2016
DOI: 10.1103/physrevapplied.5.024011
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Detection of Single Nanoparticles Using the Dissipative Interaction in a High-QMicrocavity

Abstract: Ultrasensitive optical detection of nanometer-scaled particles is highly desirable for applications in early-stage diagnosis of human diseases, environmental monitoring, and homeland security, but remains extremely difficult due to ultralow polarizabilities of small-sized, low-index particles. Optical whispering-gallery-mode microcavities, which can enhance significantly the light-matter interaction, have emerged as promising platforms for label-free detection of nanoscale objects. Different from the conventio… Show more

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Cited by 86 publications
(23 citation statements)
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“…In addition, PCNCs with ultra-high sensitivity, quality factor and ultra-small mode volume opens up the possibility to push the detection limit down to single nanoparticle level [44]. Furthermore, the sensitivity and detection limit can be enhanced by introducing SPR into PCNCs in the future, which has been employed in WGM cavities [68]…”
mentioning
confidence: 99%
“…In addition, PCNCs with ultra-high sensitivity, quality factor and ultra-small mode volume opens up the possibility to push the detection limit down to single nanoparticle level [44]. Furthermore, the sensitivity and detection limit can be enhanced by introducing SPR into PCNCs in the future, which has been employed in WGM cavities [68]…”
mentioning
confidence: 99%
“…5, and the detailed simulation conditions can be found in Ref. [63]. Although the magnitudes of the linewidth change and the mode shift do not fall exactly on the experimental results due to the nonuniform size distribution of the the nanorods as well as their random position on the cavity and orientation, the general trend is the same, for example, the linewidth change is larger than the mode shift at 680 nm, and vice versa at 635 nm [63].…”
Section: Resultsmentioning
confidence: 89%
“…As the wavelength increases, the real part of the particle polarizability turns from negative to positive values. When Re[α] = 0 at a wavelength close to SPR, the dipole moment of the nanoparticle has a π/2 phase difference with the evanescent field, and the coupling energy between the nanoparticle and the cavity is zero, resulting in a zero mode shift [63]. The positive mode frequency shift in Fig.…”
Section: Resultsmentioning
confidence: 98%
“…High-quality whispering gallery mode (WGM) optical resonators have emerged as a promising platform for compact and ultrahigh sensitive sensing over the past two decades [1][2][3], which have been studied theoretically and experimentally in various sensing applications, including solution and gas sensors, thermal sensors, humidity sensors, magnetometers [4][5][6][7][8][9][10][11][12]. Advantageously, WGM resonators can also detect, at a single particle level, nanoparticle, bio-molecule, and even atomic ions [13][14][15][16][17][18][19]. Based on WGM resonators, the sensing is typically realized by measuring the spectral changes in high resolution using a tunable laser or an optical spectrometer [6][7][8][9][10].…”
Section: Introductionmentioning
confidence: 99%
“…Based on WGM resonators, the sensing is typically realized by measuring the spectral changes in high resolution using a tunable laser or an optical spectrometer [6][7][8][9][10]. These spectral changes include mode shift, splitting and broadening, which is called reactive sensing [5,13,16,[20][21][22][23][24]. Alternatively, when WGM resonators detect absorptive target analytes, the probe light may be strongly absorbed and then the linewidth of WGM resonator mode is significantly broadened, which is exploited to implement the dissipative sensing [16,20].…”
Section: Introductionmentioning
confidence: 99%