Optimal Diagnosis and Treatment of Group A Streptococcal Pharyngitis

Kim, Sun Joo

doi:10.3947/ic.2015.47.3.202

Cited by 4 publications

(5 citation statements)

References 10 publications

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“…The prevalence of this type of pharyngitis varies among different age groups. It is most commonly seen in school-age children ( 7 ). In a meta-analysis conducted on the prevalence of Streptococcus pyogenes , its prevalence among all age groups was reported as 3% - 26% (pooled prevalence = 12, CI 95% = 9% - 14%) ( 4 ).…”

Section: Discussionmentioning

confidence: 99%

“…Due to the considerable overlap in symptoms and signs of streptococcal and nonstreptococcal pharyngitis, it is not often possible to diagnose the conditions clinically. A definitive diagnosis requires laboratory tests such as a throat swab culture on a sheep blood agar plate and the rapid antigen detection test (RADT) ( 6 , 7 ). Apart from acute infectious complications, GABHS pharyngitis can cause noninfectious complications such as acute rheumatic fever, rheumatic heart disease, and acute poststreptococcal glomerulonephritis ( 8 ).…”

Section: Introductionmentioning

confidence: 99%

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Streptococcal Pharyngitis in a Two-Month-Old Infant: A Case Report

Sharif

Aalinezhad

Sajadian

et al. 2016

Jundishapur J Microbiol

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IntroductionGroup A β-hemolytic Streptococcus is the most common cause of bacterial pharyngitis among 5 - 15-year-old children, but it is uncommon in children less than three years old and rarely happens in infants less than one year old.Case PresentationThe patient was a 62-day-old female infant who presented with fever and poor feeding since two days before admission. At the time of admission, the patient was febrile and ill. Upon examination, a rectal temperature of 38.5°C, multiple right-sided submandibular lymphadenopathies, pharyngeal erythema, and tonsillar exudates were detected. Twenty-four hours after the throat swab was collected and cultured, Streptococcus pyogenes grew on a sheep blood agar medium. The patient’s mother, who also experienced similar symptoms, had a positive throat swab culture for S. pyogenes.ConclusionsAlthough Streptococcal pharyngitis is rare in children less than three years old and the necessity of treatment is not well clarified, in case of streptococcal infection in parents and the occurrence of similar signs and symptoms in their child, considering S. pharyngitis as a possible differential diagnosis seems rational.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Streptococcal Pharyngitis in a Two-Month-Old Infant: A Case Report

Sharif

Aalinezhad

Sajadian

et al. 2016

Jundishapur J Microbiol

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“…However, prudent use of antimicrobial agents, guided by rapid antigen tests for pharyngitis, is important to minimize the collateral damage of unnecessary antimicrobial agents. 36 …”

Section: Gas Notorious For Its Invasiveness But Universally Susceptib...mentioning

confidence: 99%

Toxic Shock Syndrome (TSS) Caused by Group A Streptococcus: Novel Insights Within the Context of a Familiar Clinical Syndrome

Kim

2024

J Korean Med Sci

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The emergence of invasive infections attributed to group A Streptococcus (GAS) infections, has resurged since the 1980s. The recent surge in reports of toxic shock syndrome due to GAS in Japan in 2024, while sensationalized in the media, does not represent a novel infectious disease per se, as its diagnosis, treatment, and prevention are already well-established. However, due to signs of increasing incidence since 2011, further research is needed. Health authorities in neighboring countries like The Republic of Korea should not only issue travel advisories but also establish meticulous surveillance systems and initiate epidemiological studies on the genotypic variations of this disease while awaiting various epidemiological research findings from Japan.

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“…Golongan β-laktam, seperti penicillin, amoxicillin dan cephalosporin generasi pertama adalah antibiotik yang dapat digunakan dalam mengatasi infeksi bakteri Streptococcus pyogenes. Macrolide generasi baru juga dapat digunakan sebagai alternatif pilihan jika didapatkan alergi pada penicillin (Kim, 2015). Terapi yang dapat digunakan pada infeksi Pseudomonas aeruginosa adalah penicillin, gentamicin, meropenem, imipenem, atau doripenem, aztreonam, polymixin E, dan ciprofloxacin (Moore et al, 2016).…”

Section: Materials Dan Metodeunclassified

Inhibitory Activity of Allium Sativum L. Extract Against Streptococcus Pyogenes and Pseudomonas Aeruginosa

2019

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Background: One of the most common health problems is infectious diseases. Infectious disease can be caused by bacteria. There were two groups of bacteria based on the staining, Gram-positive and Gram-negative bacteria. Purpose: Antibiotics are the main therapy used in the incidence of bacterial infections. But over time, some antibiotics became resistance. Several studies have shown that garlic has an antibacterial effect. The content of allicin, ajoene, saponins, and flavonoids is found in garlic which has antibacterial properties. The antibiotic activity test of garlic was carried out on the bacteria Streptococcus pyogenes and Pseudomonas aeruginosa. The goal of this study is to investigate the antibacterial effect of Allium sativum L. extract against Streptococcus pyogenes and Pseudomonas aeruginosa. Methods: Garlic extract was made using the maceration method using 96% alcohol as the solvent. Tube dilution method elected to observe garlic antibiotic activity. This test aims to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). There were eight different concentration used, i.e. 2 grams/ml, 1 gram/ml, 0.5 gram/ml, 0.25 gram/ml, 0.125 gram/ml, 0.0625 gram/ml, 0.03125 gram/ml, and 0.015625 gram/ml. Replication is done three times. Results: In this experiment, the extract produced was turbid that MIC could not be determined and there was no momentous differentiation between before and after treatment. There was no growth of Streptococcus pyogenes in 1 gram/ml and Pseudomonas aeruginosa in 0.5 gram/ml. This number indicates the MBC for each bacteria. Conclusion: Garlic (Allium sativum L.) has an effect of bactericidal activity, it can perform as an antibacterial for Streptococcus pyogenes and Pseudomonas aeruginosa. Garlic extract was more effective for Pseudomonas aeruginosa than Streptococcus pyogenes.

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Optimal Diagnosis and Treatment of Group A Streptococcal Pharyngitis

Cited by 4 publications

References 10 publications

Streptococcal Pharyngitis in a Two-Month-Old Infant: A Case Report

Streptococcal Pharyngitis in a Two-Month-Old Infant: A Case Report

Toxic Shock Syndrome (TSS) Caused by Group A Streptococcus: Novel Insights Within the Context of a Familiar Clinical Syndrome

Inhibitory Activity of Allium Sativum L. Extract Against Streptococcus Pyogenes and Pseudomonas Aeruginosa

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