Operative morbidity and mortality for colorectal cancer: 10-years’ experience

Abstract

Background: Operative outcomes for patients with colorectal cancer are heavily dependent on the quality of surgery, the quality of pre-operative staging and treatment selection. The objective of this study was to study the operative morbidity and mortality in patients with colorectal cancer.Methods: The records of patients, with histologically proven colon or rectal cancer and underwent operative procedure, have been prospectively documented. A detailed analysis was made of patients who had a hospital stay of more than 15 days and who died within 30 days of surgical procedure.Results: 311 patients of colorectal cancer were operated. 19 patients died within 30 days of operation, an overall OMR of 6.10%. 50.80% of patients had operative morbidity events. OMR and morbidity was higher in patients undergoing emergency surgical procedure, in elderly patients, in females, patients with poor pre-operative ASA grading and in patients with advanced stages tumour.Conclusions: Adoption of various modalities of have to be considered in perspective of the age of the patient, pre-operative performance status, the type, nature and urgency of operation and pathological stage of the disease which have a bearing on the operative morbidity and mortality.

L-Arginine/NO Pathway Metabolites in Colorectal Cancer: Relevance as Disease Biomarkers and Predictors of Adverse Clinical Outcomes Following Surgery

“…As operative morbidity is dependent, among others, on the patient’s age, sex, weight, and health status [ 58 , 59 , 60 ], the potential effects of age, sex, BMI, and ASA and CCI grade on metabolite dynamics in the postoperative period were examined. None were found except for arginine and the arginine-to-ADMA ratio, which decreased directly following surgery exclusively in female patients.…”