Optical coherence tomography imaging of colonic crypts in a mouse model of colorectal cancer

Welge, Weston A.; Barton, Jennifer K.

doi:10.1117/12.2211963

Cited by 1 publication

(1 citation statement)

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“…OCT imaging revealed a fine layer of lower scattering that is not evident in histology which may not have been completely ablated. The use of optical properties derived via OCT to diagnose and visualize cancerous lesions is also of clinical importance [42,43]. These data are particularly useful when assessing antenna performance and offer advantages over histology methods.…”

Section: Discussionmentioning

confidence: 99%

Quantifying optical properties with visible and near-infrared optical coherence tomography to visualize esophageal microwave ablation zones

Niemeier

Etoz

Gil

et al. 2018

Biomed. Opt. Express

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Abstract:Microwave ablation is a minimally invasive image guided thermal therapy for cancer that can be adapted to endoscope use in the gastrointestinal (GI) tract. Microwave ablation in the GI tract requires precise control over the ablation zone that could be guided by high resolution imaging with quantitative contrast. Optical coherence tomography (OCT) provides ideal imaging resolution and allows for the quantification of tissue scattering properties to characterize ablated tissue. Visible and near-infrared OCT image analysis demonstrated increased scattering coefficients (μ s ) in ablated versus normal tissues (Vis: 347.8%, NIR: 415.0%) and shows the potential for both wavelength ranges to provide quantitative contrast. These data suggest OCT could provide quantitative image guidance and valuable information about antenna performance in vivo. van Leeuwen, "Quantitative attenuation analysis for identification of early Barrett's neoplasia in volumetric laser endomicroscopy," J.

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Section: Discussionmentioning

confidence: 99%