Ophthalmologic Findings in Acquired Immune Deficiency Syndrome (AIDS)

Khadem, May; Kalish, Steve B.; Goldsmith, J.; Fetkenhour, Carl L.; O'Grady, Richard B.; Phair, John P.; Chrobak, Martin

doi:10.1001/archopht.1984.01040030151015

Cited by 86 publications

(12 citation statements)

References 34 publications

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“…(1) Ocular involvement in AIDS is very common and includes various clinical presentations. (2,3,4,5,6,7,8,9) The aim of this study is to study various ocular manifestations in the cases known to be infected with HIV (Human Immunodeficiency Virus). …”

supporting

confidence: 44%

Ocular Manifestation in Hiv- A Clinical Study at Tertiary Centre

Venkat¹,

Murthy²

2018

jemds

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BACKGROUNDThe human immunodeficiency virus (HIV) infection has spread worldwide with various adverse health and economic implications, particularly in the developing world. (1) Ocular involvement in AIDS is very common and includes various clinical presentations. (2,3,4,5,6,7,8,9) The aim of this study is to study various ocular manifestations in the cases known to be infected with HIV (Human Immunodeficiency Virus). MATERIALS AND METHODSProspective clinical study from October 2010 to November 2012 at Govt. Regional Eye Hospital, Visakhapatnam, in association with Antiretroviral treatment (ART) Centre, KGH, Visakhapatnam. RESULTSOut of 960 HIV positive patients examined, 201 (20.93%) patients had ocular manifestations. Of these 201 patients, adults were 192 (95.5%) and children were 9 (4.5%). Out of these 201 patients age group 0 -20 were 16 (7.96%), age group 20 -40 were 120 (59.7%), age group 40 -60 were 55 (27.36%), age group > 60 were 10 (4.97%). 126 cases (62.7%) had anterior segment manifestations and 75 (37.3%) had posterior segment manifestations. Anterior segment manifestations include dry eye (12.43%), blepharitis (7.46%), molluscum (4.97%), OSSN (0.99%), dendritic ulcer (4.47%), fungal ulcer (3.98%), iridocyclitis (7.46%), HZO (9.45%), conjunctivitis (5.47%), nerve palsy (0.99%), stye (4.47%) and chronic dacryocystitis (0.49%). Posterior segment manifestations include HIV retinopathy (15.42%), CMV retinitis (12.43%), optic atrophy (1.49%), choroiditis (4.47%), PORN (1.49%) and retinal detachment (1.99%). Out of 201, 23 (11.44%) had CD4 count < 50, 40 (19.9%) had CD4 count 50 -100, 120 (59.7%) had CD4 count 200 -500 and 18 (8.95%) had CD4 count > 500. 93 (46.3%) were on HAART and 108 (53.7%) were on pre-HAART.

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supporting

confidence: 44%

Ocular Manifestation in Hiv- A Clinical Study at Tertiary Centre

Venkat¹,

Murthy²

2018

jemds

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“…Despite this, few cases of brainstem involvement due to toxoplasmosis are reported in literature. Isolated case reports include one patient with third nerve palsy & contralateral ataxia (Claude's syndrome) [4], two with ocular motility defects [12] and 2 with an occulomotor nerve palsy & rubral tremor [15,17]. In a prospective analysis of ophthalmological manifestation of AIDS [13], toxoplasmosis was the etiolocal agent in only one out of a total of 26 patients with cranial nerve palsy.…”

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confidence: 40%

Weber's Syndrome Due to Cerebral Toxoplasmosis

Madan

Kumar

et al. 1999

Medical Journal Armed Forces India

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“…Nº pac. : Número de pacientes; HAART: Terapia anti-retroviral combinada com síndrome da imunodeficiência adquirida, em uso ou não de terapia anti-retroviral combinada (HAART) incidência de olho seco em crianças e adultos contaminados com o vírus (11)(12)(13) . Os relatos variam quanto à incidência, observando uma variação de 12 a 80,29 % de pacientes que já apresentavam algum tipo de sofrimento celular (rosa bengala) ou que tinham teste de Schirmer anormal.…”

Section: Discussionunclassified

“…Entre as doenças oculares externas, diversos estudos em pacientes com teste anti-HIV positivo, relatam uma importante prevalência de olho seco entre os pacientes com AIDS (8)(9)(10)(11)(12)(13)(14) , em período anterior ao HAART.…”

Section: Introductionunclassified