Optic atrophy, necrotizing anterior scleritis and keratitis presenting in association with Streptococcal Toxic Shock Syndrome: a case report

Παπαγεωργίου, Κ.; Ioannidis, Alexander S; Andreou, Petros; Sinha, Asru K.

doi:10.1186/1752-1947-2-69

Cited by 6 publications

(3 citation statements)

References 6 publications

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“… 20 Albeit less commonly, there have been rare reports of additional ocular consequences of TSS, including optic neuropathy, necrotizing anterior scleritis, and keratitis in streptococcal TSS, and vertical gaze palsy in the setting of staphylococcal TSS. 21 , 22 …”

Section: Discussionmentioning

confidence: 99%

Novel case of an adult with toxic shock syndrome following COVID-19 infection

Feng¹,

Armenti²,

Albin³

2020

American Journal of Ophthalmology Case Reports

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Purpose To report a case of an adult who developed toxic shock syndrome following COVID-19 infection. Observations A 28-year-old female tested positive for COVID-19. 19 days later, she developed a fever, rash and a burning sensation in both eyes. Her examination revealed mild ocular inflammation with bilateral eyelid and conjunctival involvement. Skin biopsy favored a diagnosis of toxic shock syndrome. She was initiated on corticosteroid eye drops and her ocular symptoms resolved three days later. Conclusion and importance Toxic shock syndrome is almost always associated with conjunctival inflammation. To our knowledge, this is the first report of an adult patient with toxic shock syndrome following COVID-19 infection. The association between toxic shock syndrome and COVID-19 is unclear; however, patients should be vigilant for symptoms as toxic shock syndrome can progress rapidly and cause multi-organ failure.

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Section: Discussionmentioning

confidence: 99%

Novel case of an adult with toxic shock syndrome following COVID-19 infection

Feng¹,

Armenti²,

Albin³

2020

American Journal of Ophthalmology Case Reports

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“… 3 Although keratic infiltrates were not described as a feature in these reports, another report described a woman with necrotizing keratitis in the context of PSU. 4 …”

Section: Discussionmentioning

confidence: 99%

Poststreptococcal keratouveitis associated with group C streptococcus pharyngitis

Nataneli

Aguilera²,

Rosenbaum³

et al. 2011

OPTH

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PurposeTo report the first case of poststreptococcal syndrome uveitis (PSU) in association with group C streptococcus (GCS).Patients and methodsChart review of a 24-year-old man who presented with bilateral ocular redness, pain, and photophobia for 5 days and “white rings” around his eyes for a duration of 3 days. The patient further reported fever and sore throat in the preceding week. Slit-lamp examination showed bilateral keratouveitis. A thorough uveitis workup, antistreptolysin O (ASLO) titer, and throat culture were obtained. The patient was treated with frequent topical steroids and systemic doxycycline. The uveitis and keratitis subsided over the next few weeks, leaving extensive peripheral keratolysis.ResultsThe results of laboratory diagnostic testing revealed an elevated ASLO, C-reactive protein, as well as HLA-B27 positivity. Throat cultures grew beta-hemolytic GCS; group A streptococcus was culture negative.ConclusionGCS pharyngitis may be a causative organism of PSU.

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“…The absence of anterior segment findings rules out ulcerative keratitis and anterior necrotizing scleritis. 13 Also, based on Laura' s report that Mary' s "blue eyes were still beautiful…", 1 (ie, no noticeable abnormalities), pan-ophthalmic or orbital processes such as endophthalmitis or orbital cellulitis are implausible.…”

Section: So Why Did Mary Go Blind?mentioning

confidence: 99%