Optic Nerve Ultrasound Evaluation in Idiopathic Intracranial Hypertension

Bernardo, Maddalena De; Vitiello, Livio; Pascale, Ilaria De; Capasso, Luigi; Cornetta, Palmiro; Rosa, Nicola

doi:10.3389/fmed.2022.845554

Cited by 16 publications

(9 citation statements)

References 43 publications

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“…The most common symptoms are severe headache and papilledema which can lead to visual loss. Ultrasound scans of the optic nerve are a reliable diagnostic test [ 142 ]. Magnetic resonance elastography has detected changes in the pituitary position and increase in brain stiffness in patients with IIH [ 143 ].…”

Section: Neurological Disordersmentioning

confidence: 99%

A year in review: brain barriers and brain fluids research in 2022

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Jones

Hamilton

et al. 2023

Fluids Barriers CNS

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This aim of this editorial is to highlight progress made in brain barrier and brain fluid research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers (choroid plexus and meninges), signaling within the neurovascular unit and elements of the brain fluid systems. It further discusses how brain barriers and brain fluid systems are impacted in CNS diseases, their role in disease progression and progress being made in treating such diseases.

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Section: Neurological Disordersmentioning

confidence: 99%

A year in review: brain barriers and brain fluids research in 2022

Keep

Jones

Hamilton

et al. 2023

Fluids Barriers CNS

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“…In light of these observations, we decided to check if this asymmetry is also present with the so-called “standardized” A-scan technique, or if the reported asymmetry is related to the poor reliability of this technique [ 13 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

A-Scan Ultrasonographic Evaluation of Patients with Idiopathic Intracranial Hypertension: Comparison of Optic Nerves

Rosa

Bernardo

Stasi

et al. 2022

JCM

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Background: To evaluate the interocular optic nerve diameter (ONDs) asymmetry in patients with idiopathic intracranial hypertension (IIH) utilizing the A-scan ultrasound technique. Methods: Thirty-seven patients diagnosed with IIH were recruited from outpatients referred to the University Eye Unit between June 2014 and December 2021. Patients with optic disc pseudoedema or edema caused by other conditions were excluded. All patients with negative neuroimaging for intracranial space-occupying masses underwent standardized A-scan measurement of the OND in the primary gaze and lateral position (30 degrees test). Results: Mean, median, standard deviation, the minimum and maximum value of the two eyes at 0 degrees and the difference between the left and right thicker and thinner ONDs were measured. The two-tailed paired student t-test between the two eyes was performed using SPSS software. A statistically significant difference (p-value <0.001) between the two eyes, without a side prevalence, was found. Conclusions: Due to the differences between the ONDs of both eyes, we propose to use the mean of the ONDs between the left and right eyes at 0 degrees with the standardized A-scan diagnostic technique for a better follow-up of patients with IIH.

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“…First of all, the authors utilized the B scan probe to perform the ONSD measurements: B scan is very sensitive in detecting small optic nerve calcifications as it happens in cases of optic nerve drusen 2 but is not so reliable in case of measurements. 3,4 In fact, as the authors correctly stated, ranges for predicting raised ICP with ONSD differ in the different studies.…”

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confidence: 99%