Optical Performance of a Monofocal Intraocular Lens Designed to Extend Depth of Focus

Abstract

To test the performance of a new monofocal intraocular lens, intended to extend depth of focus (Tecnis® Eyhance, ICB00) (ICB-IOL), in comparison to a timetested standard monofocal IOL (Tecnis® 1-piece, ZCB00) (ZCB-IOL) of same platform and material. MethodsAssessment of the optical performance of the two IOLs was made in-vitro using an optical test bench with a model eye. The spherical aberration (SA), modulation transfer function (MTF) and the area under the MTF (MTFa) were obtained for pupil sizes ranging from 2.0mm to 5.0mm. Through-focus MTFa curves between -3.0D to +1.0D were obtained with three pupils (2.0mm, 3.0mm and 4.5 mm). Halo formation was also assessed for both lenses. ResultsThe ICB-IOL had slightly worse optical quality at its best focus (i.e., lower MTF scores at distance vision) and more negative SA than the ZCB-IOL for pupils ranging from 2.0mm up to 3.0mm.The maximum of the through-focus MTFa curve of the ICB-IOL with a 2.0mm pupil, shifted to myopic defocus of -0.50 D.For larger pupils (≥3.5 mm), there were no differences of SA, MTF scores and halo energy between the two lenses. ConclusionsThe new ICB-IOL is a modified monofocal lens with 0.50D of additional power in its central 2mm zone and more negative SA values, which induces a myopic shift of the maximum of optical quality and could improve intermediate vision.For pupils larger than 3.5mm, there were no differences between both IOLs. 3The new ICB-IOL design would produce photic phenomena comparable to a standard IOL.

Visual Performance and Optical Quality after Implantation of a New Generation Monofocal Intraocular Lens

“…The optical quality measured using the OQAS in our study was comparable between the two groups, based on the OSI, MTF cutoff, and Strehl ratio, consistent with previous reports [3]. However, few studies have analyzed the optical quality in pseudophakic eyes using the OQAS and the contributions of the material and design features of IOLs have not yet been fully characterized [11,15,16]. Higher OSI values have been observed in multifocal IOLs, with mean OSIs of 1.45 in eyes implanted with the ZCB00 and a mean of 2.50 in eyes implanted with the ZMB00 (Advanced Medical Optics, Santa Ana, CA, USA), a multifocal IOL made of hydrophobic acrylic material [11].…”

“…Furthermore, a significant correlation was observed between OSI values and glare in the multifocal group, indicating that the OSI may be a reliable index for the visual quality of multifocal IOLs. The OQAS values for the ZCB00 and ICB00 did not differ significantly, indicating similar optical qualities between the two IOLs [3,11,16].…”

“…The ZCB00 is a single-piece 6.0 mm biconvex hydrophobic acrylic monofocal IOL with an aspheric anterior surface that results in a negative spherical aberration of -0.27 µm and a translucent, continuous 360-degree posterior square edge [12,15]. The ICB00 is a newly created monofocal IOL that has equal characteristics to the ZCB00 widely preferred worldwide, except for the modified aspheric anterior surface of the optic [16]. This novel optic provides a thickness variance of 1.5 microns with a diameter of about 2 mm in the center and a continuous power profile (a continuous power increase of approximately 0.5 D from the periphery to the center of the lens), which is intended to improve vision for intermediate tasks as compared to a standard monofocal IOL [16].…”

“…The ICB00 is a newly created monofocal IOL that has equal characteristics to the ZCB00 widely preferred worldwide, except for the modified aspheric anterior surface of the optic [16]. This novel optic provides a thickness variance of 1.5 microns with a diameter of about 2 mm in the center and a continuous power profile (a continuous power increase of approximately 0.5 D from the periphery to the center of the lens), which is intended to improve vision for intermediate tasks as compared to a standard monofocal IOL [16]. The ICB00 has no diffractive rings and zones and is visually indistinguishable from the ZCB00 [8].…”

A comparison of clinical outcomes and optical performance between monofocal and new monofocal with enhanced intermediate function intraocular lenses: a case-control study

“…The unique anterior surface lies on the center deviation of the Eyhance ICB00 IOL may explain those results [ 24 ]. Previous study showed that the through-focus MTF curve of the ICB00 shifted to a myopic defocus of − 0.50 D at a 2.0 mm pupil size and the maximum MTF value was obtained at − 0.5 D defocus [ 25 ]. However, in this study, the maximum MTF value was obtained at 0.0 D defocus without myopic shift of the MTF curve at a 2.0 mm pupil size.…”