Opioid Dependence

Benich, Joseph J.

doi:10.1016/j.pop.2010.11.005

Cited by 10 publications

(4 citation statements)

References 34 publications

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“…Furthermore, the transactions involving drugs may be higher risk than non-drug/survival sex transactions given that a higher proportion report other sexual risk behaviors such as concurrent partnerships and are more likely to be HIV-positive. Transactions involving methamphetamine (and other club drugs) are not surprising, though it should be noted that a non-trivial proportion also reported transactions involving prescription opioids/sedatives, drugs that have a more intense withdrawal syndrome that can motivate sexual exchange behaviors [34]. Regardless of the type of drug used, it is important to continue to recognize the role of substance use treatment in STI/HIV prevention.…”

Section: Discussionmentioning

confidence: 99%

Transactional Sex among Men Who Have Sex with Men: Differences by Substance Use and HIV Status

et al. 2018

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Exchanging money, drugs, and other goods for sex has been associated with sexual risk behaviors and increased STIs/HIV. While female sex work is well described, data on men who exchange sex for money or goods are more limited. This paper examined the prevalence and correlates of transactional sex among young men who have sex with men, especially focusing on substance use and HIV status. We conducted a cohort study of 511 participants recruited between August 2014 and December 2017 in Los Angeles, CA. Eligible participants were: (1) between 18 and 45 years of age; (2) male; and (3) if HIV-negative, reported condomless anal intercourse with a male partner in the past 6 months. By design, half were HIV-positive and half HIV-negative. At baseline and semi-annual follow-up visits, computer-assisted self-interviews were used to collect information on demographics, sexual behaviors including transactional sex which was defined as exchange of money, drugs, or a place to stay for anal intercourse. Laboratory testing was conducted for current STI/HIV status. The average age of participants was 31.4 years with 43% identifying as African American, followed by 36% as Hispanic/Latino. The prevalence of recent transactional sex across 1486 study visits was 17% (n = 255), with 74% of those reporting exchanging sex for drugs. The prevalence of transactional sex was higher among those who reported unstable housing (32 vs. 11%; p value < .01), concurrent sexual partnerships (26 vs. 9%; p value < .01), and transgender sex partners (40 vs. 15%; p value < .01). Those who reported receiving money, drugs, or shelter for sex were also more likely to report giving money, drugs, shelter for sex than men who did not report exchange sex (77 vs. 11%; p value < .01). Based on multivariable analyses after adjusting for age and race/ethnicity, HIV viral load was independently associated with transactional sex [adjusted odds ratio (AOR) = 1.4; 95% confidence interval (CI) 1.1-1.7) per log increase]. Additionally, those testing positive for an STI were nearly twice as likely to report transactional sex as compared to those without STIs (AOR = 1.9; 95% CI 1.2-3.5). These findings underscore the relatively high prevalence of transactional sex and its potential role in ongoing HIV transmission among this cohort of high-risk HIV-negative and HIV-positive men who have sex with men.

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Section: Discussionmentioning

confidence: 99%

Transactional Sex among Men Who Have Sex with Men: Differences by Substance Use and HIV Status

et al. 2018

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“…The symptoms of POIS are similar to those of “opioid withdrawal syndrome,” which includes physical (flu‐like symptoms, perspiration, and rhinitis) and psychological symptoms (anxiety, depression, and difficulty concentrating). These symptoms can last 2–7 days [15]. Opioids are involved in mediation of positive affective states generated by the execution of sexual behavior [16].…”

Section: Discussionmentioning

confidence: 99%

Postorgasmic Illness Syndrome (POIS) in a Chinese Man: No Proof for IgE-Mediated Allergy to Semen

Jiang

et al. 2015

The Journal of Sexual Medicine

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Introduction Postorgasmic illness syndrome (POIS) is a rarely described syndrome characterized by transient flu-like symptoms and cognition disorders. Recent studies suggest that immunogenic reactivity to autologous semen is the underlying mechanism in POIS. However, there are no data published on immunoglobulin E (IgE)-mediated allergy to autologous semen in men without POIS. Aim The purpose of the current work was to characterize the first diagnosed POIS patient in China and to study the allergic response of autologous semen in the affected patient and in three healthy males. Methods Specific IgE was tested with seminal fluid and common perennial aeroallergens in vitro. Skin prick tests and intracutaneous tests with autologous diluted semen were performed in the patient and three healthy donors. The pattern of IgE reactivity to patient's semen was identified using immunoblotting and ELISA. Main Outcome Measure Clinical features of POIS, skin reactions with autologous diluted seminal fluid, and the IgE reactivity patterns of immunoblotting and ELISA in vitro. Results A patient was diagnosed with POIS. The patient complained of lifelong premature ejaculation symptoms and allergic rhinitis. Routine laboratory and hormonal assessments were generally within normal range. The patient had a positive skin test with his own semen. Three healthy donors also showed positive skin tests. No semen-specific IgE to autologous semen was detected in the serum of the affected patient or healthy males. Conclusions This is the first report of a man with POIS in China. He had positive skin reactions after injection of autologous seminal fluid but no detectable serum concentrations of specific IgE antibodies. IgE-mediated semen allergy in men may not be the potential mechanism of POIS.

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“…Benzodiazepinler de yoksunluk dönemindeki aşırı sıkınıtı için faydalı olabilirler. Buprenorfin μ-opiyat reseptörleri için yüksek afinite gösteren parsiyel agonisttir ve hem yoksunluk döneminde hemde idame tedavisinde kullanılabilinir (35,36).…”

Section: Yoksunlukunclassified

Approaches to Substance Abusers in an Emergency Setting

Şengül¹,

Serinken²,

Büber³

et al. 2013

JAEM

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Substance dependency is a serious problem that should be taken into consideration in an emergency service. Patients with substance dependence are seen by emergency services in many different clinical situations. Studies show that emergency service personnel are faced with substance-dependents most frequently. For this reason, substance dependency is a very important topic for emergency service personnel. A number of approaches have been reported regarding substance dependency treatment in the literature. The aim of this article is to review research about the management of substance dependency in an emergency service. (JAEM 2013; 12: 215-9)

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Opioid Dependence

Cited by 10 publications

References 34 publications

Transactional Sex among Men Who Have Sex with Men: Differences by Substance Use and HIV Status

Transactional Sex among Men Who Have Sex with Men: Differences by Substance Use and HIV Status

Postorgasmic Illness Syndrome (POIS) in a Chinese Man: No Proof for IgE-Mediated Allergy to Semen

Approaches to Substance Abusers in an Emergency Setting

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