Optimization of microwave-assisted extraction of hydrophilic and lipophilic antioxidants from a surplus tomato crop by response surface methodology

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A B S T R A C TGomphrena globosa L. is a source of betacyanins, molecules with high colorant power. In order to replace conventional extraction techniques, microwave (MAE) and ultrasound assisted extraction (UAE) processes were optimized by the response surface methodology (RSM) to maximize the recovery of betacyanins from G. globosa. A five-level full factorial design of 24 combinations and 4 replicates was implemented for MAE and UAE. The optimum processing conditions for MAE (t = 8 min; T = 60°C; Et = 0%; and S/L = 5 g/L) conducted to an extraction yield of 39.6 ± 1.8 mg/g dry weight, while for UAE (t = 22 min; P = 500%; Et = 0%; and S/ L = 5 g/L) a value of 46.9 ± 4.8 mg/g was achieved, validating the UAE more suitable to obtain the target compounds. This technique can provide extracts rich in betacyanins and with high potential to be used as natural colorants.

Section: Optimal Extraction Conditions For Maximizing the Responses Cmentioning

confidence: 99%

“…For response optimization, a maximization process was applied using a simple method tool to solve non-linear problems (Heleno et al, 2016;Pinela et al, 2016a). Constraints were imposed to the variable coded values to avoid unnatural conditions (i.e., times lower than 0).…”

Section: Procedures To Optimize the Variables To A Maximum Responsementioning

confidence: 99%

Modern extraction techniques optimized to extract betacyanins from Gomphrena globosa L.

Roriz

Barros

Prieto

et al. 2017

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“…A simplex method was used to maximize the model process by solving non-linear problems to optimize the response criteria selected (P1, P2, P3 and total HPLC) (Heleno et al, 2016;Pinela et al, 2016). To avoid unnatural conditions of the variables, certain limitations were imposed (i.e., times lower than 0).…”

Section: Procedures To Optimize the Variables To A Maximum Responsementioning

confidence: 99%

Enhanced extraction of phenolic compounds using choline chloride based deep eutectic solvents from Juglans regia L.

Vieira

Prieto

Barros

et al. 2018

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113

A B S T R A C TThe extraction of phenolic compounds from walnut leaves (Juglans regia L.) was optimized using heat-assisted extraction and deep eutectic solvents based on choline chloride and carboxylic acids. A preliminary solvent screening was performed using a selected group of carboxylic acids as hydrogen bond donors, showing that the highest extraction yield of phenolic compounds was obtained using choline chloride mixtures with butyric or phenylpropionic acid at a mole ratio 1:2, with 20% of water (w/w). The extraction conditions (time, temperature and water proportion) were then optimized by an experimental design, assisted by response surface methodology. To evaluate the response, the three most abundant compounds identified by HPLC (neochlorogenic acid, quercetin 3-O-glucoside and quercetin O-pentoside) were quantified. Additionally, the solid/liquid ratio effect at the optimal conditions, in dose-response format, was studied in view of its upscale, not showing any significant decrease until 140 g/L. The results here presented provide valuable information towards the design of a process in a pre-industrial form for the extraction of phenolic compounds from J. regia leaves using deep eutectic solvents.

“…Proper utilization of this by-product could reduce waste disposal problems and serve as a potential new source of bioactive compounds and pigments. According to several authors (Belwal et al, 2016;GarciaCastello et al, 2015;Pinela et al, 2016;Rao, 2010), one of the best ways to use this kind of by-products could be the application of an appropriate green solid-liquid extraction technology in order to obtain bioactive compounds with different properties and health benefits. Several studies marked fruits and fruits by-products as a rich source of natural molecules such as polyphenols (i.e.…”

Section: Introductionmentioning

confidence: 99%

By-product recovery of Opuntia spp. peels: Betalainic and phenolic profiles and bioactive properties

Melgar

Días

Ćirić

et al. 2017

A B S T R A C TOpuntia spp. are a tropical and subtropical plant that provides both edible green steams and fruits; however, the processing of this fruits results in the accumulation of enormous amount of by-products that can be a source of bioactive and pigmented compounds. Herein, three cactus pear from the species Opuntia ficus-indica var. sanguigna (OS) and gialla (OG) and Opuntia engelmannii (OE) were fully characterized regarding their phenolic and betalain composition and correlated with their antioxidant and antimicrobial activities. The hydroethanolic extracts of OE gave the highest amount of phenolic compounds isorhamentin-O-(deoxyhexosyl-hexoside) and betacianins (betanin); however, no betaxanthins were identified in this sample. This sample also revealed the lowest EC 50 values in all the antioxidant activity assays. Regarding antimicrobial activity, the hydroethanolic extracts of all species revealed to be more active than ampicillin. The pivotal objective of this work was to focus on exploring by-product biocompounds and possible outputs, thus, we could suggest the use of these natural colorants with intrinsic antioxidant and antimicrobial activity, which would grant industries to produce cleaner label products with functional benefits.