Optimal intervention strategies for cholera outbreak by education and chlorination

Abstract

Abstract. This paper discusses the control of infectious diseases in the framework of optimal control approach. A case study on cholera control was studied by considering two control strategies, namely education and chlorination. We distinct the former control into one regarding person-to-person behaviour and another one concerning person-to-environment conduct. Model are divided into two interacted populations: human population which follows an SIR model and pathogen population. Pontryagin maximum principle was applied in deriving a set of differential equations which consists of dynamical and adjoin systems as optimality conditions. Then, the fourth order Runge-Kutta method was exploited to numerically solve the equation system. An illustrative example was provided to assess the effectiveness of the control strategies toward a set of control scenarios.

Validating of Knowledge, Attitudes, and Practices Questionnaire for Prevention of COVID-19 infections among Undergraduate Students: A RASCH and Factor Analysis

“…During the COVID-19 pandemic, the science education sector has played an important role in collaboration with the health sector and other supporting fields (Bakhtiar, 2016;Barennes et al, 2010;Karlsen et al, 2015). Science education not only contributes to one's knowledge, but it also affects a person's general attitudes and practices toward infectious disease.…”

Optimal Control of Shigellosis with Cost-Effective Strategies

“…Therefore, to minimize the number of pathogens in the environment (including water sources and foods), it is essential to incorporate a rate u 2 ( t ) that caters for that case. Likewise, a success of education campaigns has been extensively reported by a number of scholars (e.g., [ 14 , 16 ]) in combating several diseases. In the current work, we also assume that public health education plays an important role in controlling shigellosis.…”

“…They used the optimal control theory to confirm the significant role played by control measures (education and treatment of water bodies) and the bacteria in the environment in the transmission dynamics as well as reduce the spread of cholera. Reference [ 14 ] studied cholera by incorporating two control strategies, namely, education and chlorination. Cost-effectiveness was also carried out, and it was noted that education was the most cost-effective strategy to curtail cholera.…”

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