Operative Risks Associated with Contralateral Prophylactic Mastectomy: A Single Institution Experience

Abstract

CPM patients have an increased risk of complications, especially major complications requiring rehospitalization or reoperation. These complications may influence patient and physician decisions to choose CPM.

Variation in Contralateral Prophylactic Mastectomy Rates According to Racial Groups in Young Women with Breast Cancer, 1998 to 2011: A Report from the National Cancer Data Base

“…[1][2][3][4][5][6][7] Multiple studies have questioned the benefit of CPM because it does not improve survival in average-risk women [8][9][10][11][12][13] and may increase cost 14,15 and complications. 8,16,17 Numerous studies investigating the increasing use of CPM have identified significant factors related to patient, surgeon, and treatment facility. Patients undergoing CPM tend to be younger, 2-6 have a family history of breast cancer, 1,3 and carry a BRCA mutation.…”

A multidisciplinary team approach minimises prophylactic mastectomy rates

“…Breast reconstruction adds substantially to the morbidity 28 and complications commonly affect the prophylactic side in bilateral mastectomy. 31,32 Whilst in the main, patients selecting CPM are satisfied, a proportion of patients will experience regret, issues with body image, challenges forming sexual relationships and lack feelings of femininity. 46 Moreover, whilst few studies explicitly examine cost-effectiveness of CPM, limited data suggests that CPM adds to net costs.…”

Contralateral Prophylactic Mastectomy: Current Perspectives

“…Several studies have shown that the risk of operative complications is higher with CPM, and in several studies, this risk was double that of UM. [86][87][88] In one single-institution study of 600 patients, 40% of CPM patients had complications compared to 28% of UM patients. Patients who had CPM were 1.5 times more likely to have any complication than UM patients when adjusting for multiple factors and 2.7 times more likely to have a major complication.…”