Opposite stereoselectivity of two plasma binding proteins for isradipine (PN 200-110)

Oravcová, Jana; Sojková, Dagmar; Trnovec, T.

doi:10.1016/0928-0987(95)00002-u

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1999

2022

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Cited by 3 publications

(1 citation statement)

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“…It has been clearly established that the presence of fatty acids in albumin increases its non-specific binding, thus an essentially fatty acid free HSA sample-the brand A 1887 (Sigma, St Louis, MO, USA)-was employed in several studies (Sebille et al, 1978;Thuaud et al, 1983;Bree et al, 1986;Oravcová et al, 1991aOravcová et al, , 1995aOravcová et al, ,b, 1996a.…”

Section: Hsamentioning

confidence: 99%

The Hummel–Dreyer method: impact in pharmacology

Šoltés

2003

Biomedical Chromatography

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Reviews devoted to drug-protein binding present mostly a variety of analytical methods applied to studying the unique process when the protein reversibly binds a low-molecular-weight substance-the drug. This report, however, reviews the great majority of papers presenting the application of one particular method introduced by Hummel and Dreyer in 1962: Measurement of protein-binding phenomena by gel filtration. The main criterion in reviewing published papers was the application of the Hummel-Dreyer method when the counterpart substances were the drug and the human plasma protein.

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