Optimal waist circumference cutoff value for defining the metabolic syndrome in postmenopausal Latin American women

Blümel, Juan E.; Legorreta, Deborah; Chedraui, Peter; Ayala, Félix; Bencosme, Ascanio; Danckers, Luis; Lange, Diego; Espinoza, María T.; Gómez, Gustavo; Grandia, Elena; Izaguirre, Humberto; Manrı́quez, V.; Martino, M U De; Navarro, Daysi; Ojeda, Eliana; Onatra, William; Pozzo, Estela; Prada, Mariela; Royer, Monique; Ortega, Juan; Sayegh, Fabiana; Tserotas, Konstantinos; Vallejo, María S.; Zuñiga, Cristina

doi:10.1097/gme.0b013e318231fc79

Cited by 25 publications

(7 citation statements)

References 19 publications

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“…Moreover, our data suggest that android postmenopausal women developed features of the MetS with an increased risk of CVD, as evidenced by insulin resistance, Castelli index and hypertension [5,6,8,10].…”

Section: Discussionmentioning

confidence: 98%

“…The reference values for some of the parameters are: glucose≤ 100 mg/dL, insulin from 2.6 to 24.9 uUI/ml, triglycerides≤ 150 mg/dL, total cholesterol≤200 mg/dl and HDL≥50 mg/dL, LDL≤130 mg/dL and VLDL up to 40 mg/dL [5,19,20].…”

Section: Assessment Of Biochemical Examsmentioning

confidence: 99%

“…After the menopause, the gynoid fat distribution gradually changes to an android distribution with an increased upper body fat, in the abdominal region [2]. These are associated with decreased aerobic capacity and reduced total energy expenditure [3] and may lead to the metabolic syndrome (MetS), as evidenced by androgenic obesity, insulin resistance, diabetes melittus (type II), hypertension and dyslipidemia [4,5]. According to the National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III) definition [6], MetS is diagnosed when three of the above mentioned criteria are met, and CVD is the leading cause of mortality and morbidity in postmenopausal woman [2].…”

Section: Introductionmentioning

confidence: 99%

“…Studies [8,9] have identified the menopausal transition a trigger for changes in the body fat distribution in healthy middle-aged women. Moreover, the type of body fat distribution is related to the possibility of developing metabolic disorder, mainly as androgenic obesity plays an important role in MetS [5,10].…”

Section: Introductionmentioning

confidence: 99%

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Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Paolillo

Milan

Paolillo

et al. 2013

Int J Diabetes Dev Ctries

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The aim of this study was to investigate the anthropometric, metabolic, cardiovascular and symptomatic profile in gynoid and android postmenopausal women. Forty five postmenopausal women aged 50 to 60 years were divided into two groups according to fat distribution [waist-to-hip ratio (WHR)]: gynoid group (WHR between 0.68 and 0.8; N=13) and android group (WHR>0.8; N= 32). Body composition, skinfold thickness, serum/plasma estradiol, creatinine, urea, lipid profile, glucose and insulin, maximal exercise testing and menopause rating scale (MRS) were evaluated. The android group when compared to the gynoid group showed (P<0.05): (i) higher values of body mass, BMI, waist circumference, body fat, lean mass and skinfold thickness; (ii) higher values of estradiol, triglycerides, very low-density lipoprotein (VLDL) and insulin levels with lower insulin sensitivity (%S) and greater insulin resistance (%IR) index; (iii) higher blood pressure (BP) during rest and lower maximal heart rate (HRmax) during maximal exercise testing and; (iv) higher scores of the somatic and urogenital-sexual symptoms. This study suggests that android postmenopausal women develop features that can lead to metabolic syndrome (MetS) and future cardiovascular disease (CVD), and these women may present higher scores of somatic and urogenital-sexual symptoms.

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Section: Discussionmentioning

confidence: 98%

Section: Assessment Of Biochemical Examsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Paolillo

Milan

Paolillo

et al. 2013

Int J Diabetes Dev Ctries

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“…Waist circumference is a simple valid, cost effective clinical anthropometric measure predictor for detection of MetS (9)(10)(11)(12)(13)(14)(15)(16)(17)(18). The use of WC is preferred to BMI for evaluation of abdominal adiposity (19), but the cut-off values of WC vary according to ethnicity, gender and lifestyle; therefore, population-specific cutoff points were incorporated into the definition (6,20).…”

Section: Introductionmentioning

confidence: 99%

Cut-Off Point of Waist Circumference Used for the Diagnosis of Metabolic Syndrome Among Adult Population in Ahvaz, Southwestern Iran

Shahbazian

Latifi

Nouhjah

2015

Jentashapir J Health Res

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Background: Metabolic syndrome (MetS) is a well-known risk factor for type 2 diabetes and cardiovascular disease. Waist circumference (WC) is an essential component for the diagnosis of the MetS. Objectives: The aim of this study was to compare the cut-off points of WC proposed by the international diabetes federation (IDF), adult treatment panel (ATP III), and iranian national committee of obesity (INCO) with that of the present study for predicting the MetS. Patients and Methods:This cross-sectional study was performed on 930 individuals (439 males and 491 females) aged more than 20 years living in Ahvaz City, capital of Khuzestan Province in southwestern Iran during 2009 -2010. Waist circumference cut-off values were obtained using a receiver operator characteristic curve. Optimal cut-off values were calculated by plotting the true-positive rate against the false-positive rate. Also, sensitivity, specificity, and Youden's Index were calculated. Results: The cut-off points of WC, according to a maximum sum of sensitivity plus specificity for detecting at least two components of MetS were found to be 91.5 cm and 85.5 cm in men and women, respectively. Using these values, sensitivity and specificity were 61% in men and 65% in women. The sensitivity of the male population and the specificity of the female population were found to be higher than the values proposed by IDF and ATP III. Conclusions:Optimal WC values for defining MetS were 91.5 cm and 85.5 cm in men and women, respectively. The cut-off values recommended by world organizations are not appropriate for an adult population living in Ahvaz City.

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Obesity in Latin America

Aschner

2016

Metabolic Syndrome

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Optimal waist circumference cutoff value for defining the metabolic syndrome in postmenopausal Latin American women

Abstract: A WC cutoff value of 88 cm is optimal for defining METS in this postmenopausal Latin American series.

Cited by 25 publications

References 19 publications

Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Impact of fat distribution on metabolic, cardiovascular and symptomatic aspects in postmenopausal women

Cut-Off Point of Waist Circumference Used for the Diagnosis of Metabolic Syndrome Among Adult Population in Ahvaz, Southwestern Iran

Obesity in Latin America

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