Optical Biomedical Diagnostics

Viktorovich, Tuchin Valeriy

doi:10.18500/1817-3020-2005-5-1-39-53

Cited by 21 publications

(26 citation statements)

References 47 publications

(130 reference statements)

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“…Local optical inhomogeneities in tissues, as a rule, are areas that differ in the values of the absorption and scattering coefficient from the surrounding tissues. The reason for the formation of such areas can be inflammatory and pathological processes, functional changes in tissues, leading to a local change in blood circulation [3,4]. Local changes in the values of the absorption and scattering coefficient lead to the appearance of a contrast of inflammation, pathology or altered blood supply areas relative to the surrounding tissues in the images of the visible and near infrared range [1,2].…”

Section: Methodsmentioning

confidence: 99%

Metrological Assurance of Infrared Transillumination of Biological Tissues

Колпаков

Muravskaya

2022

J. Phys.: Conf. Ser.

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The article is devoted to the urgent scientific and technical problem of developing metrological assurance for hardware and software infrared transillumination systems designed to visualize the internal structure of biological tissues in order to detect early stages, measure and control the dynamics of pathological processes. As part of solving this problem, at the Department of Biomedical Technical Systems of the Bauman Moscow State Technical University a set of measures that simulate the optical properties of biological tissues, containing local optical in homogeneities was developed. Experimental studies were carried out using the developed measures, as a result of which the possibility of visualizing the structural in homogeneities of biological tissues using the method of infrared transillumination was shown. The approved method for the manufacture of measures can be used to simulate the optical properties of biological tissues in the course of subsequent studies and further stages of the development of metrological assurance for hardware and software complexes of infrared transillumination.

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Section: Methodsmentioning

confidence: 99%

Metrological Assurance of Infrared Transillumination of Biological Tissues

Колпаков

Muravskaya

2022

J. Phys.: Conf. Ser.

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“…SERS imaging is one of the most promising methods for detecting tumor boundaries in cancer surgery. Among other techniques like magnetic resonance imaging [1], fluorescent imaging [2, 3] and PET/CT [4], SERS provides micrometer‐scale resolution, high contrast and low background signal under excitation in NIR region within the biotissue transparency window [5]. The basis of the imaging technology is fond on the so‐called SERS tags [6, 7], which are metal nanoparticles with adsorbed or incorporated Raman‐active molecules (dyes, aromatic molecules, etc.).…”

Section: Introductionmentioning

confidence: 99%

Improving SERS bioimaging of subcutaneous phantom in vivo with optical clearing

Khlebtsov

Буров

Pylaev

et al. 2021

Journal of Biophotonics

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Surface‐enhanced Raman scattering (SERS) has proven to be a promising technique for different types of imaging including preoperative and intraoperative in vivo tumor visualization. However, the strong scattering of the turbid tissue limits its use in subcutaneous areas. In this article, we used an optical clearing technique to improve the SERS signal from a subcutaneous tumor phantom. The phantom is a 2 mm sphere of calcium alginate with incorporated petal‐like gap‐enhanced Raman tags. The use of optical clearing increases the SERS signal target‐to‐background ratio for 5 times and allow to decrease the total imaging time for at least 10 times. In addition, SERS imaging assisted with optical clearing made it possible to more precisely determine the shape and boundaries of the implanted phantom. The combination of optical clearing and SERS is a promising strategy for the clinical imaging of subcutaneous objects that are usually shielded by dermal tissue.

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“…The development of optical and optoelectronic non-invasive means of diagnosis and research of opportunities for their effective use, in particular, to assess the structural condition of the tissue area in normal and pathologically is an actual problem of modern biomedicine [1,2]. A variety of pathological tissue area neoplasms forced to seek new approaches to conditioning, differentiation, and diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Optoelectronic Biomedical Systems for Noninvasive Treatment and Control with Informated Support in Solutions

Hryhoriy¹,

Zenon²,

Ivakh³

et al. 2015

Optoelectronics - Materials and Devices

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The chapter presents the development of an optical-electronic system with informated support in doctor solutions for its application in hematology, otorhinolaryngology, and dermatology. With the purpose of improving the quality of treatment by the perfection of the technology, the introduction of new contact lenses controls the experimental researches of spectrums of different objects and uses an optical-electronic system for the control of blood during and after the process of photopheresis. Optoelectronic systems for the treatment of ear noise by method of sedation with the use of optical bio-impact on the human psycho-physical condition through visual receptors with a special light medical information program. The proposed specialized opticalelectronic system for dermatology allowed to significantly reduce the length of time on the process of diagnosis, provide a rapid process and expand diagnostic capabilities for the identification of detected pathologies.

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Optical Biomedical Diagnostics

Cited by 21 publications

References 47 publications

Metrological Assurance of Infrared Transillumination of Biological Tissues

Metrological Assurance of Infrared Transillumination of Biological Tissues

Improving SERS bioimaging of subcutaneous phantom in vivo with optical clearing

Optoelectronic Biomedical Systems for Noninvasive Treatment and Control with Informated Support in Solutions

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