Optimization of reactive simulated moving bed systems with modulation of feed concentration for production of glycol ether ester

Agrawal, Gaurav; Oh, Jae Min; Sreedhar, Balamurali; Tie, Shan; Donaldson, Megan E.; Frank, Timothy C.; Schultz, Alfred K.; Bommarius, Andreas S.; Kawajiri, Yoshiaki

doi:10.1016/j.chroma.2014.07.080

Cited by 19 publications

(15 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The temperature of stage 9-stage 13 was less than 80 ∘ C, only the temperature of stage 14 showed a little increase. Figure 16 exhibits the mole fraction of C 6…”

Section: Extraction Ratiomentioning

confidence: 99%

“…studied the application of reactive chromatography for MPA production with Amberlyst‐15 resin as catalytic adsorbent. Agrawal et al . presented a moving bed reactor model that maximized the production rate of MPA with Amberlyst‐15 resin as catalyst.…”

Section: Introductionmentioning

confidence: 99%

“…4 Oh et al 5 studied the application of reactive chromatography for MPA production with Amberlyst-15 resin as catalytic adsorbent. Agrawal et al 6 presented a moving bed reactor model that maximized the production rate of MPA with Amberlyst-15 resin as catalyst. This type of resin, composed of divinylbenzene, styrene and a sulfonic acid group which is the active site of the catalyst, 7 showed excellent performances in selectivity and reusability.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A combination of low‐temperature reactive and extractive distillation for methoxy‐2‐propyl acetate synthesis and separation process: simulations and experiments

Wang

Cai

et al. 2019

J of Chemical Tech & Biotech

View full text Add to dashboard Cite

BACKGROUND Esterification of methoxy propanol (MP) and acetic acid (HAC) to methoxy‐2‐propyl acetate (MPA) is a typical reversible reaction. The yield of MPA is low owing to the limitation of chemical equilibrium. In the present study, with the goal of increasing the reaction conversion and preventing the NKC‐9 cation exchange resin catalyst from deactivation at high temperature, a process combining low‐temperature reactive and extractive distillation with cyclohexane (C6H12) as entrainer was investigated by process simulations and experiment methods. RESULTS The intrinsic kinetic parameters were obtained by catalyst activity evaluation in a batch reactor. Binary interaction parameters of thermodynamic models were determined by the measurement and fitting of vapor–liquid equilibrium data. The effects of different operating parameters on the reaction conversion and column performance were examined in detail, and a production process of MPA with an annual output of 56 000 tons was suggested. The results showed that the purity of MPA reached nearly 100% after further purification following reactive distillation, and the reaction temperature was controlled in the range 75–80 °C, which allowed long‐term operation thermal stability of the catalyst. CONCLUSION The developed low‐temperature reactive distillation method ensured a long life of the ion exchange resin catalyst, which should provide insights into further advances of MPA industrial production. © 2019 Society of Chemical Industry

show abstract

“…The temperature of stage 9-stage 13 was less than 80 ∘ C, only the temperature of stage 14 showed a little increase. Figure 16 exhibits the mole fraction of C 6…”

Section: Extraction Ratiomentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A combination of low‐temperature reactive and extractive distillation for methoxy‐2‐propyl acetate synthesis and separation process: simulations and experiments

Wang

Cai

et al. 2019

J of Chemical Tech & Biotech

View full text Add to dashboard Cite

show abstract

“…In contrast, the feed concentration can be varied during each switching period using the ModiCon, i.e., periodically modified feed concentration strategy , . The concept of ModiCon was applied to a simulated moving bed reactor (SMBR) to produce propylene glycol methyl ether acetate . The concentrated feed increased the net reaction rate locally, thus enhancing the purity, recovery, and productivity.…”

Section: Operating Strategies To Extend the Potential Of Conventionalmentioning

confidence: 99%

Advanced Operating Strategies to Extend the Applications of Simulated Moving Bed Chromatography

et al. 2017

View full text Add to dashboard Cite

Chromatographic separation with solid stationary and fluid mobile phases is widely used to isolate and purify compounds. One of the most productive improvements in preparative chromatography is the simulated moving bed (SMB) process, which enables continuous feed supply and product removal by periodic operation of a multicolumn to simulate a countercurrent flow between the phases. The SMB process produces high‐purity compounds, even with low selectivity, and offers higher productivity and lower eluent consumption than batch chromatography. Recently, intensive efforts have been made to expand the range of applications through the design, modeling, and optimization of the SMB process to produce advanced operating strategies, which are described and evaluated in this review.

show abstract

“…High-purity products can be produced through coupling of chemical reactions and chromatographic separations. 1 The type of reaction, together with the desired order of elution of the components, largely influences a reactive chromatographic process. In the case in which reactant elutes in the middle of the products, a separation with high purity of products can be achieved.…”

Section: Introductionmentioning

confidence: 99%

Analysis of two‐dimensional models for liquid chromatographic reactors of cylindrical geometry

Uche

Qamar

Seidel‐Morgenstern

2019

Int J of Chemical Kinetics

View full text Add to dashboard Cite

This work presents the analytical solutions of two-dimensional isothermal reactive general rate models for liquid chromatographic reactors of cylindrical geometry. Both irreversible and reversible reactions are considered. The model equations form a linear system of convection-diffusion-reaction partial differential equations coupled with algebraic equations for isotherms. Analytical solutions are derived by integrated implementation of finite Hankel transform, Laplace transform, eigen-decomposition technique, and conventional ordinary differential equations solution technique. To verify the analytical results, a high-resolution finite volume scheme is also applied to numerically approximate the model equations. The current results can be very useful to optimize and upgrade the liquid chromatographic reactors. K E Y W O R D S analytical solutions, general rate model, liquid chromatography, numerical solutions, reactions and separations Int J Chem Kinet. 2019;51:563-578.

show abstract

Optimization of reactive simulated moving bed systems with modulation of feed concentration for production of glycol ether ester

Cited by 19 publications

References 50 publications

A combination of low‐temperature reactive and extractive distillation for methoxy‐2‐propyl acetate synthesis and separation process: simulations and experiments

A combination of low‐temperature reactive and extractive distillation for methoxy‐2‐propyl acetate synthesis and separation process: simulations and experiments

Advanced Operating Strategies to Extend the Applications of Simulated Moving Bed Chromatography

Analysis of two‐dimensional models for liquid chromatographic reactors of cylindrical geometry

Contact Info

Product

Resources

About