“…Furthermore, the data observed in many peer-reviewed efforts use simple mixtures or even pure samples of target organisms, which do not reflect the real-life situations where samples contain hundreds of organisms and diverse biological materials. The MS techniques that have been investigated include pyrolysis MS (Tripathi et al, 2001 ; Wilkes et al, 2006 ), pyrolysis-derivatization MS/MS (Griest et al, 2001 ), derivatization gas chromatography GC-MS (Jeong et al, 2014 ), aerosol laser ablation (LA) MS (Fergenson et al, 2004 ), and aerosol matrix assisted laser desorption/ionization (MALDI) MS (Jung et al, 2014 ). The high cost, generally large footprint, and power requirements (mostly because of vacuum pumps) are factors that have limited the application of MS in autonomous detection devices.…”