Opening of the National Biobank of Korea as the Infrastructure of Future Biomedical Science in Korea

Cho, Sang Yun; Hong, Eock Kee; Nam, Jung Min; Han, Bogkee; Chu, Chaeshin; Park, Ok

doi:10.1016/j.phrp.2012.07.004

Cited by 40 publications

(32 citation statements)

References 11 publications

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“…En la misma vía, el Visiongain, un portal líder de información de negocios, con sede en Londres, Reino Unido, predice que el mercado mundial de los biobancos en la medicina humana generará $ US 24,4 mil millones en 2017 y una fuerte expansión hasta 2023 21 . 22,23 .…”

Section: Antecedentes Históricosunclassified

Biobanco: Herramienta fundamental para la investigación biomédica actual

Díaz¹,

Páez-Leal²,

Luna-Gonzalez³

et al. 2016

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RESUMENLa investigación biomédica enfocada a la preservación de la salud y manejo de la enfermedad requiere hoy del trabajo articulado bidireccional entre básicos y clínicos, lo cual ha generado una nueva tendencia, denominada investigación traslacional. Este tipo de investigación se fundamenta en poder brindar una atención en salud oportuna, pertinente, eficaz y personalizada, para lo cual se requieren muestras biológicas e información clínica asociada, garantizando a su vez seguridad, calidad y confidencialidad para los donantes. Promover la investigación traslacional y la aplicación de los avances del conocimiento y de la tecnología derivados de la investigación y la innovación, requiere del apoyo de infraestructuras de fácil acceso que faciliten la rápida demostración experimental de una hipótesis o la comprobación de un modelo simulado previamente. Dentro de las diversas plataformas biomédicas y de salud existentes, los Biobancos, en sus diferentes modalidades, se constituyen en una de las más atractivas plataformas a la hora de contribuir a establecer puentes entre la investigación básica y clínica, con la práctica asistencial. La necesidad de contar con muestras biológicas humanas de alta calidad y, al mismo tiempo, la obligación de preservar los derechos de los donantes, ha elevado la gestión de los Biobancos a la categoría de disciplina científico-técnica, con una complejidad particular que involucra múltiples aspectos entre los cuales se incluyen aspectos científicos, técnicos, éticos, jurídicos y sociales. Esta serie de artículos, que serán publicados en los diferentes números de la revista durante el 2016, tienen como objetivo hacer una revisión crítica de los aspectos más relevantes en torno a la gestión de los Biobancos con fines de investigación y proponer una serie de guías de manejo del material biológico humano a conservar las cuales se han desarrollado en el marco del Programa Cardiecol.

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Section: Antecedentes Históricosunclassified

Biobanco: Herramienta fundamental para la investigación biomédica actual

Díaz¹,

Páez-Leal²,

Luna-Gonzalez³

et al. 2016

revsal

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“…Specimens from 300,000 people have been collected by population-based cohorts established by the government, and the remaining specimens have been collected from 200,000 people who came to the university-affiliated hospitals [7]. In April 2012, the National Biobank of Korea opened its dedicated building, which means that a better infrastructure has been established for stable storage, management, and distribution of biospecimens for related researches (Figure 3) [8]. It has enough space to store biospecimens from 1,000,000 people (i.e., approximately 30 million vials).…”

Section: Major Achievements and Limitations Of The First Phase Of Thementioning

confidence: 99%

A Strategic Plan for the Second Phase (2013–2015) of the Korea Biobank Project

Park

Cho

Shin

et al. 2013

Osong Public Health and Research Perspectives

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The Korea Biobank Project (KBP) was led by the Ministry of Health and Welfare to establish a network between the National Biobank of Korea and biobanks run by university-affiliated general hospitals (regional biobanks). The Ministry of Health and Welfare started the project to enhance medical and health technology by collecting, managing, and providing researchers with high-quality human bioresources. The National Biobank of Korea, under the leadership of the Ministry of Health and Welfare, collects specimens through various cohorts and regional biobanks within university hospitals gather specimens from patients. The project began in 2008, and the first phase ended in 2012, which meant that there needed to be a plan for the second phase that begins in 2013. Consequently, professionals from within and outside the project were gathered to develop a plan for the second phase. Under the leadership of the planning committee, six working groups were formed to formulate a practical plan. By conducting two workshops with experts in the six working groups and the planning committee and three forums in 2011 and 2012, they have developed a strategic plan for the second phase of the KBP. This document presents a brief report of the second phase of the project based on a discussion with them.During the first phase of the project (2008–2012), a network was set up between the National Biobank of Korea and 17 biobanks at university-affiliated hospitals in an effort to unify informatics and governance among the participating biobanks. The biobanks within the network manage data on their biospecimens with a unified Biobank Information Management System. Continuous efforts are being made to develop a common standard operating procedure for resource collection, management, distribution, and personal information security, and currently, management of these data is carried out in a somewhat unified manner. In addition, the KBP has trained and educated professionals to work within the biobanks, and has also carried out various publicity promotions to the public and researchers. During the first phase, biospecimens from more than 300,000 participants through various cohorts and biospecimens from more than 200,000 patients from hospitals were collected, which were distributed to approximately 600 research projects.The planning committee for the second phase evaluated that the first phase of the KBP was successful. However, the first phase of the project was meant to allow autonomy to the individual biobanks. The biobanks were able to choose the kind of specimens they were going to collect and the amount of specimen they would set as a goal, as well as being allowed to choose their own methods to manage their biobanks (autonomy). Therefore, some biobanks collected resources that were easy to collect and the resources needed by researchers were not strategically collected. In addition, there was also a low distribution rate to researchers outside of hospitals, who do not have as much access to specimens and cases as those in hospitals. The...

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“…KoGES is a project started with the aim of collecting human biospecimens (such as whole blood, serum, plasma, urine, and blood DNA) and health-associated information from over 300,000 participants aged 40–69 years to support the studies that aim at finding out the relationships between genetic background, environmental risk factors, and lifestyle and disease development in individuals and populations [6].…”

mentioning

confidence: 99%

“…In this issue, Cho et al have explained about the current status of the National Biobank of Korea, which was opened in April 30, 2012 [6], while Lee et al have described about the Korean Biobank Project, started in 2008, including the biobank’s quality assurance [7]. So far, a total of 89 papers were produced using the distributed human biospecimens, 76 of which are enlisted in SCI/SCIE journals [6].…”

mentioning

confidence: 99%