Optical fiber-based biosensors

Monk, David J.; Walt, David R.

doi:10.1007/s00216-004-2650-x

Cited by 135 publications

(76 citation statements)

References 81 publications

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“…Following classification of fiber optic biosensors based on the biological recognition element with examples is given by Monk and Walt (2004). Recent references and examples are supplemented:…”

Section: Classification Of Fiber Optic Biosensorsmentioning

confidence: 99%

Optical biosensors for food quality and safety assurance—a review

et al. 2011

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Food quality and safety is a scientific discipline describing handling, preparation and storage of food in ways that prevent food borne illness. Food serves as a growth medium for microorganisms that can be pathogenic or cause food spoilage. Therefore, it is imperative to have stringent laws and standards for the preparation, packaging and transportation of food. The conventional methods for detection of food contamination based on culturing, colony counting, chromatography and immunoassay are tedious and time consuming while biosensors have overcome some of these disadvantages. There is growing interest in biosensors due to high specificity, convenience and quick response. Optical biosensors show greater potential for the detection of pathogens, pesticide and drug residues, hygiene monitoring, heavy metals and other toxic substances in the food to check whether it is safe for consumption or not. This review focuses on optical biosensors, the recent developments in the associated instrumentation with emphasis on fiber optic and surface plasmon resonance (SPR) based biosensors for detecting a range of analytes in food samples, the major advantages and challenges associated with optical biosensors. It also briefly covers the different methods employed for the immobilization of bio-molecules used in developing biosensors.

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Section: Classification Of Fiber Optic Biosensorsmentioning

confidence: 99%

Optical biosensors for food quality and safety assurance—a review

et al. 2011

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“…The researchers also constructed magnetic microparticles containing a short piece of DNA that binds to a separate unique region of the target DNA. Optical biosensors could become a powerful tool in the imminent future for the real-time and remote detection of emerging infectious diseases (Monk and Walt, 2004). As high-end instruments, the SPR array equipped with auto-samplers and powerful data acquisition continues to play an important role in the most profitable pharmaceutical and biotechnology companies to speed up the drug discovery and development process.…”

Section: Trends and Future Possibilitiesmentioning

confidence: 99%

Biosensor technology: Technology push versus market pull

Luong

Male

Glennon

2008

Biotechnology Advances

370

178

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“…Piunno et al [33] had investigated a fiber-optic biosensor for detection of DNA hybridization using fluorescent DNA stain ethidium bromide. These biosensors didn't require traditional labeling step prior to analysis of a sample [34], but they are influenced to ambient temperature and solution ionic strength.…”

confidence: 99%

Recent advances in fiber-optic DNA biosensors

Wang¹,

Pang²,

Zhang³

2009

JBiSE

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Fiber-optic DNA biosensors are a kind of analytic setups, which convert the Waston-Crick base pairs matching duplex or Hoogsteen's triplex (T/A-T, C/G-C) formation into a readable analytical signals when functionalized singlestrands DNA (ssDNA) or double-strands DNA (dsDNA) of interest are immobilized on the surface of fiber-optic hybrids with target DNA or interacts with ligands. This review will provide the information about the fiber-optic DNA biosensors classified into two categories depending on the end fiber and side fiber with or without the labels-label-free fiber-optic DNA biosensors and labeled fiber-optic DNA biosensor in recent years. Both are dissertated, and emphasis is on the label-free fiber-optic DNA biosensors. Fiber-optic DNA biosensors had got great progresses because fiber-optic has more advantages over the other transducers and are easily processed by nanotechnology. So fiberoptic DNA biosensors have increasingly attracted more attention to research and develop the new fiber-optic DNA biosensors that integrated with the "nano-bio-info" technology for in vivo test, single molecular detection and on-line medical diagnosis. Finally, future prospects to the fiber-optic DNA biosensors are predicted.

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Optical fiber-based biosensors

Cited by 135 publications

References 81 publications

Optical biosensors for food quality and safety assurance—a review

Optical biosensors for food quality and safety assurance—a review

Biosensor technology: Technology push versus market pull

Recent advances in fiber-optic DNA biosensors

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