Optimalization Of NMR Micro Imaging (1.9T, 4.7T, 7.4T) Of The Central Nervous System Of An Animal Model For Multiple Sclerosis

Abstract

Nuclear magnetic resonance (NMR) imaging of the central nervous system (CNS) is by far the most sensitive technique for the visualization of multiple sclerosis (MS) lesions. At this moment there is no clear correlation between NMR characteristics and neuropathological data. In this study, in vivo and in vitro high resolution NMR imaging was optimized in order to investigate the NMR characteristics of lesions in an animal model for MS. These characteristics will be correlated with the specific neuropathologic features of the lesions.