected in a constant microfluidic flow environment using GMR sensors. For MNPs however, microfluidic channels alone do not bring particles close enough to the sensors for adequate detection.…”

Section: Introductionmentioning

confidence: 99%

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Microfluidic Platform for Magnetic Nanoparticle Trapping and Detection

2013

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We evaluate giant magnetoresistance sensors to trap and count small concentrations of magnetic nanoparticles (MNPs) within microfluidic flow. The device presented takes the novel approach of capturing and detecting MNPs utilizing the strong fringe-fields present on the periphery of the patterned sensor. The presence of MNPs manifests as a field shift in the magnetoresistance curve. Tests of the device have shown a noticeable response to MNPs with 30 nm nominal core diameters at concentrations as low as at a flow rate of 5 . Such a device would be beneficial for bio-medical applications, including immunoassays, and for monitoring filtration processes, where large sample fluid volumes and low MNP concentration sensitivities are required.

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Section: Introductionmentioning

confidence: 99%

“…In Altman's work, captured beads are detected as an increase in switching field [4]. Because the beads are on the same order of size as the SV, they cause a noticeable change to the switching dynamics of the SV.…”

Section: Introductionmentioning

confidence: 99%

Microfluidic Platform for Magnetic Nanoparticle Trapping and Detection

2013

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“…For the optimization of the valve, the literatures [1][2][3] have done a lot of research. But the optimization is not isolated.…”

Section: Introductionmentioning

confidence: 99%

Multidisciplinary Design Optimization of a High-Flow Control Valve

Cao

Yong

2013

AMM

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According to the real structure and work condition of a high-flow gas pressure control valve used in recycling generating electricity project, a multidisciplinary design optimization (MDO) model is set up. Taking the structure and flow field analysis results as designing criterion, the MDO framework is put forward, which realizing the integration of multidisciplinary and two physical fields of control valve. To ensure that the gas transmission capacity which is the design prerequisite, the optimization takes reducing noise of control valve as system goal, while the valve wall thickness and flow velocity are decreased. And the Reynolds number, stress intensity and body total weight are also meet requirements. From the standpoint of fluid and structure, to realize MDO is of great practical significance for advancing research level of high-flow control valves.

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Versatile, high sensitivity, and automatized angular dependent vectorial Kerr magnetometer for the analysis of nanostructured materials

Teixeira

Lusche

Ventura

et al. 2011

Review of Scientific Instruments

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Magneto-optical Kerr effect (MOKE) magnetometry is an indispensable, reliable, and one of the most widely used techniques for the characterization of nanostructured magnetic materials. Information, such as the magnitude of coercive fields or anisotropy strengths, can be readily obtained from MOKE measurements. We present a description of our state-of-the-art vectorial MOKE magnetometer, being an extremely versatile, accurate, and sensitivity unit with a low cost and comparatively simple setup. The unit includes focusing lenses and an automatized stepper motor stage for angular dependent measurements. The performance of the magnetometer is demonstrated by hysteresis loops of Co thin films displaying uniaxial anisotropy induced on growth, MnIr/CoFe structures exhibiting the so called exchange bias effect, spin valves, and microfabricated flux guides produced by optical lithography.

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Optimization of spin-valve parameters for magnetic bead trapping and manipulation

Cited by 7 publications

References 16 publications

Microfluidic Platform for Magnetic Nanoparticle Trapping and Detection

Microfluidic Platform for Magnetic Nanoparticle Trapping and Detection

Multidisciplinary Design Optimization of a High-Flow Control Valve

Versatile, high sensitivity, and automatized angular dependent vectorial Kerr magnetometer for the analysis of nanostructured materials

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