Optical, electrochemical and catalytic methods for in-vitro diagnosis using carbonaceous nanoparticles: a review

Wang, Yi; Xia, Yunsheng

doi:10.1007/s00604-018-3110-1

Cited by 30 publications

(16 citation statements)

References 268 publications

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“…However, the eukaryote cell surface is able to absorb many different particles from the surroundings through endocytosis or phagocytosis, making it easier for the potential toxic NPs to penetrate and exert their harmful effects [ 65 ]. For instance, Wang et al [ 66 ] described several parameters that determine how NPs are absorbed in seaweed cells, especially highlighting the importance of the NP size for entering through the pores of the cell wall (5–20 nm), the components that may help in absorption (glycoproteins and polysaccharides) and the membrane modifications due to cellular stage. Furthermore, Wang et al also described how the environment and its changes (such as pH variations) affect this absorption process.…”

Section: Environmental Negative Impactmentioning

confidence: 99%

Environmental Impact of Nanoparticles’ Application as an Emerging Technology: A Review

et al. 2020

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The unique properties that nanoparticles exhibit, due to their small size, are the principal reason for their numerous applications, but at the same time, this might be a massive menace to the environment. The number of studies that assess the possible ecotoxicity of nanomaterials has been increasing over the last decade to determine if, despite the positive aspects, they should be considered a potential health risk. To evaluate their potential toxicity, models are used in all types of organisms, from unicellular bacteria to complex animal species. In order to better understand the environmental consequences of nanotechnology, this literature review aims to describe and classify nanoparticles, evaluating their life cycle, their environmental releasing capacity and the type of impact, particularly on living beings, highlighting the need to develop more severe and detailed legislation. Due to their diversity, nanoparticles will be discussed in generic terms focusing on the impact of a great variety of them, highlighting the most interesting ones for the industry.

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Section: Environmental Negative Impactmentioning

confidence: 99%

Environmental Impact of Nanoparticles’ Application as an Emerging Technology: A Review

et al. 2020

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“…Nanoparticles, generally characterized by submicronic (<1 µm) systems of metallic or organic materials, offer broad applications in various fields including tumor detection, imaging, diagnosis and treatment 56 . Several types of nanoparticles, such as carbonaceous, Prussian blue, or paramagnetic nanoparticles are available for in vitro diagnosis based on their peroxidase-like activity or function as enzyme carriers 57 , 58 and in vivo diagnosis as carriers of contrast agents 59 , 60 . In addition to diagnosis, their current applications in cancer treatment have gained widespread interest.…”

Section: Discussionmentioning

confidence: 99%

Ferumoxytol-β-glucan Inhibits Melanoma Growth via Interacting with Dectin-1 to Polarize Macrophages into M1 Phenotype

Liu¹,

Xu²,

Li³

et al. 2021

Int. J. Med. Sci.

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Background: Regulating the polarization of macrophages to antitumor M1 macrophages is a promising strategy for overcoming the immunosuppression of the tumor microenvironment for cancer therapy. Ferumoxytol (FMT) can not only serve as a drug deliver agent but also exerts anti-tumor activity. β-glucan has immuno-modulating properties to prevent tumor growth. Thus, a nanocomposite of FMT surface-coated with β-glucan (FMT-β-glucan) was prepared to explore its effect on tumor suppression. Methods:Male B16F10 melanoma mouse model was established to explore the antitumor effect of FMT-β-glucan. The viability and apoptotic rates of B16F10 cells were detected by cell counting kit-8 and Annexin-V/PI experiments. The levels of M1 markers were quantified by quantitative reverse transcription-polymerase chain reaction and enzyme linked immunosorbent assay. Phagocytic activity and intracellular reactive oxygen species (ROS) in macrophages were evaluated by the neutral red uptake assay and flow cytometry, respectively. Small interfering RNA (siRNA) transfection was applied to knock down the Dectin-1 gene in RAW 264.7 cells.Results: FMT-β-glucan suppressed tumor growth to a greater extent and induced higher infiltration of M1 macrophages than the combination of FMT and β-glucan (FMT+β-glucan) in vivo. In vitro, supernatant from FMT-β-glucan-treated RAW 264.7 cells led to lower cell viability and induced more apoptosis of B16F10 cells than that from the FMT+β-glucan group. Moreover, FMT-β-glucan boosted the expression of M1 type markers, and increased phagocytic activity and ROS in RAW 264.7 cells. Further research indicated that FMT-β-glucan treatment promoted the level of Dectin-1 on the surface of RAW 264.7 cells and that knockdown of Dectin-1 abrogated the phosphorylation levels of several components in MAPK and NF-κB signaling. Conclusion:The nanocomposite FMT-β-glucan suppressed melanoma growth by inducing the M1 macrophage-activated tumor microenvironment.

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“…For complete of discussion, Table 2 25‐206 summarized all of the discussed articles on the detection of bacterial. It is important to point out that, there is other reports in this research area …”

Section: Biosensing Based On Type Of Bacteriamentioning

confidence: 91%

Recent progress and challenges on the bioassay of pathogenic bacteria

2020

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The present review (containing 242 references) illustrates the importance and application of optical and electrochemical methods as well as their performance improvement using various methods for the detection of pathogenic bacteria. The application of advanced nanomaterials including hyper branched nanopolymers, carbon‐based materials and silver, gold and so on. nanoparticles for biosensing of pathogenic bacteria was also investigated. In addition, a summary of the applications of nanoparticle‐based electrochemical biosensors for the identification of pathogenic bacteria has been provided and their advantages, detriments and future development capabilities was argued. Therefore, the main focus in the present review is to investigate the role of nanomaterials in the development of biosensors for the detection of pathogenic bacteria. In addition, type of nanoparticles, analytes, methods of detection and injection, sensitivity, matrix and method of tagging are also argued in detail. As a result, we have collected electrochemical and optical biosensors designed to detect pathogenic bacteria, and argued outstanding features, research opportunities, potential and prospects for their development, according to recently published research articles.

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Optical, electrochemical and catalytic methods for in-vitro diagnosis using carbonaceous nanoparticles: a review

Cited by 30 publications

References 268 publications

Environmental Impact of Nanoparticles’ Application as an Emerging Technology: A Review

Environmental Impact of Nanoparticles’ Application as an Emerging Technology: A Review

Ferumoxytol-β-glucan Inhibits Melanoma Growth via Interacting with Dectin-1 to Polarize Macrophages into M1 Phenotype

Recent progress and challenges on the bioassay of pathogenic bacteria

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