Optimization of 3D-Visualization of Micro-Anatomical Structures of the Human Inner Ear in Osmium Tetroxide Contrast Enhanced Micro-CT Scans

Zhou

et al. 2020

Rev. Assoc. Med. Bras.

SUMMARY OBJECTIVE This study aims to investigate the application value of magnetic resonance (MR) hydrography of the inner ear in cochlear implantation. METHODS 146 patients were enrolled. MR hydrography and spiral CT examinations for the intracranial auditory canal were performed before surgery, and all imaging results were statistically analyzed in order to explore the application value of MR hydrography of the inner ear in cochlear implantation. RESULTS 146 patients (292 ears) were examined. Among these patients, 13 were diagnosed with abnormal vestibular aqueducts (20 ears) by MR hydrography, while five were diagnosed with this disease by CT; 15 patients were diagnosed with inner ear malformation (19 ears) by MR hydrography, while 11 were diagnosed by CT (four were misdiagnosed); five patients were diagnosed with internal acoustic canal stenosis (eight ears) by MR hydrography, while two were diagnosed by CT (three were misdiagnosed); and four patients were diagnosed with cochlear fibrosis (five ears) by MR hydrography, while four were diagnosed by CT (four ears). The correct rate of diagnosis was 77.40% (113/146) based on CT, while the rate was 93.84% (137/146) based on MR hydrography. CONCLUSIONS MR hydrography imaging technique can be applied to the preoperative evaluation of cochlear implantation, providing accurate and reliable anatomic information on the inner membranous labyrinth and nerves in the internal acoustic canal and an accurate basis for the diagnosis of cochlear fibrosis and nerve development. This has a guiding significance for the selection of treatment schemes.

Section: Application Value Of Magnetic Resonance Hydrography Of the Imentioning

confidence: 99%

Application value of magnetic resonance hydrography of the inner ear in cochlear implantation

Zhou

et al. 2020

Rev. Assoc. Med. Bras.

J of Comparative Neurology

“…Various studies have looked at shrinkage resulting simply from tissue fixation. For example, studies comparing fixed versus unfixed ocular tissue (Tran et al, 2017) or mixed tissue samples (Ferguson, Bryant, & Ito, 1999) found formalin or paraformaldehyde fixation-induced shrinkage to be less than 2%. Although we made no attempt to quantify shrinkage in the present study, the literature would suggest that we experienced less than 5% shrinkage.…”

Section: Methods Specific To the Cochleamentioning

confidence: 99%

Light sheet microscopy of the gerbil cochlea

Hutson

Pulver

Ariel

et al. 2020

“…For example, Guyader et al 6 found CT and cone beam computed tomography (CBCT) were the reliable imaging modalities for providing 3D reconstructions of the temporal bone. Boogert et al 7 revealed that the combination of OsO4, micro-CT, and the proposed image processing algorithm provides an accurate and detailed visualization of the 3D micro-anatomy of the human inner ear. More importantly, the accuracy and reliability of linear measurements using 3D computed tomographic imaging software for Le Fort I osteotomy had been investigated 8 .…”

Section: Introductionmentioning

confidence: 99%

Accuracy and Reliability of Computer‐aided Anatomical Measurements for Vertebral Body and Disc Based on Computed Tomography Scans

Yao

Dong

Sun

et al. 2020

Orthopaedic Surgery

Objective To assess whether the computed tomography (CT)‐based method of three‐dimensional (3D) analysis (Mimics) was accurate and reliable for spine surgical anatomical measurements. Methods A total of 40 lumbar segments and 32 inter‐vertebral discs from eigth adult male cadavers without fractures or deformities fixed with the classical formaldehyde method were included in this research on 5 June 2017. CT scans including seven dimensions: anterior height of the vertebral body (VBHa), middle height of the vertebral body (VBHm), posterior height of the vertebral body (VBHp), width of the upper endplate (EPWu), depth of the upper endplate (EPDu), anterior height of the inter‐vertebral disc in the median sagittal plane (IDHa), and posterior height of the inter‐vertebral disc in the median sagittal plane (IDHp). They were performed based on uniform conditions (slice thickness: 0.625 mm) using a CT scanner on 8 June 2017. Afterwards, the surgical anatomical measurements were conducted with a Vernier caliper on 12 June 2017. The computer‐aided anatomical measurements were conducted by three investigators using Mimics 16.0 to perform 3D reconstructions of CT bone on 16 June 2017. Finally, the length and angle were measured with associated measurement tools, yielding a verified accuracy of 0.01 mm and 0.01°, respectively. Each measurement was repeated three times, and all anatomical data was analyzed using the statistical software and P‐value < 0.05 was considered statistically significant. Results The results showed no statistically significant difference was observed between the surgical anatomical and computer‐aided anatomical measurements (P > 0.05) for lumbar vertebra measurements, and the absolute difference between surgical and computer‐aided data were all less than 1.0 mm (for the VBHa, VBHm, VBHp, EPWu, and EPDu were 0.12, 0.03, 0.03, 0.31, and 0.03 mm, respectively). Moreover, although the absolute differences of discs was larger than those of lumbar vertebras, no significant differences were detected between the computer‐aided and surgical anatomical measurements for the IDHa, as well as IDHp in the vast majority of measurements (P = 0.543, 0.079 or 0.052 for IDHa, and P = 0.212, 0.133 or 0.042 for IDHp). In addition, excellent reliability correlation was observed between the measurements of each investigator, and the reliability coefficients in the intra‐groups were all greater than 0.9 except for IDHp (reliability coefficient = 0.892). Additionally, the reliability coefficients were greater than 0.9 for the all between‐group correlations, and a significant correlation was also observed. Furthermore, no statistically significant difference for three anatomical values was found in the computer‐assisted measurements of the lumbar bone structure (P > 0.05). Similarly, we did not observe a statistical difference in the anatomical data of the lumbar discs from the three measures (P > 0.05). Conclusions Computer‐aided anatomical measurement for spine based on CT scans presents the high accuracy and reliability for ...