Optimization of extraction condition for major iridoid components in fruit of corni (Cornus officinalis) by UPLC-PDA using response surface methodology

Lee, A Yeong; Kim, Hyo Sun; Jo, Ji Eun; Kang, Byoung Kab; Moon, Byeong Cheol; Chun, Jin Mi; Ji, Yunui; Kim, Ho Kyoung

doi:10.1007/s10068-012-0133-y

Cited by 10 publications

(5 citation statements)

References 25 publications

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“…In order to estimate the optimization of the UAE process of Sideritis raeseri , we use the RSM as a compilation of mathematical and statistical analyses established on the fit of polynomial equations to the experimental data [ 14 ]; this describes well the behaviour of the dataset, aiming to make statistical previsions; since it reduces time, space, and raw material usage, it is more favourable than the traditionally used single parameter optimization [ 15 ]. Such a model of the optimization of the UAE process of Sideritis species is lacking.…”

Section: Resultsmentioning

confidence: 99%

Optimization of Ultrasound-Assisted Extraction of Phenolics from Sideritis raeseri Using Response Surface Methodology

et al. 2021

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In this study we define the optimal conditions for ultrasound-assisted extraction of bioactive polyphenols from S. raeseri aerial parts using response surface methodology. The influence of ethanol concentration (10–90%), extraction temperature (20–80 °C), extraction time (10–60 min), and solid-to-solvent ratio (1:10–1:50) on total phenolic content as well as on content of individual flavonoids, and hypolaetin and isoscutellarein derivatives was studied. For the experimental design, a central composite design was chosen. In the obtained extracts, the following ranges of targeted compounds were detected: total phenol from 19.32 to 47.23 mg GAE/g dw, HYP from 1.05 to 11.46 mg/g dw, ISC 1 from 0.68 to 10.68 mg/g dw, and ISC 2 from 0.74 to 15.56 mg/g dw. The optimal extraction conditions were set as: ethanol concentration of 65%, extraction time of 50 min, extraction temperature of 63 °C, and solid-to-solvent ratio of 1:40. Contents of TP, HYP, ISC 1, and ISC 2 in optimal extracts were 47.11 mg GAE/g dw, 11.73 mg/g dw, 9.54 mg/g dw, and 15.40 mg/g dw, respectively. Experimentally set values were in good agreement with those predicted by the response surface methodology model, indicating suitability of the used model, as well as the success of response surface methodology in optimizing the conditions of the extraction.

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Section: Resultsmentioning

confidence: 99%

Optimization of Ultrasound-Assisted Extraction of Phenolics from Sideritis raeseri Using Response Surface Methodology

et al. 2021

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“…It well explains the nature of data set aiming to make arithmetical prediction/forecasting. Compared to conventionally used single‐factor optimization, RSM is more favorable due to the fact that it saves time, sample usage, and space (Lee et al, ).…”

Section: Resultsmentioning

confidence: 99%

Effect of sonication pretreatment parameters and their optimization on the antioxidant activity ofHermitia illucenslarvae meal protein hydrolysates

