Optical coherence tomography in gynecology: a narrative review

Kirillin, Mikhail; Мотовилова, Т. М.; Shakhova, Natalia M.

doi:10.1117/1.jbo.22.12.121709

Cited by 16 publications

(12 citation statements)

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In recent years, noninvasive imaging technologies, such as fluorescence, OCT, Doppler OCT, ultrasound, and photoacoustic imaging, have been developed to provide morphology and molecular contrast of biological tissue . Among them, OCT has the advantage over histologic tissue analysis (obtained by biopsy) in acquiring high resolution, microscopic images with a non‐invasive approach . Despite demonstrated success in various other medical fields, it has only undergone limited use in gynecology.…”

Section: Introductionmentioning

confidence: 99%

1.7 micron optical coherence tomography for vaginal tissue characterization in vivo

Sudol

Miao

et al. 2018

Lasers Surg Med

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

1.7 micron optical coherence tomography for vaginal tissue characterization in vivo

Sudol

Miao

et al. 2018

Lasers Surg Med

View full text Add to dashboard Cite

show abstract

“…Despite significant global use of OCT in many fields of medicine [49][50][51][52][53], in urology, our study demonstrated the first use of this technique for examining the urethra [36]. This paper shows that the introduction of new technology-CP OCT-in conjunction with TVUS allows verification of tissue changes and assessment of the structures of the connective tissue matrix of the lower urinary tract at the level of their architectonics.…”

Section: Discussionmentioning

confidence: 80%

“…We proceeded from the results of our previous study [36], where the morphology of the female urethra was analyzed on cadaveric material and compared with CP OCT images. This fact and numerous studies on CP OCT visualization of mucous membranes in health and pathology [30,31,52,61,62] afford ground for confidence in the interpretation of CP OCT features, such as changes in the epithelium thickness and the state of connective tissue.…”

Section: Discussionmentioning

confidence: 99%

New Approaches in the Study of the Pathogenesis of Urethral Pain Syndrome

et al. 2020

View full text Add to dashboard Cite

Introduction: Urethral pain syndrome (UPS) is still a pathology in which the diagnosis is formulated as a “diagnosis of exclusion”. The exact pathogenetic mechanisms are not yet fully understood and clear recommendations for the prevention and treatment of UPS are absent. Methods and Participants: A clinical and laboratory evaluation of 55 patients with established UPS included history taking, basic laboratory tests (e.g., complete blood count and clinical urine test), physical examination, uroflowmetry, and cystourethroscopy. Additionally, transvaginal ultrasound (TVUS) with compression elastography and cross-polarization optical tomography (CP OCT) were performed in 24 and 33 patients with UPS, respectively. The control group consisted of 14 patients with no complaints from the urinary system. Results: TVUS showed an expansion in the diameter of the internal lumen of the urethra, especially in the proximal region compared with the norm. Compression elastography revealed areas with increased stiffness (presence of fibrosis) in urethral and surrounding tissues. The performed CP OCT study showed that in UPS, the structure of the tissues in most cases was changed: trophic alterations in the epithelium (hypertrophy or atrophy) and fibrosis of underlying connective tissue were observed. The proximal fragment of the urethra with UPS underwent changes identical to those of the bladder neck. Conclusion: This paper showed that the introduction of new technology—CP OCT—in conjunction with TVUS will allow verification of structural changes in tissues of the lower urinary tract at the level of their architectonics and will help doctors understand better the basics of the UPS pathogenesis.

show abstract

“…Despite significant global use of OCT in many fields of medicine [29][30][31][32][33], in urology, ours was the first use of this technique for examining the urethra [22]. This paper shows that the introduction of 2.64 mm, respectively [27].…”

Section: Discussionmentioning

confidence: 81%

New Findings in the Study of the Pathogenesis of Urethral Pain Syndrome

Streltsova¹,

Kuyarov²,

Molvi³

et al. 2020

Preprint

View full text Add to dashboard Cite

Urethral pain syndrome (UPS) is still a pathology in which the diagnosis is formulated as a "diagnosis of exclusion". The exact pathogenetic mechanisms are not yet fully understood and clear recommendations for the prevention and treatment of UPS are absent. The goal of the study was to assess the condition of the tissues in the female urethra in UPS, by using transvaginal ultrasound (TVUS) and cross-polarization optical tomography (CP OCT). TVUS showed an expansion in the diameter of the internal lumen of the urethra, especially in the proximal region compared with the norm. Compression elastography revealed areas with increased stiffness (presence of fibrosis) in urethral and surrounding tissues. When studied with CP OCT it was shown that with UPS, the structure of the tissues in most cases was changed: trophic alterations in the epithelium (hypertrophy or atrophy) and fibrosis of underlying connective tissue were observed. The proximal fragment of the urethra with UPS underwent changes identical to those of the bladder neck. This paper showed that the introduction of new technology — CP OCT — in conjunction with TVUS will allow verification of structural changes in tissues of the lower urinary tract at the level of their architectonics and will help doctors understand better the basics of the UPS pathogenesis.

show abstract

Optical coherence tomography in gynecology: a narrative review

Cited by 16 publications

References 79 publications

1.7 micron optical coherence tomography for vaginal tissue characterization in vivo

1.7 micron optical coherence tomography for vaginal tissue characterization in vivo

New Approaches in the Study of the Pathogenesis of Urethral Pain Syndrome

New Findings in the Study of the Pathogenesis of Urethral Pain Syndrome

Contact Info

Product

Resources

About