2008
DOI: 10.1364/josab.25.001312
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Optical resonances in microcylinders: response to perturbations for biosensing

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Cited by 45 publications
(44 citation statements)
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“…This effect is the basis for resonant optical biosensing. 7,10,11 The changes in the spectral properties of resonators in the presence of perturbations can be used to characterize the size and shape of the attached nanoparticles.…”
Section: Introductionmentioning
confidence: 99%
“…This effect is the basis for resonant optical biosensing. 7,10,11 The changes in the spectral properties of resonators in the presence of perturbations can be used to characterize the size and shape of the attached nanoparticles.…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, combining the dissipative and reactive sensing methods, more information of the analyte can be obtained, and those two kinds of signal may verify with each other and confirm the reliability of the detection results. Note that the linewidth change induced by the absorption loss differs from the mode broadening resulting from additional scattering loss and unresolvable splitting in the optical spectrum [26,29,53]. In this work, we thus propose and demonstrate to detect single lossy nanoparticles via the dissipative interaction with a toroidal optical microcavity which supports high-Q optical whisperinggallery modes (WGMs).…”
Section: Introductionmentioning
confidence: 99%
“…Optical microcavities featuring high-Q factors and small mode volumes, such as Fabry-Perot cavities [3], photonic crystals [4,5], microspheres [6][7][8][9], microrings [10][11][12][13][14], microtoroids [15][16][17], microbubbles [18][19][20], and microtubes [21,22] have been widely investigated in sensing applications. In general, the microcavity sensing depends mainly on reactive (i.e., dispersive) interactions, resulting in a resonance wavelength shift [23][24][25][26] or mode splitting [26,27], which essentially responds to the real part of the polarizability of the targets. Via reactive sensing, a single virus [28,29] and a single nanoparticle [30][31][32][33] have been detected experimentally.…”
Section: Introductionmentioning
confidence: 99%
“…By detecting the shift of WGMs, the ultra-sensitive size sensing can be realized [12][13][14]. In addition, the dispersion of nanoparticles will induce the mode splitting [15][16][17][18][19][20][21][22][23][24][25][26][27] or mode broadening [28][29][30], and will also cause the linewidth change [31] which can be used for size sensing as well.…”
Section: Introductionmentioning
confidence: 99%