Mintah

Dabbour

et al. 2019

J Food Process Preserv

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The study investigated the effect of sonication conditions on antioxidant activity of Hermetia illucens larvae meal protein hydrolysates. Three-factor three-level: pH (7-9), time (10-30 min), and temperature (25-55°C) were optimized. Box-Behnken's design was applied to optimize sonication treatment. Ferrous ion chelating activity (ICA), DPPH-radical scavenging activity (DPPHRSA), Hydroxyl radical scavenging activity (HRSA), and cupric ion chelating activity (CCA) were considered as responses.Findings demonstrated that sonication preceding enzymolysis significantly impacted on ICA, DPPHRSA, HRSA, and CCA. ANOVA showed the determination coefficient (R 2 ) were 0.98 (ICA), 0.99 (DPPHRSA), 0.98 (HRSA), and 0.88 (CCA); demonstrating that the models were reasonably fit with experimental results. Optimum sonication conditions were pH (9), time (29.84 min), and temperature (54.93°C). For these conditions, the experimental data obtained [ICA (37.84%), DPPHRSA (43.19%), HRSA (71.01%), and CCA (68.93%)] were consistent with predicted values, higher than control, and supported by protein subunits, fluorescence spectra and microstructure. Practical applicationsWith a rich nutrient profile, edible insects are potential ingredient for food applications. Hermetia illucens is one of the most encouraging edible insect species for incorporation in food products as it has several benefits to the environment, coupled with the already available knowhow for their rearing. With the prediction that in the next few decades insects will be reliable source of protein for humans and livestock, it is logical that the antioxidants activity of insect larvae meal proteins are investigated for new product development. Ultrasound is reported to enhance enzyme action in the preparation of bioactive hydrolysates/peptides. The present study showed that the use of ultrasonication pretreatment in the enzymatic hydrolysis of HILMP to generate hydrolysates with antioxidant constituents was efficient (likened to conventional approach). The study outcome could help the food and/or pharmaceutical industry to advance new bioactive products/ functional foods from HILMP hydrolysates. (Jiangsu, China), and were microwave dried prior to milling and defatting. How to cite this article: Mintah BK, He R, Dabbour M, Golly MK, Agyekum AA, Ma H. Effect of sonication pretreatment parameters and their optimization on the antioxidant activity of Hermitia illucens larvae meal protein hydrolysates. J Food

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“…As the optimal condition (Lee et al ., ), two grams of Corni fructus powder was extracted with 100 mL of 64% (v/v) aqueous ethanol for 38 min at 78 °C. The remaining steps were the same with the UCGE method.…”

Section: Methodsmentioning

confidence: 99%

“…Extraction is the most extensively used methodology in the process of natural product purification. Conventional solvent extraction method has been reported for the extraction of iridoid glycosides from Corni fructus (Lee et al, 2012) using volatile and hazardous organic solvent. Ultrasound-assisted extraction is a novel and improved strategy for edible fruits extraction (Zou et al, 2010;Xu & Pan, 2013), which not only increases extraction efficiency but also minimises the consumption of unpleasant petroleum-based solvents (Rostagno et al, 2003;Zuo et al, 2004;Wang et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Optimisation of green ultrasonic cell grinder extraction of iridoid glycosides from Corni fructus by response surface methodology

Xie

Chen

et al. 2013

Int J of Food Sci Tech

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Summary Ultrasonic cell grinder extraction (UCGE), employing water as solvent, was proposed as a sustainable and efficient method for the extraction of two iridoid glycosides (morroniside and loganin) from Corni fructus. Extraction yields were determined by four variables: ratio of solution to solid, extraction power, extraction buffer time and extraction time. Data analysis by response surface methodology showed that best yields, 2.176% ± 0.006% (predicted value of 2.195%) for morroniside and 0.839% ± 0.004% (predicted value of 0.852%) for loganin, were obtained when the values of these four variables were set at 45:1 mL g−1, 1600 w, 2.3 s and 40 min, respectively. The yields of morroniside and loganin using UCGE method were 0.198–0.279% and 0.167–0.181% higher than that of traditional heat reflux extraction method, respectively. Thus, the UCGE method is more productive, economic and environmentally friendly and has great potential to be used widely in natural product chemistry.

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Optimization of extraction condition for major iridoid components in fruit of corni (Cornus officinalis) by UPLC-PDA using response surface methodology

Cited by 10 publications

References 25 publications

Optimization of Ultrasound-Assisted Extraction of Phenolics from Sideritis raeseri Using Response Surface Methodology

Optimization of Ultrasound-Assisted Extraction of Phenolics from Sideritis raeseri Using Response Surface Methodology

Effect of sonication pretreatment parameters and their optimization on the antioxidant activity ofHermitia illucenslarvae meal protein hydrolysates

Optimisation of green ultrasonic cell grinder extraction of iridoid glycosides from Corni fructus by response surface methodology

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