Optimising inflammatory bowel disease surveillance and dysplasia management—Where do we stand?

Bakir, Ibrahim Al; Kabir, Misha; Yalchin, Mehmet; Hart, Ailsa

doi:10.1002/ueg2.12330

Cited by 7 publications

(4 citation statements)

References 73 publications

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“…The development of structured training programs and limiting IBD surveillance colonoscopies to experienced endoscopists are 2 possible ways to overcome this issue. 18 Endoscopists should also be more aggressive in the management of any visible lesions. En bloc resection in clearly demarcated lesions, without signs of deep submucosal invasion or fibrosis, should be routinely performed, over targeted biopsies, which may compromise future resection attempts.…”

Section: Discussionmentioning

confidence: 99%

Concordance of Dye-Spraying Chromoendoscopy and Virtual Chromoendoscopy for Colonic Dysplasia Detection in Longstanding Inflammatory Bowel Disease

Correia,

Ponte,

Proenca

et al. 2023

Turkish Journal of Gastroenterology

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Background/Aims: In the past, dye-spraying chromoendoscopy was the technique of choice for colonic surveillance in patients with long-standing extensive inflammatory bowel disease. Recent evidence suggests that virtual chromoendoscopy is an equally acceptable technique. Materials and Methods: Eleven gastroenterologists were given a survey with 20 pairs of pictures from inflammatory bowel disease surveillance colonoscopies (10 with nondysplastic lesions, 5 with dysplastic lesions, and 5 with no lesions). Each pair contained the same image captured during colonoscopy using indigo carmine and narrow-band imaging. For each picture, the gastroenterologist assessed the presence/absence of lesion and, when a lesion was identified, assessed the presence/absence of dysplasia and delineated its margins. To compare lesion and dysplasia detection between techniques, sensitivity, specificity, and interobserver agreement were calculated. The chi-square test was used to assess the accuracy of margins delineation. Results: When assessing lesion and dysplasia detection, similar sensitivity and specificity values were obtained for both techniques. Interobserver agreement analysis revealed that dye-spraying chromoendoscopy and virtual chromoendoscopy had a moderate agreement in lesion detection but, for dysplasia detection, dye-spraying chromoendoscopy had a slight agreement [ K = 0.11 (0.03-0.18), P < .01] and virtual chromoendoscopy a fair agreement [ K = 0.30 (0.22-0.37), P < .01]. Margin delineation was similar between techniques. Conclusion: Sensitivity and specificity for lesion and dysplasia detection, as well as the accuracy of margins delineation, were similar between dye-spraying chromoendoscopy and virtual chromoendoscopy. Interobserver agreement for dysplasia detection was suboptimal in both techniques; however, it was superior when using virtual chromoendoscopy. These findings suggest that virtual chromoendoscopy constitutes a valid alternative for dysplasia screening in inflammatory bowel disease.

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Section: Discussionmentioning

confidence: 99%

Concordance of Dye-Spraying Chromoendoscopy and Virtual Chromoendoscopy for Colonic Dysplasia Detection in Longstanding Inflammatory Bowel Disease

Correia,

Ponte,

Proenca

et al. 2023

Turkish Journal of Gastroenterology

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“…To maximize the efficacy of endoscopic surveillance, optimized mucosal visualization and improved operator performance are crucial [ 50 ]. Recently, several new endoscopic techniques have emerged to identify dysplastic or cancerous lesions [ 8 , 9 ].…”

Section: Surveillance Strategy and Managementmentioning

confidence: 99%

Inflammatory Bowel Disease and Colorectal Cancer: Epidemiology, Etiology, Surveillance, and Management

Sato,

Tsujinaka,

Miura

et al. 2023

Cancers

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Patients with inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn’s disease, have an increased risk of developing colorectal cancer (CRC). Although advancements in endoscopic imaging techniques, integrated surveillance programs, and improved medical therapies have contributed to a decreased incidence of CRC in patients with IBD, the rate of CRC remains higher in patients with IBD than in individuals without chronic colitis. Patients with IBD-related CRCs exhibit a poorer prognosis than those with sporadic CRCs, owing to their aggressive histological characteristics and lower curative resection rate. In this review, we present an updated overview of the epidemiology, etiology, risk factors, surveillance strategies, treatment recommendations, and prognosis of IBD-related CRCs.

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“…However, current surveillance programs present several limitations, including low levels of patient enrollment, missed lesions (resulting in interval cancers), and uncertainties in the management of dysplasia 11 . In a 2022 review, AI Bakir et al 12 . discussed the histopathological diagnosis of IBD‐associated dysplasia and described the techniques to maximize dysplasia detection.…”

Section: Management Of Complicationsmentioning

confidence: 99%

“…11 wileyonlinelibrary.com/journal/ueg2 dysplasia. 11 In a 2022 review, AI Bakir et al 12 discussed the histopathological diagnosis of IBD-associated dysplasia and described the techniques to maximize dysplasia detection. Moreover, the review proposed a practical and standardized multidisciplinary approach for the management of patients with dysplasia.…”

Section: Management Of Complicationsmentioning

confidence: 99%

Changing paradigms in management of inflammatory bowel disease

Mao

Magro

2022

UEG Journal

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In the last decade, the prevalence of inflammatory bowel disease (IBD) has increased, both in developed and developing regions, with a marked global burden associated with disease management. 1 Our knowledge of IBD pathogenesis, diagnosis, monitoring, and treatment strategy has changed substantially over the last years. To collect the latest evidence and make it available to healthcare professionals, we, hereby, present an IBD special issue focused on the most recent monitoring and treatment innovations.

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Optimising inflammatory bowel disease surveillance and dysplasia management—Where do we stand?

Cited by 7 publications

References 73 publications

Concordance of Dye-Spraying Chromoendoscopy and Virtual Chromoendoscopy for Colonic Dysplasia Detection in Longstanding Inflammatory Bowel Disease

Concordance of Dye-Spraying Chromoendoscopy and Virtual Chromoendoscopy for Colonic Dysplasia Detection in Longstanding Inflammatory Bowel Disease

Inflammatory Bowel Disease and Colorectal Cancer: Epidemiology, Etiology, Surveillance, and Management

Changing paradigms in management of inflammatory bowel disease

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