Optical chirality sensing using macrocycles, synthetic and supramolecular oligomers/polymers, and nanoparticle based sensors

Abstract

Optical sensors that respond to enantiomeric excess of chiral analytes are highly demanded in chirality related research fields and demonstrate their potential in many applications, for example, screening of asymmetric reaction products. Most sensors developed so far are small molecules. This Tutorial Review covers recent advances in chirality sensing systems that are different from the traditional small molecule-based sensors, by using macrocycles, synthetic oligomers/polymers, supramolecular polymers and nanoparticles as the sensors, in which supramolecular interactions operate.

Triple Noncovalent‐Interaction‐Containing Supramolecular Polymer Vesicle Chemosensors with Dynamically Tunable Detection Ranges

“…Therefore, these polymers are much easier to design and synthesize than those of traditional covalent polymers, which may further facilitate the design and optimization of CSs . For example, supramolecular polymer chemosensors (SPCSs) can offer the structural diversity and stimuli‐responsive properties of the building blocks and the higher local concentration of binding sites . However, SPCSs are generally constructed using only one kind of noncovalent interaction.…”

Second‐Generation Tris(2‐pyridylmethyl)amine–Zinc Complexes as Probes for Enantiomeric Excess Determination of Amino Acids

“…[1] In this context, particular attention has been devoted to the determination of enantiomeric excess (ee) by using optical methods. [5][6][7][8] Among the different techniques, electronic circular dichroism is dominant, even though alternative techniques have been extensively studied as well. [5][6][7][8] Among the different techniques, electronic circular dichroism is dominant, even though alternative techniques have been extensively studied as well.…”

Water-soluble host–guest system from β-cyclodextrin as a fluorescent sensor for aluminium ions: synthesis and sensing studies

“…Among the water solubility sensor's research methods, the fabrication of host-guest systems is an significant technique. Among the host-guest systems, β-cyclodextrin (β-CD) is an important host molecule owing to its unique structure, which exhibits high water solubility, low toxicity and good biocompatibility and have been widely used in many fields like medicine, chemical engineering and separation technique et al [24][25][26] And that the β-cyclodextrin derived hostguest system has been have related report, [27][28][29] but such hostguest fluorescent sensors are relatively scarce in recent years. In addition, the diversity of organic molecules can generate various host-guest system.…”